{"id":13,"date":"2025-12-22T12:44:21","date_gmt":"2025-12-22T17:44:21","guid":{"rendered":"https:\/\/web.uri.edu\/fallini-lab\/?page_id=13"},"modified":"2026-03-24T09:53:44","modified_gmt":"2026-03-24T13:53:44","slug":"publications","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/fallini-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n<p><strong><a href=\"https:\/\/www.pnas.org\/doi\/10.1073\/pnas.2406998121\">Early disruption of the CREB pathway drives dendritic morphological alterations in FTD\/ALS cortical neurons<\/a><\/strong>. Gregoire MJ, Sirtori R, Donatelli L, Potts EM, Collins A, Zamor D, Katenka N, Fallini C.&nbsp;<em>Journal of the Proceedings of the National Academy of Science<\/em>s, December 2024<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/actaneurocomms.biomedcentral.com\/articles\/10.1186\/s40478-024-01778-z\">LINC complex alterations are a key feature of sporadic and familial ALS\/FTD<\/a><\/strong>. Sirtori R<em>, Gregoire MJ<\/em>, Potts EM<em>, Collins A<\/em>, Donatelli L<em>, Fallini C<\/em>.&nbsp;<em>Acta Neuropathologica Communications<\/em>, April 2024.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35385738\/\">ALS-associated KIF5A mutations abolish autoinhibition resulting in a toxic gain of function<\/a><\/strong>. Baron DM et al (incl Fallini C.*).&nbsp;<em>Cell Reports<\/em><a href=\"https:\/\/pubmed.ncbi.nlm.nih.gov\/35385738\/\">.&nbsp;<\/a>April 2022.&nbsp;<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.sciencedirect.com\/science\/article\/pii\/S0969996120301108\">Traffic jam at the nuclear pore: All roads lead to nucleocytoplasmic transport defects in ALS\/FTD<\/a><\/strong>.&nbsp;<strong>Fallini C<\/strong>, Khalil B, Smith CL, Rossol W.&nbsp;<em>Neurobiology of Disease<\/em>, July 2020.<\/p>\n\n\n\n<p><strong><a href=\"https:\/\/www.ncbi.nlm.nih.gov\/pmc\/articles\/PMC6707192\/\">Modulation of actin polymerization affects nucleocytoplasmic transport in multiple forms of amyotrophic lateral sclerosis<\/a>.<\/strong>&nbsp;Giampetruzzi A, Danielson EW, Gumina V, Jeon M, Boopathy S, Brown RH, Ratti A, Landers JE,&nbsp;<strong>Fallini C<\/strong>. Modulation of actin polymerization affects nucleocytoplasmic transport in the multiple forms of amyotrophic lateral sclerosis.&nbsp;<em>Nature Communications<\/em>, 2019; 10:3827.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Early disruption of the CREB pathway drives dendritic morphological alterations in FTD\/ALS cortical neurons. Gregoire MJ, Sirtori R, Donatelli L, Potts EM, Collins A, Zamor D, Katenka N, Fallini C.&nbsp;Journal of the Proceedings of the National Academy of Sciences, December 2024 LINC complex alterations are a key feature of sporadic and familial ALS\/FTD. Sirtori R, [&hellip;]<\/p>\n","protected":false},"author":5285,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-13","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/pages\/13","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/users\/5285"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":5,"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":169,"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/pages\/13\/revisions\/169"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/fallini-lab\/wp-json\/wp\/v2\/media?parent=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}