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Open any microbiology textbook and see illustrations of cells and the nucleic acids, proteins, carbohydrates and lipids inside them. Advancements in research have increased our understanding of how these biomolecules are produced, stored and degraded. But what is the story behind how these processes happen inside each cell?<\/p>\n
That\u2019s why quantitative microbiologist Keisuke Inomura is asking lots of questions about numbers.<\/p>\n
\u201cDo we know how much protein exists within the cell?\u201d he asks. \u201cHow much carbohydrate? Do these quantities change depending on the conditions? If there\u2019s more nutrients, do they have more proteins or more carbohydrates?\u201d <\/p>\n
To find answers, Inomura uses computer models based on data and mathematical theories. By focusing on cell growth, he is able to predict the impact \u00admicro\u00adorganisms can have on global biogeochemistry.
\nWhile earning his doctorate in climate physics and chemistry at the Massachusetts Institute of Technology, Inomura developed a Cell Flux Model to explain how nutrients are allocated within cells. He used the model to predict the rate of nitrogen fixation in the ocean. The model relies on data, often through collaborations with other scientists or publicly available online. Inomura then creates code to extrapolate data to fill in knowledge gaps.<\/p>\n
\u201cThere is a great deal of data available in the literature, in scientific papers, but what\u2019s missing is computational modeling with mathematical theory that connects these available data,\u201d Inomura says.
\nBorn in Japan, Inomura earned his undergraduate and master\u2019s degrees in agricultural science at Kyushu University in Fukuoka. Prior to joining the faculty at the University of Rhode Island Graduate School of Oceanography, he was a research associate at the University of Washington for three years.<\/p>\n
Inomura teaches a Python programming language coding course at GSO focused on carbon cycling. His goal is to help students develop their quantitative intuition as they run their models over and over again to predict global carbon cycling and the factors that control it.<\/p>\n
\u201cIf you change something, how many other things will change?\u201d he says. \u201cYou can repeatedly run the model and get some sense of that so that\u2019s a benefit of the class.\u201d<\/p>\n","protected":false},"excerpt":{"rendered":"
Using Computational Modeling with Mathematical Theory Keisuke Inomura, Assistant Professor of Oceanography By Janine Weisman Open any microbiology textbook and see illustrations of cells and the nucleic acids, proteins, carbohydrates and lipids inside them. Advancements in research have increased our understanding of how these biomolecules are produced, stored and degraded. But what is the story […]<\/p>\n","protected":false},"author":2120,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[7,2956],"tags":[],"class_list":["post-175507","post","type-post","status-publish","format-standard","hentry","category-aboard-gso","category-fall-2021"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/posts\/175507","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/users\/2120"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/comments?post=175507"}],"version-history":[{"count":6,"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/posts\/175507\/revisions"}],"predecessor-version":[{"id":180938,"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/posts\/175507\/revisions\/180938"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/media?parent=175507"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/categories?post=175507"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.uri.edu\/gso\/wp-json\/wp\/v2\/tags?post=175507"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}