Ayi-Bonte D, Dworacek S, Madden J, Evans J, Lofgren IE, Melanson KJ, Ward-Ritacco CL, Mortreux M<\/strong>. “Estrogen Receptor Alpha (ER\u03b1) is involved in resveratrol-mediated muscle preservation during mechanical unloading in male rats”. Muscles 2026 March. DOI:10.3390\/muscles5020023<\/a><\/p>\n\n\n\n Tsuji R, Fujita R, Hayashi T, Sadaki S, Matsumoto T, Inoue Y, Murakami Y, Hamada M, Muratani M, Kobayashi H, Yumoto A, Okada M, Kamimura D, Okada R, Suzuki T, Kurosawa R, Otsuki A, Koshiba S, Hotz-Vitaterna M, Fuller CA, Mortreux M<\/strong>, Sung DM, Ciola J, Rutkove SB, Coulombe J, Kudo T, Yamamoto M, Bouxsein ML, Shiba D, Takahashi S. “0.33g mitigates muscle atrophy while 0.67g preserves muscle function and myofiber type composition in mice during spaceflight”. Science Advances 2026 March. DOI:10.1126\/sciadv.aed2258<\/a><\/p>\n\n\n\n Weissman A, Flickinger K, Wu V, DeMaio R, Jonsson A, Prescott P, Monteleone J, Kurowski E, Guyette F, Gordon B, Mortreux M<\/strong>, Melanson K, Buysse D, Empey P, Callaway C. “Quasi-torpor for long-duration space missions”. Frontiers in Space Technologies (Space Exploration) 2024 October. DOI:10.3389\/frspt.2024.1457487<\/a><\/p>\n\n\n\n Rosa-Caldwell ME, Pandeya S, Mortreux M<\/strong>, Rutkove SB. “Predicting muscle function and mass with electrical impedance myography: a study in rat analogs of micro- and partial gravity”. Acta Astronautica 2024 July. DOI:10.1016\/j.actaastro.2024.07.017<\/a><\/p>\n\n\n\n Issertine M, Rosa-Caldwell ME, Sung DM, Rutkove SB, Mortreux M. <\/strong>“Adaptation to full weight-bearing following disuse in rats: the impact of biological sex on musculoskeletal health”. Physiological Reports 2024 February. DOI:10.14814\/phy2.15938<\/a><\/p>\n\n\n\n Rosa-Caldwell ME, Mortreux M<\/strong>, Wadhwa A, Kaiser UB, Sung DM, Bouxsein ML, Rutkove SB. “Sex differences in muscle health in simulated micro- and partial-gravity environments in rats”. Sports Medicine and Health Science 2023 September. DOI:10.1016\/j.smhs.2023.09.002 <\/a><\/p>\n\n\n\n \u200bRosa-Caldwell ME, Mortreux M<\/strong>, Wadhwa A, Kaiser UB, Sung DM, Bouxsein ML, Rutkove SB. \u201cInfluence of gonadectomy on muscle health in micro and partial-gravity environments in rats\u201d Journal of Applied Physiology 2023 June 1;134(6):1438-429. \u200bDOI: 10.1152\/japplphysiol.00023.2023<\/a><\/p>\n\n\n\n Swain P, Mortreux M<\/strong>, Laws JM, Kyriacou H, De Martino E, Winnard A, Caplan N. \u201cBone deconditioning during partial weight-bearing in rodents \u2013 a systematic review and meta-analysis\u201d. Life Sciences in Space Research, https:\/\/doi.org\/10.1016\/j.lssr.2022.07.003<\/a> Mortreux M<\/strong>, Rosa-Caldwell ME, Stiehl ID, Sung DM, Thomas NT, Fry CS & Rutkove SB. \u201cHindlimb suspension in Wistar rats: sex-based differences in muscle response\u201d. Physiological Reports, 2021 Oct;9(19):e15042. doi:10.14814\/phy2.15042.<\/a><\/p>\n\n\n\n Rosa-Caldwell ME, Mortreux M<\/strong>, Sung DM, Bouxsein ML, Kaiser U, Dunlap K, Greene NP, Rutkove SB. \u201cThe estrus cycle and skeletal muscle atrophy: investigations in rodent models of muscle loss\u201d. Exp Physiol 2021 Sep 26. doi:10.1113\/EP089962.<\/a><\/p>\n\n\n\n Swain P, Mortreux M<\/strong>, Rosa-Caldwell ME, Winnard A. \u201cRodent Partial Weight-Bearing Model: Risk of Bias Checklist\u201d. Research Gate Sep 2021. doi:10.13140\/RG.2.2.32990.77126\/1.<\/p>\n\n\n\n Pandeya SR, Nagy JA, Riveros D, Semple C, Taylor RS, Mortreux M<\/strong>, Sanchez B, Kapur K, Rutkove SB. \u201cEstimating myofiber cross-sectional area and connective tissue deposition with electrical impedance myography: a study in D2-mdx mice\u201d. Muscle Nerve 2021 Jun;63(6):941-950. doi:10.1002\/mus.27240.<\/a><\/p>\n\n\n\n Willey JS, Britten RA, Blaber E, Tahimic CGT, Chancellor J, Mortreux M<\/strong>, Sanford LD, Kubik AJ, Delp MD, Mao XW. \u201cThe individual and combined effects of spaceflight radiation and microgravity on biological systems and functional outcomes\u201d. J Environ Sci Health C Toxicol Carcinog 2021;39(2):129-179. doi:10.1080\/26896583.2021.1885283.<\/a><\/p>\n\n\n\n Malkani S, Chin CR, Cekanaviciute E, Mortreux M<\/strong>, Okinula H, Tarbier N, Schreurs AAS, Shorazi-Fard Y, Tahimic CGT, Rodriguew DR, Sexton BS, Butler D, Verma A, Bezdan D, Durmaz C, MacKay M, Malnick A, Meydan C, Li S, Garrett-Bakelman F, Fromm B, Afshinnekoo E, Langhorst BW, Dimalanta ET, Cheng-Campbell M, Blaber E, Schisler JC, Venderburg C, Friedlander MR, McDonald JT, Costes SV, Rutkove S, Grabham P, Mason CR, Beheshti A. \u201cCirculating miRNA Spaceflight Signature Reveals Targets for Countermeasure Development\u201d. Cell Reports 2020 Nov 21;108448 doi:10.1016\/j.celrep.2020.108448.<\/a><\/p>\n\n\n\n Pandeya S, Nagy JA, Riveros D, Semple C, Taylor R, Mortreux M<\/strong>, Sanchez B, Kapur K, Rutkove SB. \u201cPredicting myofiber cross-sectional area and triglyceride content with electrical impedance myography: a study in db\/db mice\u201d. Muscle Nerve 2020 doi:10.1002\/mus.27095.<\/a><\/p>\n\n\n\n Mortreux M<\/strong> and Rosa-Caldwell ME. \u201cApproaching gravity as a continuum using the rat partial weight-bearing model\u201d. Life 2020 10(10), 235 https:\/\/doi.org\/10.3390\/life10100235.<\/a><\/p>\n\n\n\n Semple C, Riveros D, Sung D-S, Nagy JA, Rutkove SB, Mortreux M<\/strong>. \u201cUsing electrical impedance myography as a biomarker of muscle deconditioning in rats exposed to micro- and partial- gravity analogs\u201d. Frontiers in Physiology 2020 doi: 10.3389\/fphys.2020.557796.<\/a><\/p>\n\n\n\n McIlduff CE, Martucci MG, Shin C, Qi K, Pacheck AK, Gutierrez H, Mortreux M<\/strong>, Rutkove SB. \u201cQuantitative ultrasound of the tongue: echo intensity is a potential biomarker of bulbar dysfunction in amyotrophic lateral sclerosis\u201d Clinical Neurophysiology 2020 Jul 17;131(10):2423-2428. DOI: 10.1016\/j.clinph.2020.06.027<\/a><\/p>\n\n\n\n Ko FC, Mortreux M<\/strong>, Riveros D, Nagy JA, Rutkove SB, Bouxsein MB. \u201cDose-dependent skeletal deficits due to varied reductions in mechanical loading in rats\u201d Npj Microgravity 2020 May 18;6:15. DOI: 10.1038\/s41526-020-0105-0<\/a><\/p>\n\n\n\n \u200b\u200bSemple C, Riveros D, Nagy JA, Rutkove SB, Mortreux M<\/strong>. \u201cPartial Weight-Bearing in Female Rats: Proof of Concept in a Martian-Gravity Analog\u201d Frontiers in Physiology 2020 Apr 3;11:302. DOI: 10.3389\/fphys.2020.00302<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Riveros D, Semple C, Bouxsein ML, Rutkove SB. \u201cThe partial weight-bearing rat model using a pelvic harness does not impact stress or hindlimb blood flow\u201d Acta Astronautica 2020 (168):249-255.https:\/\/doi.org\/10.1016\/j.actaastro.2019.12.024<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Foppen E, Denis RG, Montaner M, Kassis N, Denom J, Vincent M, Fumeron F, Kujawski-Lafourcade M, Andreelli F, Balkau B, Marre M, Roussel R, Magnan C, Gurden H, Migrenne-Li S. \u201cNew roles for Prokineticin-2 in feeding behavior, insulin resistance and type 2 diabetes: studies in mice and humans\u201d Molecular Metabolism 2019 Nov (29):182-196. DOI: 10.1016\/j.molmet.2019.08.016<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Semple C, Riveros D, Nagy JA, Rutkove SB. \u201cElectrical impedance myography for the detection of muscle inflammation induced by \u03bb-carrageenan\u201d. PLoS One 2019 Oct 1;14(10):e0223265. DOI: 10.1371\/journal.pone.0223265<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Ko FC, Riveros D, Bouxsein ML, Rutkove SB. \u201cLongitudinal time course of muscle impairments during partial weight-bearing in rats\u201d Npj Microgravity 2019 Aug 22;5:20. DOI: 10.1038\/s41526-019-0080-5<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Riveros D, Bouxsein ML, Rutkove SB. \u201cA moderate daily dose of resveratrol mitigates musle deconditioning in a Martian gravity analog\u201d Frontiers in Physiology 2019 Jul 18;10:899. DOI: 10.3389\/fphys.2019.00899<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Riveros D, Bouxsein ML, Rutkove SB. \u201cMimicking a space mission to Mars using hindlimb unloading and partial weight-bearing\u201d Journal of Visualized Experiments 2019 Apr 4;(146):59327. DOI: 10.3791\/59327<\/a><\/p>\n\n\n\n Mortreux M<\/strong>, Nagy JA, Ko FC, Bouxsein ML, Rutkove SB. \u201cA novel partial gravity ground-based analog for rats via quadrupedal unloading\u201d Journal of Applied Physiology 2018 Jul 1;125(1):175-182. \u200bDOI: 10.1152\/japplphysiol.01083.2017<\/a><\/p>\n\n\n\n Renon M, Legrand B, Blanc E, Daubigney F, Bokobza C, Mortreux M<\/strong>, Paul JL, Delabar JM, Rouach H, Andreau K, Janel N. \u201cImpact of Dyrk1A level on alcohol metabolism\u201d. Biochimica Biophysica Acta 2016 Sep;1862(9):1495-503. DOI: 10.1016\/j.bbadis.2016.05.011<\/a><\/p>\n\n\n\n Abou-Khalil R, Yang F, Mortreux M<\/strong>, Lieu S, Yu YY, Wurmser M, Pereira C, Relaix F, Miclau T, Marcucio RS, Colnot C. \u201cDelayed bone regeneration is linked to chronic inflammation in murine muscular dystrophy\u201d. Journal of Bone and Mineral Research 2014 Feb;29(2):304-15. DOI: 10.1002\/jbmr.2038<\/a><\/p>\n","protected":false},"excerpt":{"rendered":" Published Papers 2026 Ayi-Bonte D, Dworacek S, Madden J, Evans J, Lofgren IE, Melanson KJ, Ward-Ritacco CL, Mortreux M. “Estrogen Receptor Alpha (ER\u03b1) is involved in resveratrol-mediated muscle preservation during mechanical unloading in male rats”. Muscles 2026 March. DOI:10.3390\/muscles5020023 Tsuji R, Fujita R, Hayashi T, Sadaki S, Matsumoto T, Inoue Y, Murakami Y, Hamada M, […]<\/p>\n","protected":false},"author":2097,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-48","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/pages\/48","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/users\/2097"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/comments?post=48"}],"version-history":[{"count":4,"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/pages\/48\/revisions"}],"predecessor-version":[{"id":162,"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/pages\/48\/revisions\/162"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/m2b-lab\/wp-json\/wp\/v2\/media?parent=48"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}202<\/strong>4<\/h3>\n\n\n\n
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\u200bSwain P, Mortreux M<\/strong>, Laws JM, Kyriacou H, De Martino E, Winnard A, Caplan N. \u201cSkeletal muscle deconditioning during partial weight-bearing in rodents \u2013 systematic review and meta-analysis\u201d. Life Sciences in Space Research, https:\/\/doi.org\/10.1016\/j.lssr.2022.06.007<\/a>
\u200bMortreux M<\/strong>, Nagy JA, Zhong H, Sung DM, Concepcion HA, Leitner M, Dalle Pazze L, Rutkove SB. \u201cPerforming in vivo and ex vivo electrical impedance myography in rodents\u201d. J Vis Exp \u2013 June 2022. doi:10.3791\/63513<\/a><\/p>\n\n\n\n2021<\/strong><\/h3>\n\n\n\n
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