{"id":25086,"date":"2016-08-15T19:42:11","date_gmt":"2016-08-15T19:42:11","guid":{"rendered":"https:\/\/web.uri.edu\/pharmacy\/?page_id=25086"},"modified":"2019-01-17T15:55:03","modified_gmt":"2019-01-17T20:55:03","slug":"model9","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/pharmacy\/research\/rosenbaum\/sims\/model9\/","title":{"rendered":"Model 9: Multiple Bolus Injections"},"content":{"rendered":"<div class=\"cl-wrapper cl-card-wrapper\"><a class=\"cl-card  \" href=\"https:\/\/exchange.iseesystems.com\/public\/sara-rosenbaum\/mulitple-bolus-injections-pharmacokinetics\/index.html#page1\" title=\"\"><div class=\"cl-card-container media\"><img decoding=\"async\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1223\/model9-300x225.jpg\" srcset=\"\" alt=\"support\"><\/div><div class=\"cl-card-container text\"><div class=\"cl-card-text\"><h2>This model shows the typical plasma concentration profile associated with the administration of several doses of a drug over time. It demonstrates the determinants of the fluctuation in the plasma concentrations, the accumulation of the drug over the course of therapy and the resting steady state plasma concentrations.<\/h2><\/div><\/div><div class=\"cl-card-container button\">View Model<\/div><\/a><\/div>\n<h4>See Chapter 12: Multiple IV Bolus Injections in the One-Compartment Model<br \/>\nTopics relevant to this model are covered in the following sections:<\/h4>\n<p>\u2013 12.8 Simulation Exercise<\/p>\n<p>&nbsp;<\/p>\n<ul class=\"display-posts-listing\"><li class=\"listing-item\"><div class=\"content\"><section class=\"cl-wrapper cl-panel-wrapper\"><div class=\"cl-panel  \"><figure><img decoding=\"async\" src=\"https:\/\/images-na.ssl-images-amazon.com\/images\/I\/51%2BFYUXkqWL._SX348_BO1,204,203,200_.jpg\" srcset=\"\" alt=\"cholab\"><\/figure><article><h1>Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations 2nd Edition<\/h1><p><b>By: Sara E. Rosenbaum, Ph.D.<\/B><br \/>\nAn Integrated Textbook with Computer Simulations, which provides a comprehensive  account of essential pharmacokinetic and pharmacodynamic concepts. The textbook also incorporates interactive pharmacokinetic and pharmacodynamic simulation models to allow students to visualize important principles and experiment with the design of drug dosing regimens.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n<p><a class=\"cl-button  \" href=\"https:\/\/www.amazon.com\/Basic-Pharmacokinetics-Pharmacodynamics-Integrated-Simulations\/dp\/1119143152?_encoding=UTF8&amp;ie=UTF8&amp;message=&amp;riskType=expiredCard&amp;successUpdatingPreference=1&amp;updatePaymentsPortalPreferenceSuccess=true\" title=\"\">Purchase from Amazon<\/a><\/p><\/article><\/div><\/section>\n<\/div><\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>&nbsp; See Chapter 12: Multiple IV Bolus Injections in the One-Compartment Model Topics relevant to this model are covered in the following sections: \u2013 12.8 Simulation Exercise &nbsp;<\/p>\n","protected":false},"author":639,"featured_media":0,"parent":25053,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-25086","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25086","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/users\/639"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/comments?post=25086"}],"version-history":[{"count":2,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25086\/revisions"}],"predecessor-version":[{"id":37403,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25086\/revisions\/37403"}],"up":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25053"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/media?parent=25086"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}