{"id":25088,"date":"2016-08-15T19:43:20","date_gmt":"2016-08-15T19:43:20","guid":{"rendered":"https:\/\/web.uri.edu\/pharmacy\/?page_id=25088"},"modified":"2019-01-17T15:57:38","modified_gmt":"2019-01-17T20:57:38","slug":"model10","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/pharmacy\/research\/rosenbaum\/sims\/model10\/","title":{"rendered":"Model 10: Multiple Intermittent Infusions"},"content":{"rendered":"<div class=\"cl-wrapper cl-card-wrapper\"><a class=\"cl-card  \" href=\"https:\/\/exchange.iseesystems.com\/public\/sara-rosenbaum\/multiple-intermittent-infusions-pharmacokinetics\/index.html#page1\" title=\"\"><div class=\"cl-card-container media\"><img decoding=\"async\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1223\/model10.jpg\" srcset=\"\" alt=\"support\"><\/div><div class=\"cl-card-container text\"><div class=\"cl-card-text\"><h2>The model shows the unique plasma concentration-time profile associated with the administration of a drug using multiple short infusions. It demonstrates the influence of the duration of the infusion and allows the user to practice the calculation of a suitable dose and dosing interval to achieve desired peak and trough plasma concentrations of a drug.<\/h2><\/div><\/div><div class=\"cl-card-container button\">View Model<\/div><\/a><\/div>\n<h4>See Chapter 13: Multiple Intermittent Infusions<br \/>\nTopics relevant to this model are covered in the following sections:<\/h4>\n<h4>\u2013 13.5 Individualization of Dosing Regimens<\/h4>\n<p>&nbsp;<\/p>\n<ul class=\"display-posts-listing\"><li class=\"listing-item\"><div class=\"content\"><section class=\"cl-wrapper cl-panel-wrapper\"><div class=\"cl-panel  \"><figure><img decoding=\"async\" src=\"https:\/\/images-na.ssl-images-amazon.com\/images\/I\/51%2BFYUXkqWL._SX348_BO1,204,203,200_.jpg\" srcset=\"\" alt=\"cholab\"><\/figure><article><h1>Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations 2nd Edition<\/h1><p><b>By: Sara E. Rosenbaum, Ph.D.<\/B><br \/>\nAn Integrated Textbook with Computer Simulations, which provides a comprehensive  account of essential pharmacokinetic and pharmacodynamic concepts. The textbook also incorporates interactive pharmacokinetic and pharmacodynamic simulation models to allow students to visualize important principles and experiment with the design of drug dosing regimens.&nbsp;&nbsp;&nbsp;&nbsp;&nbsp;<\/p>\n<p><a class=\"cl-button  \" href=\"https:\/\/www.amazon.com\/Basic-Pharmacokinetics-Pharmacodynamics-Integrated-Simulations\/dp\/1119143152?_encoding=UTF8&amp;ie=UTF8&amp;message=&amp;riskType=expiredCard&amp;successUpdatingPreference=1&amp;updatePaymentsPortalPreferenceSuccess=true\" title=\"\">Purchase from Amazon<\/a><\/p><\/article><\/div><\/section>\n<\/div><\/li><\/ul>\n","protected":false},"excerpt":{"rendered":"<p>See Chapter 13: Multiple Intermittent Infusions Topics relevant to this model are covered in the following sections: \u2013 13.5 Individualization of Dosing Regimens &nbsp;<\/p>\n","protected":false},"author":639,"featured_media":0,"parent":25053,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-25088","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25088","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/users\/639"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/comments?post=25088"}],"version-history":[{"count":3,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25088\/revisions"}],"predecessor-version":[{"id":37421,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25088\/revisions\/37421"}],"up":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25053"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/media?parent=25088"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}