{"id":25108,"date":"2016-08-15T20:08:58","date_gmt":"2016-08-15T20:08:58","guid":{"rendered":"https:\/\/web.uri.edu\/pharmacy\/?page_id=25108"},"modified":"2016-08-15T20:08:58","modified_gmt":"2016-08-15T20:08:58","slug":"model20","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/pharmacy\/research\/rosenbaum\/sims\/model20\/","title":{"rendered":"Model 20: Pharmacodynamic DDIs"},"content":{"rendered":"
Overview<\/a> Research<\/a> Publications<\/a> iMODR<\/a> SIMS<\/a> Contact<\/a><\/div>\n

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\"model20\"<\/a><\/p>\n

This is model illustrates how drugs that have low intrinsic efficacy can antagonize, and reduce the effects of strong agonists. It illustrates how naloxone is used to treat opioid toxicity.
\nLink to Model<\/a>\n<\/div>\n

See Chapter 19: Introduction to PD Models and Integrated PK-PD Models<\/strong>
\nTopics relevant to this model are covered in the following sections:<\/p>\n

– 19.5 Pharmacodynamic Drug-Drug Interactions
\n– 19.5.1 Simulation Exercise<\/p>\n

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\"Basic<\/a><\/p>\n

Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations 2nd Edition<\/strong>
\nBy: Sara E. Rosenbaum
\nPurchase from Amazon<\/a>\n<\/div>\n","protected":false},"excerpt":{"rendered":"

Overview Research Publications iMODR SIMS Contact This is model illustrates how drugs that have low intrinsic efficacy can antagonize, and reduce the effects of strong agonists. It illustrates how naloxone is used to treat opioid toxicity. Link to Model See Chapter 19: Introduction to PD Models and Integrated PK-PD Models Topics relevant to this model […]<\/p>\n","protected":false},"author":639,"featured_media":0,"parent":25053,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-twocol.php","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-25108","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25108","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/users\/639"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/comments?post=25108"}],"version-history":[{"count":0,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25108\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/25053"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/media?parent=25108"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}