{"id":52330,"date":"2023-09-27T16:12:29","date_gmt":"2023-09-27T20:12:29","guid":{"rendered":"https:\/\/web.uri.edu\/pharmacy\/?page_id=52330"},"modified":"2024-11-15T08:23:52","modified_gmt":"2024-11-15T13:23:52","slug":"chen","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/pharmacy\/research\/chen\/","title":{"rendered":"Dr. Xinyuan Chen"},"content":{"rendered":"

Vaccine & Molecular Pharmaceutics Laboratory<\/h1><\/div><\/div>
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Overview<\/h1><\/p>\n

The Chen lab focuses on developing novel vaccine adjuvants and delivery platforms to improve drug and vaccine efficacy. We emphasize on multidisciplinary approaches to address challenges in drug\/vaccine delivery and vaccine adjuvants. In particular, we are developing novel physical and chemical adjuvants to augment vaccine-induced immune responses without provoking overt inflammation and high-density flagellin-displayed virus-like particle platform with high immunogenicity, versatility, and safety to support vaccine development. Other interests include the exploration of minimally invasive techniques (e.g., laser) to facilitate sustained transdermal drug delivery and more immunogenic vaccination, the use of omics tools to study adjuvantation mechanisms, and the development of effective adjuvants to boost mRNA vaccination.<\/p>\n

\"Professor
Professor Xinyuan Chen and Ph.D. student Yiwen Zhao work in Chen\u2019s lab on a virus-like particle platform they hope will help lead to a universal flu vaccine.<\/figcaption><\/figure>\n

News<\/h2>\n

2024-2025<\/h3>\n