{"id":6631,"date":"2013-08-27T13:11:17","date_gmt":"2013-08-27T13:11:17","guid":{"rendered":"https:\/\/web.uri.edu\/pharmacy\/?page_id=6631"},"modified":"2013-08-27T13:11:17","modified_gmt":"2013-08-27T13:11:17","slug":"flash-models-videos","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/pharmacy\/research\/rosenbaum\/imodr\/flash-models-videos\/","title":{"rendered":"iMODR: Flash-Based Models and Videos"},"content":{"rendered":"

Clinical Pharmacokinetics and Pharmacodynamics<\/strong><\/a><\/h1>\n

Sara Rosenbaum, Ph.D. <\/a><\/h3>\n

Located in Lab Module 495 on Level 4 of Avedisian Hall<\/a><\/strong><\/p>\n

Overview<\/a> Research<\/a> Publications<\/a> iMODR<\/a> Contact<\/a><\/div>\n

iMODR: Flash-Based Models and Videos<\/h3>\n

Interactive videos\u00a0are useful for visualization processes in pharmacokinetics and pharmacodynamics.
\n2-Compa\"\"rtment\u00a0Model <\/a><\/strong>
\nThis video shows the relative distribution of a drug between the central and peripheral compartments from the time the dose is\u00a0 injected up to the time the dose is eliminated from the body. It also shows how the drug\u2019s volume of distribution changes over the same period.
\n 
\n 
\n 
\nHysteresis<\/strong>
\n<\/a>
\nThis video shows the time course of the plasma concentration and drug\u00a0concentration at the site of action after an oral dose. It also shows how\u00a0response is related to the plasma concentration (hysteresis curve) the\u00a0concentration at the site of action.
\nThe videos were\u00a0created with the help of R. Wang and J. Connelly
\n 
\n 
\nFlash \u00ae CS4 is a useful platform for the development of interactive pharmacokinetic and pharmacodynamic models. An interactive version of the Indirect Effect Model I- inhibition of kin, is shown below.
\nInteractive Indirect Effect Model I: Inhibition\u00a0of kin
\nThis model was created by Ruohan Wang as partial completion of her M.S. degree in\u00a0Pharmaceutical Science.<\/p>\n","protected":false},"excerpt":{"rendered":"

Clinical Pharmacokinetics and Pharmacodynamics Sara Rosenbaum, Ph.D. Located in Lab Module 495 on Level 4 of Avedisian Hall Overview Research Publications iMODR Contact iMODR: Flash-Based Models and Videos Interactive videos\u00a0are useful for visualization processes in pharmacokinetics and pharmacodynamics. 2-Compartment\u00a0Model This video shows the relative distribution of a drug between the central and peripheral compartments from […]<\/p>\n","protected":false},"author":639,"featured_media":0,"parent":6494,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"page-twocol.php","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-6631","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/6631","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/users\/639"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/comments?post=6631"}],"version-history":[{"count":0,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/6631\/revisions"}],"up":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/pages\/6494"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/media?parent=6631"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}