{"id":3996,"date":"2013-08-16T17:04:13","date_gmt":"2013-08-16T17:04:13","guid":{"rendered":"https:\/\/web.uri.edu\/pharmacy\/?p=3996"},"modified":"2013-08-16T17:04:13","modified_gmt":"2013-08-16T17:04:13","slug":"php542-evaluation-of-controversies-in-drug-literature","status":"publish","type":"post","link":"https:\/\/web.uri.edu\/pharmacy\/2013\/08\/16\/php542-evaluation-of-controversies-in-drug-literature\/","title":{"rendered":"PHP542 Evaluation of Controversies in Drug Literature"},"content":{"rendered":"\n\n\n\n\n\n\n
Credits<\/strong><\/td>\n<\/td>\n3 credits<\/td>\n<\/tr>\n
Coordinator\/Primary Instructor<\/strong><\/td>\n<\/td>\n<\/td>\n<\/tr>\n
<\/td>\n<\/td>\n<\/td>\n<\/tr>\n
Catalog Description<\/strong><\/td>\n<\/td>\nThrough critical review of literature, controversies in drug therapy and drug-associated illness will be evaluated to improve students\u2019 knowledge and analytical skills.<\/td>\n<\/tr>\n
Estimated Enrollment<\/strong><\/td>\n<\/td>\n30 (Preference will be given to P3 students.)<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Detailed Course Description<\/h3>\n

Drug-induced diseases (or adverse drug reactions – ADRs) is one of the leading causes of morbidity\/mortality in health care. \u00a0The use of increased number of drugs, as well as drug combinations, leads to more opportunity for ADRs to occur, as a result of additive effects of or drug interactions between concomitant medications.\u00a0 Pharmacists need a solid understanding of the frequency & mechanisms by which drug-induced disease occurs to minimize\/prevent ADRs as they pertain to commonly used and\/or high risk medications.\u00a0 The recognition of rare & unexpected ADRs is also important.
\nThe first portion of this course is designed to teach students with how to identify, scrutinize, and utilize the information from the medical literature.\u00a0 Development of these skills will provide students with the ability to evaluate validity of existing literature in the area of drug-induced disease.\u00a0 It will also allow the successful student to stay abreast of therapeutic advances not found in textbooks.
\nThe second portion of this course focuses on special topics in drug-induced disease.
\nEmphasis is placed on the mechanisms by which drugs cause disease (e.g., pharmacologic, allergic, idiosyncratic and toxicologic), risk factors, the clinical markers and signs and symptoms of these conditions, and recommendations regarding preventative strategies and treatment.\u00a0 The medical literature is used to augment the lectures and to facilitate discussions.
\nActivities\/Class format
\n<\/strong>Didactic lectures:<\/em> Several lectures will be provided throughout the semester covering drug-induced disease topics beyond that of required courses.\u00a0 Topics that have been discussed in past curriculum include NSAID-induced peptic ulcer disease, nephrotoxicity related to aminoglycoside use, drug allergies\/cross-sensitivities, antibiotic-induced C. difficile<\/em>, pregnancy categorization of drugs for teratogenic potential, and antipsychotic-related hyperglycemia.
\nClass activities:\u00a0<\/em> There are several assignments and\/or in-class activities in which you will be required to participate.\u00a0 If you are not present, you cannot receive credit.\u00a0 Past examples include:\u00a0 MedWatch<\/em> reporting, clinical drug consult, journal article presentations.
\nExaminations:\u00a0<\/em> Two exams will be given during the semester.\u00a0 Exams are not cumulative and will cover lecture material noted in the syllabus.\u00a0 Exam questions will be taken from the material covered in didactic lectures, assigned readings & journal club articles.\u00a0 Students are responsible for attending each examination.
\nGrading format<\/em> (subject to change):
\nAttendance and participation – 10%
\nAssignments – 30%
\nJournal Club Presentation – 20%
\nMidterm exam \u2013 20%
\nFinal exam \u2013 20%
\nLearning Objectives:<\/strong><\/p>\n

    \n
  1. Distinguish between different research study designs & their inherent strengths & weaknesses.<\/li>\n
  2. Evaluate primary literature for the validity of research design, results & make conclusions about the clinical significance of drug-induced disease in question.<\/li>\n
  3. Be able to select the appropriate resource(s) \u2013 textbook, drug database, primary literature, etc \u2013 to answer a specific drug-induced disease question.<\/li>\n
  4. Learn how to participate in the drug therapy decision-making process as it pertains to drug-induced disease:<\/li>\n<\/ol>\n
      \n
        \n
      1. Obtain & evaluate relevant patient information (eg. thorough medication history)<\/li>\n
      2. Discuss the mechanisms by which drugs cause disease.<\/li>\n
      3. Describe the signs\/symptoms associated with specific drug-associated illnesses & the typical timeframe of onset.<\/li>\n
      4. Identify the factors that increase risk of drug-induced disease.<\/li>\n
      5. Evaluate case studies & published adverse drug reaction literature<\/li>\n
      6. Recommend a treatment plan for management of the drug-induced disease & outline strategies for prevention in the future, based on evaluation of published literature on ADRs.<\/li>\n<\/ol>\n<\/ol>\n

        Provide recommendations in drug consult format.<\/p>\n","protected":false},"excerpt":{"rendered":"

        Credits 3 credits Coordinator\/Primary Instructor Catalog Description Through critical review of literature, controversies in drug therapy and drug-associated illness will be evaluated to improve students\u2019 knowledge and analytical skills. Estimated Enrollment 30 (Preference will be given to P3 students.) Detailed Course Description Drug-induced diseases (or adverse drug reactions – ADRs) is one of the leading […]<\/p>\n","protected":false},"author":639,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[62,68],"tags":[],"class_list":["post-3996","post","type-post","status-publish","format-standard","hentry","category-prof-electives","category-prof-electives-notoffer"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/posts\/3996","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/users\/639"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/comments?post=3996"}],"version-history":[{"count":0,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/posts\/3996\/revisions"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/media?parent=3996"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/categories?post=3996"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.uri.edu\/pharmacy\/wp-json\/wp\/v2\/tags?post=3996"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}