{"id":13,"date":"2025-12-22T12:44:21","date_gmt":"2025-12-22T17:44:21","guid":{"rendered":"https:\/\/web.uri.edu\/quinlan-lab\/?page_id=13"},"modified":"2026-05-20T11:17:10","modified_gmt":"2026-05-20T15:17:10","slug":"publications","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/quinlan-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n

Selected Publications<\/em><\/p>\n\n\n\n

Modeling cerebral palsy in animals.<\/strong><\/a> Quinlan KA*, Reedich EJ*, Mena Avila E*, Moline BC*, Genry LT*, Detloff MR, Katholi BR, Gaebler-Spira D, Aravamuthan BR. Developmental Medicine & Child Neurology, <\/em>January 2026<\/p>\n\n\n\n

A low-cost, open-source device to evaluate limb stiffness in a rabbit model of cerebral palsy.<\/a> <\/strong>Steele PR*, Feldmann J*, Quinlan KA*, Manuel M* Frontiers in Bioengineering and Biotechnology<\/em> June 2025.<\/p>\n\n\n\n

Sex-related differences in motoneuron firing behavior during typical development.<\/strong><\/a> Yacyshyn AF, Mohammadalinejad G, Afsharipour B, Duchcherer J, Bashuk J, Bennett DJ, Negro F, Quinlan KA*, Gorassini MA. Journal of Neurophysiology<\/em> March 2025<\/p>\n\n\n\n

Gain-of-function mutations of TRPV4 acting in endothelial cells drive blood-CNS barrier breakdown and motor neuron degeneration in mice<\/a><\/strong>. Sullivan JM et al (incl. Quinlan KA*). Science Translational Medicine<\/em>, May 2024.<\/p>\n\n\n\n

Intrinsic motoneuron properties in typical human development<\/a><\/strong>. Mohammadalinejad G et al (incl. Quinlan KA*). Journal of Physiology<\/em>, March 2024.<\/p>\n\n\n\n

Mitigating aberrant Cdk5 activation alleviates mitochondrial defects and motor neuron disease symptoms in spinal muscular atrophy. <\/a><\/strong>Miller N et al (incl. Quinlan KA*). PNAS<\/em>. July 2023.<\/p>\n\n\n\n

Facilitation of sensory transmission to motoneurons during cortical or sensory evoked primary afferent depolarization (PAD) in humans<\/a>. <\/strong>Metz K et al (incl. Quinlan KA*). Journal of Physiology<\/em>. March 2023.<\/p>\n\n\n\n

Inhibitory interneurons show early dysfunction in a SOD1 mouse model of amyotrophic lateral sclerosis<\/a>.<\/a><\/strong> Cavarsan CF*, Steele PR*, Genry LT*, Reedich EJ*, McCane LM, LaPre KJ*, Puritz AC, Manuel M*, Katenka N, Quinlan KA*. Journal of Physiology<\/em>. February 2023. (Editor\u2019s Pick)<\/p>\n\n\n\n

Artificial extracellular matrix scaffolds of mobile molecules enhance maturation of human stem cell-derived neurons<\/strong><\/a>. Alvarez Z et al (including Quinlan KA*). Cell Stem Cell<\/em>. January 2023.<\/p>\n\n\n\n

Spinal motoneurons respond aberrantly to serotonin in a rabbit model of cerebral palsy<\/strong><\/a>. Reedich EJ*, Genry LT*, Steele PR*, Mena Avila E*, Dowaliby L*, Drobyshevsky A*, Manuel M*, and Quinlan KA*. Journal of Physiology<\/em>, 2023.<\/p>\n\n\n\n

Enhanced nociceptive behavior and expansion of associated primary afferents in a rabbit model of cerebral palsy<\/a>. <\/strong>Reedich EJ*, Genry LT*, Singer MA, Cavarsan CF*, Avila EM*, Boudreau DM*, Brennan MC, Garrett AM, Dowaliby L*, Detloff MR, Quinlan KA*. Journal of Neuroscience Research<\/em>, July 2022.<\/p>\n\n\n\n

Estimation of self-sustained activity from persistent inward currents using firing rate profiles of multiple motor units in humans<\/a>. <\/strong>Afsharipour B, Manzur N, Duchcherer J, Fenrich KF, Thompson CK, Negro F, Quinlan KA*, Bennett DJ, and Gorassini MA. Journal of Neurophysiology<\/em>, May 2020.<\/p>\n\n\n\n

Altered Motoneuron Properties Contribute to Motor Deficits in a Rabbit Hypoxia-Ischemia Model of Cerebral Palsy<\/a>.<\/strong> Steele PR*, Cavarsan CF*, Dowaliby L*, Westefeld M*, Katenka N, Drobyshevsky A, Gorassini M, Quinlan KA*. Frontiers in Cellular Neuroscience, March 2020. <\/p>\n\n\n\n

Hyperexcitability precedes motoneuron loss in the Smn2B\/-mouse model of spinal muscular atrophy<\/strong><\/a>. Quinlan KA*, Reedich E, Arnold WD, Puritz A, Cavarsan CF*, Heckman CJ, DiDonato CJ. Journal of Neurophysiology, July 2019.  <\/p>\n\n\n\n

Animal models of developmental motor disorders: parallels to human motor dysfunction in cerebral palsy<\/strong><\/a>. Cavarsan CF*, Gorassini MA, Quinlan KA*. Journal of Neurophysiology, September 2019.  <\/p>\n\n\n\n

Dissecting the functional consequences of de novo DNA methylation dynamics in human motor neuron differentiation and physiology.<\/strong> Ziller, M.J. et al. Cell Stem Cell 22, 1\u201316 (2018).<\/p>\n\n\n\n

Chronic EMGs in treadmill running SOD1 mice reveal early changes in muscle activation.<\/strong> Quinlan, KA* et al. J Physiol 595, 5387\u20135400 (2017).<\/p>\n\n\n\n

Spinal cord injury in hypertonic newborns after antenatal hypoxia-ischemia in rabbit cerebral palsy model<\/strong>. Drobyshevsky, A. and Quinlan, KA*.  Exp Neurol 293, 13\u201326 (2017).<\/p>\n\n\n\n

Comparison of dendritic calcium transients in juvenile wild type and SOD1G93A mouse lumbar motoneurons.<\/strong> Quinlan, KA* et al. Front Cell Neurosci 9, 139 (2015).<\/p>\n\n\n\n

Motor neuron rescue in spinal muscular atrophy mice demonstrates that sensory-motor defects are a consequence, not a cause, of motor neuron dysfunction.<\/strong> Gogliotti, R et al. J Neurosci 32, 3818\u20133829 (2012).<\/p>\n\n\n\n

Electrophysiological and molecular contributions to ALS pathology.<\/strong> Quinlan, KA* Integr Comp Biol 51, 913\u201325 (2011).<\/p>\n\n\n\n

Altered postnatal maturation of electrical properties in spinal motoneurons in an ALS mouse model.<\/strong> Quinlan, KA* et al. J Physiol 589, 2245\u201360 (2011).<\/p>\n\n\n\n

Genetic Ablation of V2a Ipsilateral Interneurons Disrupts Left-Right Locomotor Coordination in Mammalian Spinal Cord.<\/strong> Crone, SA, Quinlan, KA*. (equal authorship) et al. Neuron 60, 70\u201383, (2008).<\/p>\n\n\n\n

Cellular and synaptic actions of acetylcholine in the lamprey spinal cord.<\/strong> Quinlan, KA* (corresponding author) and Buchanan, J.T. J Neurophysiol 100, 1020\u20131031 (2008).<\/p>\n","protected":false},"excerpt":{"rendered":"

Selected Publications Modeling cerebral palsy in animals. Quinlan KA*, Reedich EJ*, Mena Avila E*, Moline BC*, Genry LT*, Detloff MR, Katholi BR, Gaebler-Spira D, Aravamuthan BR. Developmental Medicine & Child Neurology, January 2026 A low-cost, open-source device to evaluate limb stiffness in a rabbit model of cerebral palsy. Steele PR*, Feldmann J*, Quinlan KA*, Manuel M* Frontiers in Bioengineering and Biotechnology June 2025. […]<\/p>\n","protected":false},"author":5285,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-13","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/pages\/13","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/users\/5285"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/comments?post=13"}],"version-history":[{"count":5,"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/pages\/13\/revisions"}],"predecessor-version":[{"id":131,"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/pages\/13\/revisions\/131"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/quinlan-lab\/wp-json\/wp\/v2\/media?parent=13"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}