{"id":44,"date":"2013-12-09T13:18:48","date_gmt":"2013-12-09T18:18:48","guid":{"rendered":"https:\/\/web.uri.edu\/inbre-core-facility\/?page_id=44"},"modified":"2023-12-15T16:44:31","modified_gmt":"2023-12-15T21:44:31","slug":"general-analytical-equipment","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/general-analytical-equipment\/","title":{"rendered":"General Instruments"},"content":{"rendered":"<div class=\"fullwidth\">\n<section class=\"cl-wrapper cl-menu-wrapper\"><nav id=\"\" class=\"cl-menu  \" data-name=\"Core-Facility-Instruments\" data-show-title=\"0\"><ul id=\"menu-core-facility-instruments\" class=\"cl-menu-list cl-menu-list-no-js\"><li id=\"menu-item-11111\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-11111\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/\">Core Facility<\/a><\/li>\n<li id=\"menu-item-13165\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13165\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/contact\/\">Contact<\/a><\/li>\n<li id=\"menu-item-35361\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35361\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core_facility_instruments\/\">Instruments<\/a><\/li>\n<li id=\"menu-item-13387\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13387\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-fees\/\">Reservation and Fees<\/a><\/li>\n<\/ul><\/nav><\/section>\n<div class=\"title\"><span style=\"font-family: Charter, Georgia, serif;font-size: 20px\"><section class=\"cl-wrapper cl-menu-wrapper\"><nav id=\"\" class=\"cl-menu  \" data-name=\"CORE_Instruments\" data-show-title=\"0\"><ul id=\"menu-core_instruments\" class=\"cl-menu-list cl-menu-list-no-js\"><li id=\"menu-item-35340\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35340\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/cell-culture\/\">Cell Culture<\/a><\/li>\n<li id=\"menu-item-35334\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35334\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/chromtotography\/\">Chromatography<\/a><\/li>\n<li id=\"menu-item-35335\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35335\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/mass-spectrometry\/\">Mass Spectrometry<\/a><\/li>\n<li id=\"menu-item-35342\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35342\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/spectrometry\/\">Spectrometry<\/a><\/li>\n<li id=\"menu-item-35336\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35336\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/microscopy-imaging\/\">Microscopy &amp; Imaging<\/a><\/li>\n<li id=\"menu-item-36773\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-36773\"><a href=\"https:\/\/web.uri.edu\/riinbre\/single-cell-and-spatial-omics-instruments\/\">Single Cell and Spatial Omics<\/a><\/li>\n<li id=\"menu-item-35341\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35341\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/general-analytical-equipment\/\">General Instruments<\/a><\/li>\n<li id=\"menu-item-35362\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35362\"><a href=\"https:\/\/web.uri.edu\/riinbre\/core-facility\/instrument-recommendations\/\">Instrument Recommendations<\/a><\/li>\n<\/ul><\/nav><\/section><\/span><\/div>\n<\/div>\n<div class=\"fullwidth\">\n<div class=\"title\">\n<h3>Ultra Centrifuge <img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-31648 size-full\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Ultra-Centrifuge.jpg\" alt=\"Beckman Optima\u2122 L-100 XP\" width=\"150\" height=\"150\"><\/h3>\n<p>The Beckman Optima\u2122 L-100 XP ultracentrifuge provides an on-board computer, Optima eXPert software and a touch screen.&nbsp; It delivers functionality, optimized user efficiencies, and fast turnarounds.<\/p>\n<p>&nbsp;<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"title\">\n<h3>High Speed Centrifuge <img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-31650 size-thumbnail\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/High-Speed-Centrifuge-150x150.jpg\" alt=\"Beckman Coulter Avanti-J-E high-speed centrifuge\" width=\"150\" height=\"150\"><\/h3>\n<\/div>\n<div id=\"post-825\" class=\"post-825 post type-post status-publish format-standard has-post-thumbnail hentry category-general-analytical-equipment\">\n<div class=\"entry\">\n<p>The Beckman Coulter Avanti-J-E high-speed centrifuge comes with three fixed angle rotors:&nbsp;<br \/>\n<strong>JA-10,<\/strong> 6 x 500 and 250ml adapters,10,000rpm,<br \/>\n<strong>JA-20.1,<\/strong> 32 x 15ml, 20000rpm&nbsp;<br \/>\n<strong>JA-20, <\/strong>8 x 50ml, 20,000 rpm<\/p>\n<\/div>\n<\/div>\n<div class=\"title\">\n<h3>&nbsp;<\/h3>\n<h3>Benchtop Centrifuge<\/h3>\n<\/div>\n<\/div>\n<div id=\"post-823\" class=\"post-823 post type-post status-publish format-standard has-post-thumbnail hentry category-general-analytical-equipment\">\n<div class=\"entry\">\n<div class=\"fullwidth\">\n<p>The Heraeus Multifuge X3R is a compact benchtop centrifuge.&nbsp; <img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-31651 size-medium\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Benchtop-Centrifuge-300x144.png\" alt=\"Heraeus Multifuge X3R\" width=\"300\" height=\"144\" srcset=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Benchtop-Centrifuge-300x144.png 300w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Benchtop-Centrifuge.png 324w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><br \/>\nThe user-friendly control panel makes it easy to pre-set the speed, RCF value, running time, temperature, and running profile (acceleration and braking curves). You can choose between the display of speed and RCF or the entry mode.&nbsp; With the help of the PULSE key, you can also centrifuge a sample for just a few seconds.<\/p>\n<p>&nbsp;<\/p>\n<div class=\"title\">\n<h3>&nbsp;<\/h3>\n<h3>Beckman Optima MAX-TL Ultracentrifuge<img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-35443 alignright\" src=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Lonza.jpeg\" alt=\"\" width=\"261\" height=\"193\"><\/h3>\n<\/div>\n<p>The Optima MAX-TL tabletop ultracentrifuge can run up to 120,000 RPM in 1000-RPM increments for a variety of application. It holds micro tubes (from 0.25ml up to 13.5 ml).<\/p>\n<div class=\"title\">\n<h3>&nbsp;<\/h3>\n<h3>&nbsp;<\/h3>\n<h3>Microcentrifuge <img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-31652 size-thumbnail@2x\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Microcentrifuge-300x300.jpg\" alt=\"Eppendorf Centrifuge 5417 R\" width=\"300\" height=\"300\" srcset=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Microcentrifuge-300x300.jpg 300w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Microcentrifuge-150x150.jpg 150w\" sizes=\"auto, (max-width: 300px) 100vw, 300px\" \/><\/h3>\n<\/div>\n<\/div>\n<div id=\"post-1060\" class=\"post-1060 post type-post status-publish format-standard has-post-thumbnail hentry category-general-analytical-equipment\">\n<div class=\"entry\">\n<div class=\"fullwidth\">\n<p>The Eppendorf Centrifuge 5417 R is a refrigerated bench-top centrifuge. Eppendorf Micro Test Tubes can be centrifuged at 20800 rcf (14000 rpm). It is possible to attain an rcf of up to 25000 using a special 24-position rotor. For special applications a swing-bucket rotor is available with 8 positions for centrifuging Eppendorf Micro Test Tubes at a maximum rotational speed of 10500 rpm (11700 rcf). PCR tubes can be centrifuged in a rotor which can accommodate six 8-tube strips.<\/p>\n<h3>&nbsp;<\/h3>\n<h3>Tycho NT.6<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-15124 size-full\" style=\"font-style: normal;font-weight: 400;font-family: Hind, Arial, sans-serif;font-size: 20px\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/TychoNT.6_LeftWholder2-e1515281867866.png\" alt=\"\" width=\"250\" height=\"260\">The Tycho NT.6 verifies protein quality by looking at the structural integrity (or foldedness) of a protein. Changes in the intrinsic fluorescence of the sample are measured as a thermal ramp is applied. Changes in the fluorescence signal indicate transitions in the folding state of the protein. The Tycho can be used to study the stability of protein samples in different buffers or at different pH values. The measurement is completed in three minutes and uses a capillary tube to hold the sample.<\/p>\n<p>&nbsp;<\/p>\n<h3>Biacore T200 SPR<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"wp-image-15175 size-medium alignright\" style=\"font-style: normal;font-weight: 400;font-family: Hind, Arial, sans-serif;font-size: 20px\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/9838_50054-284x300.jpg\" alt=\"\" width=\"284\" height=\"300\" srcset=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/9838_50054-284x300.jpg 284w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/9838_50054-364x384.jpg 364w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/9838_50054-500x528.jpg 500w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/9838_50054.jpg 520w\" sizes=\"auto, (max-width: 284px) 100vw, 284px\" \/>The Biacore T200 is a surface plasmon resonance instrument which can be used to characterize molecular interactions between biomolecules ranging in size from ions to viruses. The Biacore software provides a range of tools for kinetic analyses. These analyses can be performed using a multicycle approach (many samples against one ligand or when different ligands are immobilized), or alternatively, using fast, single cycle kinetics.<\/p>\n<\/div>\n<\/div>\n<p style=\"text-align: left\">&nbsp;<\/p>\n<div class=\"entry\">\n<div class=\"fullwidth\">\n<h3>&nbsp;<\/h3>\n<h3>Leica CryoStat CM3050 S<\/h3>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-15175 \" style=\"font-style: normal;font-weight: 400;font-family: Hind, Arial, sans-serif;font-size: 20px\" src=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Leica_CM3050S_Precision_Cooling-300x220.jpg\" alt=\"\" width=\"286\" height=\"233\">Processing multiple specimen and performing serial cuts can result in high section numbers. Nevertheless, reproducibility can&#8217;t be compromised. Permanent attention to detail and many hours in front of the cryostat can be exhausting for the user. The Leica CM3050 S cryostat is designed to help with exactly these time-consuming jobs.<\/p>\n<\/div>\n<\/div>\n<p>&nbsp;<\/p>\n<h3>Nanotemper Microscale Monolith X <img loading=\"lazy\" decoding=\"async\" class=\" wp-image-35416 alignright\" src=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Monolith.jpg\" alt=\"\" width=\"324\" height=\"275\"><\/h3>\n<p>The Monolith system&#8217;s fluorescence-based detection accurately assesses biomolecular interactions, employing MicroScale Thermophoresis (MST) to measure binding affinities, kinetics, and thermodynamics.<\/p>\n<\/div>\n<p>&nbsp;<\/p>\n<\/div>\n<\/div>\n<h3>&nbsp;<\/h3>\n<h3>Lonza 4D Nucleofector<img loading=\"lazy\" decoding=\"async\" class=\" wp-image-35438 alignright\" src=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Lonza.jpg\" alt=\"\" width=\"305\" height=\"261\"><\/h3>\n<p>The Lonza 4D Nucleofector is a system designed for efficient transfection of various cell types. It comprises the 4D-Nucleofector X Unit, facilitating transfection of diverse cell numbers. The Core Unit controls the system for transfecting cell lines and primary cells.<\/p>\n<p>&nbsp;<\/p>\n<p>&nbsp;<\/p>\n<h3>MerMade 4 Oligonucleotide synthesizer<img loading=\"lazy\" decoding=\"async\" class=\"size-full wp-image-35456 alignright\" src=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Mermade-DNA-synthesizer.jpg\" alt=\"\" width=\"188\" height=\"145\"><\/h3>\n<p>The MerMade oligonucleotide synthesizer is<br \/>\ndesigned to synthesize DNA, RNA and LNA oligonucleotides<br \/>\nin column format using standard or<br \/>\nmodified chemistries.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Ultra Centrifuge The Beckman Optima\u2122 L-100 XP ultracentrifuge provides an on-board computer, Optima eXPert software and a touch screen.&nbsp; It delivers functionality, optimized user efficiencies, and fast turnarounds. &nbsp; &nbsp; High Speed Centrifuge The Beckman Coulter Avanti-J-E high-speed centrifuge comes with three fixed angle rotors:&nbsp; JA-10, 6 x 500 and 250ml adapters,10,000rpm, JA-20.1, 32 x [&hellip;]<\/p>\n","protected":false},"author":1036,"featured_media":0,"parent":1598,"menu_order":10,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"class_list":["post-44","page","type-page","status-publish","hentry"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/pages\/44","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/users\/1036"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/comments?post=44"}],"version-history":[{"count":9,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/pages\/44\/revisions"}],"predecessor-version":[{"id":35457,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/pages\/44\/revisions\/35457"}],"up":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/pages\/1598"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/media?parent=44"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}