{"id":27584,"date":"2021-07-16T15:58:33","date_gmt":"2021-07-16T19:58:33","guid":{"rendered":"https:\/\/web.uri.edu\/riinbre\/?p=27584"},"modified":"2021-12-14T16:38:45","modified_gmt":"2021-12-14T21:38:45","slug":"ecd-awardees","status":"publish","type":"post","link":"https:\/\/web.uri.edu\/riinbre\/ecd-awardees\/","title":{"rendered":"ECD Awardees"},"content":{"rendered":"<div class=\"fullwidth\">\n<p><section class=\"cl-wrapper cl-menu-wrapper\"><nav id=\"\" class=\"cl-menu  \" data-name=\"Developmental-Research-Project-Program\" data-show-title=\"0\"><ul id=\"menu-developmental-research-project-program\" class=\"cl-menu-list cl-menu-list-no-js\"><li id=\"menu-item-13063\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13063\"><a href=\"https:\/\/web.uri.edu\/riinbre\/research\/ecd\/\">Early Career Development<\/a><\/li>\n<li id=\"menu-item-13072\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13072\"><a href=\"https:\/\/web.uri.edu\/riinbre\/research\/surf-training-award\/\">Summer Training and Research (STAR)<\/a><\/li>\n<li id=\"menu-item-13075\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13075\"><a href=\"https:\/\/web.uri.edu\/riinbre\/mentoring\/\">Mentoring<\/a><\/li>\n<li id=\"menu-item-23477\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-23477\"><a href=\"https:\/\/web.uri.edu\/riinbre\/research\/administrative-supplemental-awards\/\">Administrative Supplemental Awards<\/a><\/li>\n<li id=\"menu-item-15439\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-15439\"><a href=\"https:\/\/web.uri.edu\/riinbre\/teaching-postdoc-fellowships\/\">Teaching Postdoc Fellowships<\/a><\/li>\n<li id=\"menu-item-35586\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-35586\"><a href=\"https:\/\/web.uri.edu\/riinbre\/ccri-faculty-fellowship-program\/\">CCRI Faculty Fellowship Program<\/a><\/li>\n<li id=\"menu-item-15680\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-15680\"><a href=\"https:\/\/web.uri.edu\/riinbre\/research\/grant-research-service\/\">Grant Research Service<\/a><\/li>\n<li id=\"menu-item-13906\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13906\"><a href=\"https:\/\/web.uri.edu\/riinbre\/research\/publications\/\">Publications<\/a><\/li>\n<li id=\"menu-item-13939\" class=\"menu-item menu-item-type-post_type menu-item-object-page menu-item-13939\"><a href=\"https:\/\/web.uri.edu\/riinbre\/research\/research-presentations\/\">Presentations<\/a><\/li>\n<\/ul><\/nav><\/section><strong><img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-30275 size-third_column\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis_Scaplen_Stack-364x171.jpg\" alt=\"\" width=\"364\" height=\"171\" srcset=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis_Scaplen_Stack-364x171.jpg 364w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis_Scaplen_Stack-300x141.jpg 300w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis_Scaplen_Stack-768x360.jpg 768w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis_Scaplen_Stack-500x234.jpg 500w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis_Scaplen_Stack.jpg 862w\" sizes=\"auto, (max-width: 364px) 100vw, 364px\" \/><br \/>\n<\/strong><strong>A Warm Welcome to&nbsp;<br \/>\n<\/strong>Dr. Lindsay Green-Gavrielidis, Salve Regina University<br \/>\nDr. Kristin Scaplen, Bryant University<br \/>\nDr. Tyler Stack, Providence College<\/p>\n<\/div>\n<div class=\"fullwidth\">\n<hr>\n<p><strong>\u201cAssessing the impact of harmful macroalgal blooms on costal environmental health.\u201d Dr. Lindsay Green-Gavrielidis, <\/strong><strong>Assistant Professor, Salve Regina University<br \/>\n<\/strong>The goal of Dr. Green-Gavrielidis\u2019 ECD project is assessing the impacts of harmful macroalgal blooms on higher trophic levels and coastal environmental health. Her research focuses on the understudied impact of green macroalgal toxins to develop an easy screening protocol. Specific objectives are to assess the sublethal and lethal impacts of green tide toxins on higher trophic levels and develop screening protocols to assess green tide impacts in real time. Seaweeds, a vital component of nearshore marine ecosystems, form the base of marine food webs and can serve as habitat for invertebrates and small fish. Harmful macroalgal blooms, large heaps of drifting macroalgae accumulating in shallow low wave energy environments, are usually driven by excess nutrients and reduced herbivory.<img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-29697 alignleft\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis-green-tide-300x174.jpg\" alt=\"\" width=\"300\" height=\"174\"><\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-27625 alignright\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis-Seaweed-LONG-225x300.jpg\" alt=\"\" width=\"225\" height=\"300\" srcset=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis-Seaweed-LONG-225x300.jpg 225w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/Green-Gavrielidis-Seaweed-LONG.jpg 359w\" sizes=\"auto, (max-width: 225px) 100vw, 225px\" \/><span style=\"font-family: Charter, Georgia, serif;font-size: 20px\">Green tides are prevalent harmful macroalgal blooms that are widespread globally and domestically. \u201cGreen tides have extensive ecological and economic impacts that can disrupt food webs and human food supply and can interfere with recreation and tourism and produce harmful toxins (e.g. dopamine) that negatively impact organisms or release noxious odors that are respiratory irritants.\u201d<br \/>\n<\/span>Dr. Green-Gavrielidis is passionate about teaching in the classroom, lab, and field and hopes to continue to inspire people to appreciate, study, and conserve the natural world. Her ultimate goal is \u201cfor people to gain an appreciation for the role of seaweeds and other overlooked organisms that serve vital roles in maintaining the health of our coastal ecosystems.\u201d She enjoys introducing people to edible seaweeds and hopes that eating seaweed alongside oysters, lobsters, and fish will become a standard societal practice.&nbsp;<br \/>\nDr. Lindsay Green-Gavrielidis received her B.S. (biology) and M.Sc. (marine biology) degrees from Northeastern University, completed her doctorate (plant biology) at the University of New Hampshire (studying seaweed physiology and aquaculture), and her postdoctoral training at the University of Rhode Island (ecology and physiology of harmful macroalgal blooms in Narragansett Bay). She joined the Biology and Biomedical Sciences Department at Salve Regina University (SRU) in 2019 and is an Assistant Professor.<\/p>\n<hr>\n<\/div>\n<p>&nbsp;<\/p>\n<div class=\"fullwidth\">\n<p><strong>\u201cNeural mechanisms underlying maladaptive reward memories in Drosophila.\u201d <img loading=\"lazy\" decoding=\"async\" class=\"alignright wp-image-30286 size-medium\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Scaplen_Neuron-Postsynaptic-MAX_006350_2932-18C_F-17do_MB083C_R1_sGIN_TGEA_GFP-Ck-488_TomDsRed-Rb-568_Brp-SNAP_40x0.5-Tile_C0006-C6_180217-300x300.jpg\" alt=\"\" width=\"300\" height=\"300\"><\/strong><strong>Dr. Kristin Scaplen, <\/strong><strong>Assistant Professor, Bryant University<br \/>\n<\/strong>Dr. Kristin Scaplen graduated from the University of Connecticut with a B.Sc in Biology and a B.Sc in Psychology. She received her PhD from Brown University in Neuroscience under the mentorship of Dr. Rebecca Burwell (who has served as a RI-INBRE faculty mentor) and then completed a postdoc, also at Brown, under the mentorship of Dr. Karla Kaun, a former RI-INBRE investigator who was funded by COBRE at the time of Dr. Scaplen\u2019s postdoc.&nbsp; Dr. Scaplen&#8217;s&nbsp; research background is quite broad but rooted in understanding neural circuitry mechanisms underlying learning and memory. She started studying this in rodents as an undergraduate and graduate student and moved to the Drosophila model during her postdoc, largely because of the impressive neurogenetic tools available in flies that permit dissection of circuits underlying complex behavior with unprecedented temporal and spatial resolution.&nbsp;<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-30287 size-medium\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Scaplan_Rauff-Taryn-2021-SURF-C-300x236.jpg\" alt=\"\" width=\"300\" height=\"236\">She is particularly interested in understanding how learning and memory processes are disrupted by drugs of abuse to drive maladaptive behaviors. As a postdoc, she defined local circuits that were important for the acquisition, consolidation, and expression of alcohol reward and identified downstream structures\/subsets of neurons where these circuits converge. \u201cMy fascination with the brain began in a lecture hall as an undergraduate when I took an Introduction to Neuroscience class,\u201d she says. \u201cWhen I realized how much we still don\u2019t know about the brain and the fact that people were actively trying to broaden our knowledge, I knew it was something I wanted to do. The idea of contributing to our understanding of the brain and improving the human condition was really exciting to me.\u201d The focus of her current work is to define the role of these downstream structures in alcohol reward memories and understand how circuitry dynamics change while flies learn to associate cues with alcohol intoxication to result in long-lasting preferences.&nbsp;<br \/>\nDr. Scaplen is excited to bring Neuroscience to the Bryant community and engage undergraduates in the research process and is looking forward to expanding her own research network and form new collaborations within the RI-INBRE community. \u201cBryant\u2019s mission places emphasis on developing innovating leaders. In science, innovative ideas are the foundation of discovery and there is still a lot to discover and understand,\u201d she says. \u201cI hope to inspire students to see themselves as active contributors to science. The health sciences field will only benefit from diverse perspectives and ideas.\u201d<\/p>\n<hr>\n<p><strong>&#8220;Identifying and quantifying drug metabolism by the human gut microbiome.&#8221; <\/strong><strong>Dr. Tyler Stack, Assistant Professor of Chemistry and Biochemistry, Providence College<img loading=\"lazy\" decoding=\"async\" class=\"size-medium wp-image-27620 alignright\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/Stack-lab-237x300.jpg\" alt=\"\" width=\"237\" height=\"300\"><br \/>\n<\/strong>Dr. Tyler Stack received his bachelor&#8217;s degree in Chemistry at the University of Minnesota\u2013Twin Cities and worked in Dr. Marc Hillmyer&#8217;s lab making &#8220;green&#8221; monomers to create biodegradable plastics. He learned that an enzyme could perform the exact reaction he wanted and became interested in how enzymes can catalyze reactions. \u201cAs part of my undergraduate thesis, I wanted a catalyst to perform a green oxidation reaction, with goals to occur in water, at room temperature, and with no toxic chemicals,\u201d he says. \u201cI found an enzyme that performed my exact reaction in water at room temperature, using molecular oxygen as the oxidant. A catalyst doesn&#8217;t get much better than an enzyme, and I was upset that I had no idea how to get that enzyme and use it as a catalyst.\u201d He attended the University of Texas at Austin for his Ph.D. in Biochemistry working with Dr. Chris Whitman to study the bacterial catabolism of halogenated aromatic compounds. Dr. Stack had a postdoctoral research position with Dr. John Gerlt at the University of Illinois at Urbana-Champaign where he focused on large-scale bacterial enzyme functional assignments, including discovering and characterizing a catabolic pathway for Vitamin C in bacteria.<br \/>\n<img loading=\"lazy\" decoding=\"async\" class=\"alignleft wp-image-30279 size-third_column\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-364x243.jpg\" alt=\"\" width=\"364\" height=\"243\" srcset=\"https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-364x243.jpg 364w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-300x200.jpg 300w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-1024x683.jpg 1024w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-768x512.jpg 768w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-1536x1024.jpg 1536w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-2048x1365.jpg 2048w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-500x333.jpg 500w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-1000x667.jpg 1000w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-1280x853.jpg 1280w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-2000x1333.jpg 2000w, https:\/\/web.uri.edu\/riinbre\/wp-content\/uploads\/sites\/1497\/20210730_Salerno_SURFConf-0095-PC-Stack_DeMartino-Jackson-scaled.jpg 2560w\" sizes=\"auto, (max-width: 364px) 100vw, 364px\" \/>Dr. Stack\u2019s research career has been centered around his interest in how enzymes work and discovering their function. As a graduate student, he noticed the growing interest and tools to investigate the human gut microbiome. Given the disparity between bacterial genomic sequencing and the functional annotation to confidently predict their metabolism, he became fascinated with the gut microbiome&#8217;s diversity and dynamic composition, along with their direct impact on human health. \u201cThe trillions of microbes that inhabit our guts help metabolize the food we eat, and this metabolism can be specific or promiscuous to respond to our changing diets,\u201d he says. \u201cWe need enzymes to be specific, and the best example is DNA polymerase. Making errors generally leads to cell death and cancer in our cells. No enzyme is perfect, and mistakes have to be rectified by our many DNA repair enzymes. However, there needs to be some promiscuity because there would be no evolution without errors in DNA polymerase!\u201d Most of the enzymes in these bacteria are of unknown function, and his current research interests focus on the promiscuity of enzymes and the metabolic &#8220;mischief&#8221; they can incur on us as their hosts. His ECD research project focuses on this &#8220;accidental&#8221; metabolism by bacteria in the human gut and how they change the structure of the drugs we ingest. Although the function of an enzyme is not likely to metabolize a specific drug, a growing field of research identifies drug-metabolizing enzymes found in gut bacteria. \u201cEnzymatic promiscuity has consequences when it comes to how our gut microbiome changes the efficacy of cancer therapeutics. One example is the deglycosylation of the anticancer drug capecitabine<\/p>\n<\/div>\n","protected":false},"excerpt":{"rendered":"<p>A Warm Welcome to&nbsp; Dr. Lindsay Green-Gavrielidis, Salve Regina University Dr. Kristin Scaplen, Bryant University Dr. Tyler Stack, Providence College \u201cAssessing the impact of harmful macroalgal blooms on costal environmental health.\u201d Dr. Lindsay Green-Gavrielidis, Assistant Professor, Salve Regina University The goal of Dr. Green-Gavrielidis\u2019 ECD project is assessing the impacts of harmful macroalgal blooms on [&hellip;]<\/p>\n","protected":false},"author":1036,"featured_media":27625,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[636],"tags":[615,295,606,620],"class_list":["post-27584","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-old-enews-posts","tag-drpp","tag-ecd-awards","tag-enews","tag-green-gavrielidis"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts\/27584","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/users\/1036"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/comments?post=27584"}],"version-history":[{"count":5,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts\/27584\/revisions"}],"predecessor-version":[{"id":31078,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts\/27584\/revisions\/31078"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/media\/27625"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/media?parent=27584"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/categories?post=27584"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/tags?post=27584"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}