{"id":31799,"date":"2022-02-21T13:56:58","date_gmt":"2022-02-21T18:56:58","guid":{"rendered":"https:\/\/web.uri.edu\/riinbre\/?p=31799"},"modified":"2022-02-25T12:47:32","modified_gmt":"2022-02-25T17:47:32","slug":"methotrexate-vr","status":"publish","type":"post","link":"https:\/\/web.uri.edu\/riinbre\/methotrexate-vr\/","title":{"rendered":"Methotrexate VR"},"content":{"rendered":"<p><section class=\"cl-wrapper cl-panel-wrapper\"><div class=\"cl-panel reverse  \"><figure><img decoding=\"async\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/methotrexate_frame1.jpg\" srcset=\"\" alt=\"\"><\/figure><article><h1>Methotrexate VR<\/h1><p>Exploring the history, clinical applications and pharmacology of aspirin in virtual reality.<\/p><\/article><\/div><\/section>Methotrexate is a folate inhibitor that targets the dihydrofolate reductase (DHFR) enzyme, resulting in interference with nucleotide synthesis and cellular repair.&nbsp; For this reason, methotrexate is used as an anti-cancer drug.&nbsp; The goal of this app is to demonstrate the activity of methotrexate when interacting with DHFR in a virtual environment that requires the user to interact with the molecules.&nbsp; From the technical perspective, this was the first app where we experimented with molecular animations, in-app quizzes, and text-to-voice capabilities.<\/p>\n<p>&nbsp;<\/p>\n<div class=\"cl-tiles halves\"><div class=\"cl-wrapper cl-card-wrapper\"><a class=\"cl-card   left\" href=\"https:\/\/web.uri.edu\/riinbre\/?p=31799&amp;preview=true\" title=\"\"><div class=\"cl-card-container media\"><img decoding=\"async\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/methotrexate_5.gif\" srcset=\"\" alt=\"Methotrexate App Example 1\"><\/div><div class=\"cl-card-container text\"><\/div><\/a><\/div><div class=\"cl-wrapper cl-card-wrapper\"><a class=\"cl-card   left\" href=\"https:\/\/web.uri.edu\/riinbre\/?p=31799&amp;preview=true\" title=\"\"><div class=\"cl-card-container media\"><img decoding=\"async\" src=\"https:\/\/web.uri.edu\/wp-content\/uploads\/sites\/1497\/methotrexate_frame2.jpg\" srcset=\"\" alt=\"Methotrexate App Example 2\"><\/div><div class=\"cl-card-container text\"><\/div><\/a><\/div><\/div>\n","protected":false},"excerpt":{"rendered":"<p>Methotrexate is a folate inhibitor that targets the dihydrofolate reductase (DHFR) enzyme, resulting in interference with nucleotide synthesis and cellular repair.&nbsp; For this reason, methotrexate is used as an anti-cancer drug.&nbsp; The goal of this app is to demonstrate the activity of methotrexate when interacting with DHFR in a virtual environment that requires the user [&hellip;]<\/p>\n","protected":false},"author":3192,"featured_media":0,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[682],"tags":[256,683,679,650],"class_list":["post-31799","post","type-post","status-publish","format-standard","hentry","category-virtual-and-augmented-reality-apps-developed-at-the-mic-sta","tag-cancer","tag-methotrexate","tag-virtual-reality","tag-vr"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts\/31799","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/users\/3192"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/comments?post=31799"}],"version-history":[{"count":5,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts\/31799\/revisions"}],"predecessor-version":[{"id":31819,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/posts\/31799\/revisions\/31819"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/media?parent=31799"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/categories?post=31799"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.uri.edu\/riinbre\/wp-json\/wp\/v2\/tags?post=31799"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}