{"id":11138,"date":"2016-03-24T13:42:53","date_gmt":"2016-03-24T17:42:53","guid":{"rendered":"https:\/\/web.uri.edu\/rinsfepscor\/?p=11138"},"modified":"2016-03-24T13:42:53","modified_gmt":"2016-03-24T17:42:53","slug":"rwu-researcher-contributes-veterinary-expertise","status":"publish","type":"post","link":"https:\/\/web.uri.edu\/rinsfepscor\/2016\/03\/24\/rwu-researcher-contributes-veterinary-expertise\/","title":{"rendered":"RWU researcher contributes veterinary expertise"},"content":{"rendered":"

\"Roxanna<\/a>Roxanna Smolowitz<\/strong>
\nRoger Williams Universit<\/a>y<\/strong>
\nAssistant professor; biology, marine biology<\/strong>
\nDirector, Aquatic Diagnostic Laboratory<\/a><\/strong>
\nSURF<\/a> program mentor<\/strong><\/p>\n

\n

Rhode Island STAC<\/a> awards<\/h3>\n

2012 STAC grant: New Tools and Mechanisms to Combat Aquaculture Diseases. <\/strong>The project sought\u00a0to develop new tools to promote animal health in aquaculture by building on recent discoveries of marine bacteria that demonstrate impressive protective properties against disease. The objective was to develop new commercial products to promote fitness and prevent disease for finfish and shellfish in aquaculture facilities.
\nCollaborators:<\/strong> David Rowley, David Nelson and Marta Gomez-Chiarri, URI; Dale Leavitt and Roxanna Smolowitz, RWU<\/p>\n

\n

2013 STAC grant: The Pathogenic Cause and Impact of the Local Sea Star Wasting Disease.<\/strong> Starfish from New Jersey to the Gulf of Maine fell victim to a mysterious and deadly infectious disease. This collaboration brought\u00a0together six researchers from three institutions with ecological, veterinary, molecular, microbial, and aquaculture expertise to identify what pathogen caused\u00a0these deaths before it could\u00a0spread to additional species in the marine environment.
\nCollaborators<\/strong>: Gary Wessel, Brown University; Roxanna Smolowitz, RWU; Marta Gomez-Chiarri, URI; Edward Baker, URI<\/p>\n

\n

2014 STAC grant: Molecular Basis for Pathogenesis in the Oyster Pathogen, Roseovarius Crassostreae.<\/strong> Oyster aquaculture is expanding in Narragansett Bay, but this economic endeavor is threatened by a variety of pathogenic infectious agents including the causative agent of Roseovarius oyster disease (ROD). Warming waters that stress the host have led to devastating ROD outbreaks, which have resulted in some cases in losses of oyster seed of greater than 90 percent. This project combined the talents of a molecular biologist, a natural products chemist and a shellfish pathologist to seek a better understanding of ROD in order to better manage the disease.
\nCollaborators:<\/strong> David Nelson, URI; David Rowley, URI; Roxanna Smolowitz, RWU<\/p>\n

\n

2015 STAC grant: Marine Disturbance Disease and Climate Change in Rhode Island’s Coastal Waters \u2014 <\/strong>Merging Higher Trophic Level Population Dynamics Models\/Datasets with Lower Trophic Level Climate Forecast Models. This team will use physical oceanography and aquatic pathology to integrate historic datasets to understand the relationship between physical and chemical changes in the ocean and various health issues affecting coastal fish and shellfish of commercial interest.
\nCollaborators:<\/strong> Lewis Rothstein, URI GSO; Kathleen Castro, URI; Marta Gomez-Chiarri, URI; Roxanna Smolowitz, RWU<\/p>\n<\/div>\n

If there is an EPSCoR research project in Rhode Island investigating the health or disease of marine animals, there is a good chance Roxanna Smolowitz is involved.<\/p>\n

\"\"<\/a>With deep expertise in aquatic veterinary science, Smolowitz regularly teams up with her colleagues at EPSCoR partner institutions, from developing tools to combat aquaculture disease to seeking answers to a mysterious and prolonged sea star die off.<\/p>\n

\u201cWithout collaboration, it wouldn\u2019t be anywhere near possible to do what we do. That accessibility and interactions with other professors is critical.\u201d<\/p><\/blockquote>\n

In her first RI Science and Technolocy Council (STAC) grant, in 2012, Smolowitz collaborated with URI professors David Rowley, David Nelson, and Marta Gomez-Chiarri on using marine bacteria as a protective agent against disease.<\/p>\n

\u201cThe idea was, are there different kinds of bacteria we could add to larval cultures of bivalves specific to oysters to increase healthiness and get more animals through the metamorphosis stage,\u201d explains Smolowitz, noting that one Vibrio<\/em> bacterial disease, in particular, is responsible for high rates of larval death.<\/p>\n

The scientists identified two bacteria that might provide a protective defense as probiotics, developed varying concentrations and methods of application, treated larvae in different tanks, and observed morbidity, mortality, survival, and growth rates. With the STAC award serving as seed funding for the project, the team secured follow-on grants to test the potential of the results and now will see if the findings hold true for different bivalves and application methods, and move from experimental, controlled research to out in the field.<\/p>\n

Assessing the process and outcomes to date, Smolowitz reflects: \u201cI don\u2019t think this work would have been accomplished if we had not worked together. A lot of collaboration was needed to pull it off.<\/p>\n

\u201cAnd, the result is that we have two potential bacteria that might be usable in commercial hatcheries; it\u2019s producing a product, hopefully, and lots more questions. When you see a result, you need to know why it\u2019s happening.\u201d<\/p>\n

A 2013 STAC grant pulled together a multi-disciplinary team to pursue answers to a prolonged and unexplained die off of sea stars from New Jersey to the Gulf of Maine. The history of such disease in marine animals is episodic, periodically waxing and waning, notes Smolowitz, but the most recent outbreak was surprisingly long and lethal.<\/p>\n

A massive die off took place along the Pacific shoreline at the same time, but Smolowitz, who worked on the histology, or tissue, angle of the disease, says no one was addressing the issue here. Ultimately, in 2014, scientists reported that a sea star associated densovirus (SSaDV) was at the root of the West Coast deaths. But, questions remain whether there was any relation between the incidences on both coasts.<\/p>\n

\u201cWe\u2019re still investigating it and thinking about where we might go next,\u201d Smolowitz says. \u201cMore work needs to be done. Climate change could be one of the reasons why the episode lasted so long. Lots of things are happening out there that we don\u2019t really understand.\u201d<\/p>\n

Even though the New England outbreak lacks a definitive cause at the moment, the STAC project produced valuable data, according to Smolowitz: \u201cThis disease has happened in groups of echinoderms around the world. Many more scientists and lay people are aware of it now. The problem is documented in the literature, so we\u2019ve got a base of findings and tissues to refer to. That didn\u2019t happen last time this occurred. This current material and information will provide material to build on in future outbreaks.\u201d<\/p>\n

Smolowitz also is contributing her expertise to a 2015 STAC grant integrating historical datasets with numerical models to better understand how physical and chemical changes in the ocean impact the health of coastal fish and shellfish.<\/p>\n

For her part, Smolowitz is collecting data on bivalve disease to add into the models and see if any patterns emerge. She says she finds the project fascinating in the perspective it takes, looking at the way the water moves and how that information can fit and overlay with the biological data.<\/p>\n

Throughout all of the projects, Smolowitz says, RI EPSCoR core facilities and equipment provide support, without which the work would not be possible. For example, the RI Genomics and Sequencing Center<\/a> at URI, makes procedures \u2014 identifying a parasite in blue mussels \u2014\u00a0accessible and affordable.<\/p>\n

She also says the breadth and depth of the EPSCoR community of scientists offers a knowledge base that builds on what is available on individual campuses: \u201cWithout collaboration, it wouldn\u2019t be anywhere near possible to do what we do. That accessibility and interactions with other professors is critical.\u201d<\/p>\n

Story and photo by Amy Dunkle | RI NSF EPSCoR<\/em><\/p>\n","protected":false},"excerpt":{"rendered":"

Roxanna Smolowitz Roger Williams University Assistant professor; biology, marine biology Director, Aquatic Diagnostic Laboratory SURF program mentor Rhode Island STAC awards 2012 STAC grant: New Tools and Mechanisms to Combat Aquaculture Diseases. The project sought\u00a0to develop new tools to promote animal health in aquaculture by building on recent discoveries of marine bacteria that demonstrate impressive […]<\/p>\n","protected":false},"author":2,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":"","_links_to":"","_links_to_target":""},"categories":[21,1,63],"tags":[96,570,585,597,630,741],"class_list":["post-11138","post","type-post","status-publish","format-standard","hentry","category-news","category-uncategorized","category-we-are-ri-epscor","tag-aquaculture","tag-rhode-island-nsf-epscor","tag-ri-stac","tag-roger-williams-university","tag-sea-star-disease","tag-university-of-rhode-island"],"acf":[],"_links":{"self":[{"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/posts\/11138","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/users\/2"}],"replies":[{"embeddable":true,"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/comments?post=11138"}],"version-history":[{"count":0,"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/posts\/11138\/revisions"}],"wp:attachment":[{"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/media?parent=11138"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/categories?post=11138"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/web.uri.edu\/rinsfepscor\/wp-json\/wp\/v2\/tags?post=11138"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}