{"id":8,"date":"2025-12-19T10:23:56","date_gmt":"2025-12-19T15:23:56","guid":{"rendered":"https:\/\/web.uri.edu\/ross-lab\/?page_id=8"},"modified":"2025-12-19T10:23:57","modified_gmt":"2025-12-19T15:23:57","slug":"publications","status":"publish","type":"page","link":"https:\/\/web.uri.edu\/ross-lab\/publications\/","title":{"rendered":"Publications"},"content":{"rendered":"\n
(\u266f<\/sup>) Corresponding author
(\u2020<\/sup>) signifies trainees <\/h6>\n\n\n\n

Select Publications<\/h2>\n\n\n\n
\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Mitochondrial Dysfunction: A Key Player in Brain Diseases. Bartman S*, Coppotelli G*, Ross JM*. Current Issues in Molecular Biology<\/a><\/strong><\/em>, February 2024.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Mitochondrial Dysfunction and Protein Homeostasis in Aging: Insights from a Premature-Aging Mouse Model. Ross JM*, Olson L, Coppotelli G*. MDPI<\/a><\/strong><\/em>, January 2024.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Gaspar L*, Bartman S*, Coppotelli G*, Ross J*. Effect of apparatus characteristics on anxiety-like behavior in young adult and old mice of both sexes assessed by the elevated plus maze assay. Frontiers in Behavioral Neuroscience<\/a><\/strong><\/em>, August 2023.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Gaspar L*, Bartman S*, Coppotelli G*, Ross J*. Acute Exposure to Microplastics Induced Changes in Behavior and Inflammation in Young and Old Mice. International Journal of Molecular Science<\/a><\/strong><\/em>, August 2023.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

\u201cMitochondria in Aging and Diseases: Partie Deux,\u201d Tobias-Wallingford H<\/strong>, Coppotelli G<\/strong>, Ross JM<\/strong>. International Journal of Molecular Sciences<\/a><\/strong><\/em>, June 2023. <\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n


Yang J-H et al (including Ross JM<\/strong>, Coppotelli G<\/strong>). Loss of epigenetic information as a cause of mammalian aging. Cell<\/a>,<\/em><\/strong> Jan 2023.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n


Amorim J, Coppotelli G<\/strong>, Rolo A, Palmeira C, Ross JM<\/strong>, Sinclair D. (2021). Mitochondrial and metabolic dysfunction in ageing and age-related diseases. Nature Reviews Endocrinology<\/a>,<\/em><\/strong> Feb 2022.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n


Adel\u00f6f J, Ross JM<\/strong>, Zetterberg M, Hernebring M. (2021). Survival-Span Method: How to Qualitatively Estimate Lifespan to Improve the Study of Aging, and not Disease, in Aging Studies. Frontiers in Aging<\/a>,<\/em><\/strong> Dec 2021.<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Potts E\u2020, Coppotelli G<\/strong>, Ross JM<\/strong>#. (2020) Histological-based stainings using free-floating method. Journal of Visualized Experiments. Jove<\/a><\/strong><\/em>, DOI: 10.3791\/61622.
<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Adel\u00f6f J, Ross JM<\/strong>, Lazic SE, Zetterberg M, Wiseman JW, Hernebring M. (2019). Conclusions from a behavioral aging study on male and female F2 hybrid mice on age-related behavior, buoyancy in water-based tests, and an ethical method to assess lifespan. Aging,<\/em><\/strong>Sep 11;11(17):7150-7168. PubMed<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM\u266f<\/sup>, Coppotelli G\u266f<\/sup><\/strong>,Branca RM, Kim KM\u2020<\/sup><\/strong>, Lehti\u00f6 J, Sinclair DA, Olson L. (2019). Voluntary exercise normalizes the proteomic landscape in muscle and brain and improves the phenotype of progeroid mice. Aging Cell, <\/em><\/strong>Dec;18(6):e13029. PubMed<\/a>
<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM<\/strong>, Coppotelli G<\/strong>, Olson L (Eds). (2016).Mitochondrial Dysfunction in Ageing and Diseases. International Journal of Molecular Sciences. <\/strong>Basel: MDPI AG.<\/a>ISBN: 978-3-03842-251-8<\/p>\n\n\n\n

Coppotelli G<\/strong>, Ross JM\u266f<\/sup>.<\/strong>(2016). Mitochondria in Ageing and Diseases: The Super Trouper of the Cell. International Journal of Molecular Sciences<\/em><\/strong>, Special Issue, \u201cMitochondrial Dysfunction in Ageing and Diseases\u201d. 17(5):711. DOI: PubMed<\/a> (invited Editorial)
<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"IJMS<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM\u266f<\/sup><\/strong>, Olson L, Coppotelli G<\/strong>#<\/sup>. (2015). The Mitochondrial and Ubiquitin Proteasome Systems in ageing and disease: Two sides of the same coin? International Journal of Molecular Sciences<\/em><\/strong>, Special Issue, \u201cMitochondrial Dysfunction in Ageing and Diseases\u201d. 16(8):19458-76. DOI:10.3390\/ijms160819458 PubMed<\/a>(invited review)<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM\u266f<\/sup><\/strong>, Coppotelli G<\/strong>, Hoffer BJ, Olson L. (2014). Maternally transmitted mtDNA mutations cause reduced lifespan. Scientific Reports<\/em><\/strong>,4, 6569; DOI:10.1038\/srep06569. PubMed<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM, <\/strong>Stewart JB, Hagstr\u00f6m E, Bren\u00e9 S, Mourier A, Coppotelli G<\/strong>, Freyer C, Lagouge M, Hoffer BJ, Olson L, Larsson NG. (2013). Germline mtDNA mutations aggravate ageing and can impair brain development. Nature<\/em><\/strong>, Sep 19; 501(7467): 412-5. PMID:23965628  PubMed<\/a><\/p>\n\n\n\n

*<\/strong>Commented by:Keogh M and Chinnery PF (2013). Hereditary mtDNA Heteroplasmy: A Baseline for Aging? Cell Metabolism<\/em><\/strong>,<\/em>Oct 1; 18(4): 463-4. PMID:24093673 PubMed<\/a><\/p>\n\n\n\n

*Commented by:Burgess DJ (2013). Disease genetics: Double danger from mitochondrial mutations. Nature Reviews Genetics<\/em><\/strong>,<\/em>Oct ;14(10): 678-9. PMID:    24022701 PubMed<\/a><\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"Jove<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM\u266f<\/sup>. <\/strong>(2011). Visualization of mitochondrial respiratory function using cytochrome c <\/em>oxidase \/ succinate dehydrogenase (COX\/SDH) double-labeling histochemistry. Journal of Visualized Experiments<\/em><\/strong>, <\/em>(57): e3266, DOI: 10.3791\/3266.<\/em>PMID: 22143245 PubMed<\/a>(invited by Editor)<\/p>\n<\/div>\n<\/div>\n\n\n\n

\n
\n
\"\"<\/figure>\n<\/div><\/div>\n\n\n\n
\n

Ross JM\u266f<\/sup>, <\/strong>\u00d6berg J, Bren\u00e9 S, Coppotelli G<\/strong>, Terzioglu M, Pernold K, Goiny M, Sitnikov R, Kehr J, Trifunovic A, Larsson NG, Hoffer BJ and Olson L. (2010). High brain lactate is a hallmark aging and caused by a shift in the lactate dehydrogenase A\/B ratio. Proceedings of the National Academy of Sciences of the United States of America<\/em><\/strong>, <\/em>Nov 16; 107(46): 20087-92. PMID: 21041631 PubMed<\/a><\/p>\n<\/div>\n<\/div>\n\n\nfull list of publications<\/a>\n\n\n

\n\n\n

In the News<\/h1>\n\n

“Acute Exposure to Microplastics Induced Changes in Behavior and Inflammation in Young and Old Mice”<\/strong><\/p>\n\n\n\n