Alan L. Rothman


MD, Research Professor

Head, Laboratory of Viral Immunity and Pathogenesis
Program Director, URI/RIH COBRE in infectious diseases immunology
Office: FCCE Room 302D
Telephone: (401) 277-5419

  • B.A., Boston University
  • M.D., Boston University School of Medicine
  • CMB333 – Immunology and Serology

Dr. Rothman has been involved in research on immunity and pathogenesis of viral diseases in humans for over 25 years. A major focus of his research has been defining the virological and immunological events in acute dengue virus infection and their relationship to the development of the viral hemorrhagic fever syndrome. Dr. Rothman has long-standing collaborations with colleagues at the University of Massachusetts, Walter Reed Army Institute of Research, and internationally in Thailand, Europe, and Latin America. His current studies involve both clinical and basic research studies on pathogenesis and immunity of emerging and re-emerging viral infections. Dr. Rothman has served on advisory committees for the National Institutes of Health and the World Health Organization.

Dr. Rothman serves as Program Director for the Dengue Hemorrhagic Fever Project, an international collaboration involving research in Thailand and the Philippines funded by the National Institute of Allergy and Infectious Diseases. He also has ongoing collaborations with investigators in South America. Laboratory studies at URI examine dengue viral replication, cellular responses to infection, and antibody and T lymphocyte responses to natural dengue virus infection and immunization.

Dr. Rothman is also Program Director for a phase I COBRE (Center of Biomedical Research Excellence), “Immune-based Interventions against Infectious Diseases,” funded by the National Institute of General Medical Sciences. This research program, a joint effort with the Center for International Health Research at Rhode Island Hospital, supports translational research projects in the immunology of infectious diseases of global health importance, including dengue, HIV, and malaria.