Publications and Patents

Peer-reviewed publications

Articles with URI affiliation

  • Nadeem, A.; Lyons, S.; Kindopp, A.; Jamieson, A.; Roxbury, D. “Machine Learning-Assisted Near-Infrared Spectral Fingerprinting for Macrophage Phenotyping” ACS Nano 2024, 18, 34, 22874.
  • Nadeem, A.*; Kindopp, A.*; Wyllie, I.; Hubert, L.; Joubert, J.; Lucente, S.; Randall, E.; Jena, P.V.; Roxbury, D. “Enhancing Intracellular Optical Performance and Stability of Engineered Nanomaterials via Aqueous Two-Phase Purification” Nano Lett. 2023, 23, 14, 6588. (* designates co-first)
  • Roger, L.; Lewinski, N.; Putnam, H.; Roxbury, D.; Tresguerres, M.; Wangpraseurt, D. “Nanobiotech engineering for future coral reefs” One Earth 2023, 6, 778. 
  • Roger, L.; Lewinski, N.; Putnam, H.; Chen, S.; Roxbury, D.; Tresguerres, M.; Wangpraseurt, D. “Nanotechnology for coral reef conservation, restoration and rehabilitation” Nature Nanotechnology 2023, 18, 831.
  • Gravely, M.; Kindopp, A.; Hubert, L.; Card, M.; Nadeem, A.; Miller, C.; Roxbury, D. “Aggregation Reduces Subcellular Localization and Cytotoxicity of Single-Walled Carbon Nanotubes” ACS Appl. Mat. Int. 2022, 14, 17, 19168.
  • Jena, P.V.; Gravely, M.; Cupo, C.; Safaee, M.M.; Roxbury, D.*; Heller, D.A.* “Hyperspectral Counting of Multiplexed Nanoparticle Emitters in Single Cells and Organelles” ACS Nano 2022, 16, 2, 3092. (* co-corresponding author)
  • Langenbacher, R.; Budhathoki-Uprety, J.; Jena, P.V.; Roxbury, D.; Streit, J.; Zheng, M.; Heller, D.A. “Single-Chirality Near-Infrared Carbon Nanotube Sub-Cellular Imaging and FRET Probes” Nano Lett. 2021, 21, 15, 6441.
  • Gravely, M.; Roxbury, D. “Multispectral Fingerprinting Resolves Dynamics of Nanomaterial Trafficking in Primary Endothelial Cells” ACS Nano 2021, 15, 7, 12388.
  • Card, M.; Gravely, M.; Madani, S.Z.M.; Roxbury, D. “A Spin-Coated Hydrogel Platform Enables Accurate Investigation of Immobilized Individual Single-Walled Carbon Nanotubes” ACS Appl. Mater. Int. 2021, 13, 27, 31986.
  • Safaee, M.M.; Gravely, M.; Roxbury, D. “A Wearable Optical Microfibrous Biomaterial with Encapsulated Nanosensors Enables Wireless Monitoring of Oxidative Stress” Adv. Funct. Mater. 2021, 31, 13, 2006254. 
  • Madani, S.Z.M.; Safaee, M.M.; Gravely, M.; Silva, C.; Kennedy, S.M.; Bothun, G.D.; Roxbury, D. “Carbon Nanotube–Liposome Complexes in Hydrogels for Controlled Drug Delivery via Near-Infrared Laser Stimulation” ACS Appl. Nano Mater. 2021, 4, 1, 331.
  • Heller, D.A.; Jena, P.V.; Pasquali, M.; Kostarelos, K.; Delogu, L.G.; Meidl, R.E.; Rotkin, S.V.; Scheinberg, D.A.; Schwartz, R.E.; Terrones, M.; Wang, Y.; Bianco, A.; Boghossian, A.A.; Cambre, S.; Cognet, L….Roxbury, D. et al. “Banning carbon nanotubes would be scientifically unjustified and damaging to innovation” Nature Nanotechnology, 2020, 15, 164.
  • Madani, S. Zahra M.; Reisch, A.; Roxbury, D., Kennedy, S.M. “A Magnetically Responsive Hydrogel System for Controlling the Timing of Bone Progenitor Recruitment and Differentiation Factor Deliveries” ACS Biomater. Sci. Eng. 2020, 6, 3, 1522. 
  • Gravely, M.; Safaee, M.M.; Roxbury, D. “Biomolecular Functionalization of a Nanomaterial to Control Stability and Retention within Live Cells” Nano Lett. 2019, 19, 9, 6203. 
  • Safaee, M.M.; Gravely, M.; Lamothe, A.; McSweeney, M.; Roxbury, D. “Enhancing the Thermal Stability of Carbon Nanomaterials with DNA” Sci. Rep. 2019, 9, 11926. 
  • Safaee, M.M.; Gravely, M.; Rocchio, C.; Simmeth, M.; Roxbury, D. “DNA Sequence Mediates Apparent Length Distribution in Single-Walled Carbon Nanotubes” ACS Appl. Mater. Int. 2019, 11, 2, 2225. 
  • Galassi, T.V.; Jena, P.V.; Shah, J.; Ao, G.; Molitor, E.; Bram, Y.; Frankel, A.; Park, J.; Jessurun, J.; Ory, D.S.; Haimovitz-Friedman, A.; Roxbury, D.; Mittal, J.; Zheng, M.; Schwartz, R.E.; Heller, D.A. “An optical nanoreporter of endolysosomal lipid accumulation reveals enduring effects of diet on hepatic macrophages in vivo” Science Transl. Med. 2018, 10, 461. 
  • Shamay, Y.; Shah, J.; Işık, M.; Mizrachi, A.; Leibold, J.; Tschaharganeh, D.F.; Budhathoki-Uprety, J.; Nawaly, K.; Sugarman, J.L.; Baut, E.; Neiman, M.R.; Dacek, M.; Ganesh, K.S.; Johnson, D.C.; Sridharan, R.; Chu, K.L.; Rajasekhar, V.K.; Roxbury, D.; Lowe, S.W.; Chodera, J.D.; Heller, D.A. “Quantitative Self Assembly Prediction Yields Targeted Nanomedicines” Nature Materials 2018, 17, 4, 361. 
  • Jena, P.V.*; Roxbury, D.*; Galassi, T.V.*; Akkari, L.; Horoszko, C.P.; Iaea, D.B.; Budhathoki-Uprety, J.; Pipalia, N.; Haka, A.S.; Harvey, J.D.; Mittal, J.; Maxfield, F.R.; Joyce, J.A.; Heller, D.A. “A Carbon Nanotube Optical Reporter Maps Endolysosomal Lipid Flux” ACS Nano 2017, 11, 11, 10689. (* designates co-first)
  • Jena, P.V.; Safaee, M.M.; Heller, D.A.; Roxbury, D. “DNA–Carbon Nanotube Complexation Affinity and Photoluminescence Modulation Are Independent” ACS Appl. Mater. Int. 2017 9, 25, 21397.
  • Budhathoki-Uprety, J.; Langenbacher, R.E.; Jena, P.V.; Roxbury, D.; Heller, D.A. “A Carbon Nanotube Optical Sensor Reports Nuclear Entry via a Non-Canonical Pathway ” ACS Nano 2017, 11, 4, 3875.
  • Harvey, J.D.; Jena, P.V.; Baker, H.A.; Zerze, G.H.; Williams, R.M.; Galassi, T.V.; Roxbury, D.; Mittal, J.; Heller, D.A. “A Carbon Nanotube Reporter of miRNA Hybridization Events In Vivo” Nature Biomed. Eng. 2017, 1, 0041.
  • Galassi, T.V.; Jena, P.V.; Roxbury, D.; Heller, D.A. “Single Nanotube Spectral Imaging To Determine Molar Concentrations of Isolated Carbon Nanotube Species”  Anal. Chem. 2017, 89, 2, 1073.
  • Jena, P.V.; Galassi, T.V.; Roxbury, D.; Heller, D.A. “Review—Progress toward Applications of Carbon Nanotube Photoluminescence” ECS J. Solid State Sci. Technol. 2017, 6, 6, M3075.

Articles with previous affiliations

  • Roxbury, D.; Jena, P.V.; Shamay, Y.; Horoszko, C.P.; Heller, D.A. “Cell Membrane Proteins Modulate the Carbon Nanotube Optical Bandgap via Surface Charge Accumulation” ACS Nano 2016, 10, 1, 499.
  • Jena, P.V.; Shamay, Y.; Shah, J.; Roxbury, D.; Paknejad, N.; Heller, D.A. “Carbon Nanotube Fluorescence Resolves the Permeability of Multicellular Tumor Spheroids” Carbon 2016, 97, 99.
  • Roxbury, D.*; Jena, P.V.*; Williams, R.M.; Balazs, E.; Niethammer, P.; Marcet, S.; Verhaegen, M.; Blais-Ouellette, S.; Heller, D.A. “Hyperspectral Microscopy of Near-Infrared Fluorescence Enables 17-Chirality Carbon Nanotube Imaging” Sci. Rep. 2015, 5, 14167. (* designates co-first)
  • Budhathoki-Uprety, J.; Jena, P.V.; Roxbury, D.; Heller, D.A. “Helical Polycarbodiimide Cloaking of Carbon Nanotubes Enables Inter-Nanotube Energy Transfer Modulation” J. Am. Chem. Soc. 2014, 136, 44, 15545.
  • Roxbury, D.; Mittal, J.; DeGrado, W.; Jagota, A. “Structural Stability and Binding Strength of a Designed Peptide-Carbon Nanotube Hybrid” J. Phys. Chem. C 2013, 177, 49, 26255.
  • Roxbury, D.; Jagota, A.; Mittal, J. “Simulated Structural Characteristics of Oligomeric DNA Strands Adsorbed onto Single-Walled Carbon Nanotubes” J. Phys. Chem. B 2013, 117, 1, 132.
  • Bhattacharya, S.; Roxbury, D.; Gong, X.; Mukhopadhyay, D.; Jagota, A. “DNA Conjugated SWCNTs Enter Cells via Rac1 Mediated Macropinocytosis” Nano Lett. 2012, 12, 4, 1826.
  • Roxbury, D.; Mittal, J.; Jagota, A. “Molecular-Basis of Single-Walled Carbon Nanotube Recognition by Single-Stranded DNA” Nano Lett. 2012, 12, 3, 1464.
  • Roxbury, D.; Jagota, A.; Mittal, J. “Sequence Specific Self-Stitching Motif of Short Single-Stranded DNA on a Single-Walled Carbon Nanotube” J. Am. Chem. Soc. 2011, 133, 13545.
  • Roxbury, D.; Tu, X.; Zheng, M.; Jagota, A. “DNA-Carbon Nanotube Recognition Ability Directly Relates to its Binding Strength” Langmuir 2011, 27, 13, 8282.
  • Roxbury, D.; Manohar, S.; Jagota, A. “Molecular Simulation of DNA β-Sheet and β-Barrel Structures on Graphite and Carbon Nanotubes” J. Phys. Chem. C 2010, 114, 31, 13267.

Patents

  • Roxbury, D.; Safaee, M.M.; Gravely, M. “A wearable optical microfibrous biomaterial with encapsulated nanosensors for wireless monitoring of chemical analytes” U.S. Provisional Patent Application No. 63/146,440, Filed 2/5/2021
  • Roxbury, D.; Jena, P.; Heller, D.A. “Composition and Method for Monitoring Lipid” U.S. Patent 10,401,295, Publication Date 9/3/2019