Department of Physics

East Hall, 2 Lippitt Road, Kingston, RI 02881

physics@etal.uri.edu401-874-2104

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John Leith

  • Instructor
  • Email: Cedar_Linne@yahoo.com
  • Office Location: Rhode Island Nuclear Science Center (RINSC)
    16 Reactor Rd.,Narragansett, RI 02882

Biography

2000 – present: Rhode Island Nuclear Science Center, Narragansett, RI.

1996-2002:        Department Chair, Brown University, Adjunct Professor of Chemistry, Brown University, Providence, RI.

1979-2002:        Professor, Department of Biology and Medicine, Brown University, Providence, RI (retired; 2002).

1975-1979:         Associate Professor, University of Arizona Health Sciences Center, University of Arizona, Tucson, AZ.

1973-1974.        Consultant to the United Nations, New York, New York. Preparation of a document on the Effects of Ionizing Radiation on the Nervous system.

1970-1975:        Research Biophysicist, University of California Lawrence Berkeley Laboratory and Donner Laboratory of Medical Physics, University of California, Berkeley, CA.

Education

Ph.D. Major – Physiology and Cellular Biology; Minor – Biochemistry: Boston University, Boston, MA. 1964-1968.

B.A. Major – Biology; Minor – Chemistry: American International College, Springfield, MA. 1959-1964.

Publications

Recent Publications

S. Michelson, J. Leith. Modeling tumor growth, growth factors, and control: what we know, think we know, and wish we knew. Proceedings, 1st World Congress on Computational Medicine, World Scientific Press, 1995.

S. Michelson, Leith. A theoretical explanation of concomitant resistance. Bull Math. Biol. 58, 365-388, 1995.

J. Leith, S. Michelson. Levels of selected growth factors in viable and necrotic regions of xenografted HCT-8 human colon tumors. Cell Prolif. 28, 279-310, 1995.

J. Leith, S. Michelson. Secretion rates and levels of vascular endothelial growth factor in clone A or HCT-8 human colon tumour cells as a functionof oxygen concentration. Cell Prolif. 28, 415-430, 1995.

141. S. Michelson, Leith. Tumor Heterogeneity and growth Control. In: A survey of Models for Tumor-Immune System Dynamics. J. A. Adam, N. Bellom, Eds., Birkhauser, Boston, pp. 295-333, 1997.

S. Michelson, J. Leith. Positive feedback and angiogenesis in tumor growth control. Bull. Math. Biol. 59, 233-254, 1997.

S. Pond-Tor, R.G. Rhodes, P. E. Dahlberg, J. T. Leith, John McMichael, A.E. Dahlberg. Enhancement of radiosensitivity of the MCF-7 breast cancer cell line with human chorionic gonadotropin. Breast Cancer Res., and Therapy, 72, 45-51 2002.

Hercbergs, A.H., Davis, P.J., Davis, F.B., Cieslieski, M., and Leith, J.T., Radiosensitization of GL261 glioma cells by tetraidothyroacetic acid (tetrac). Cell Cycle, 8(16): 2586-2591, 2009. Doi: 10.4161,cc.8.16.9328

Hercbergs, A.H., Lin, H-Y., Davis, F.B., Davis, P.J., and Leith, J.T. Radiosensitization and production of DNA double-strand breaks in U87MG tumor cells induced by tetraiodothyroacetic acid (tetrac). Cell Cycle, 10(2): 352-357, 2011.

Mousa, S.A., Thangirala, S., Yelcin, M., Leith, J.T., Hercbergs, A., Lin, H-Y., Tang, H-Y., Luidens, M.K., and Davis, P.J. Actions of nanoparticle tetraiodiothyroacetic acid (Nanotetrac) in human prostatic carcinoma xenograft growth, vascularity, and integrin responses to radiation. Cancer Res., 74(19 Suppl): 2014. Doi: 10.1158/1538-7445.AM.2014.5378.

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