(1 cr.) Speakers from the Biotech industry will inform students about current research and issues. Students will be able to network for internship placement with speakers. (Seminar) Pre: Biotechnology student

(4 crs.) Introduction to the field of biotechnology including historical development, current technologies and future trends. Molecular and genetic principles and processes used to manipulate living organisms and their products are discussed. (Lec. 3, Lab. 1) Pre: BIO 101 or 110, and 103 or concurrent enrollment.

(3 crs.) Introduction to the field of biotechnology including historical development, current technologies and future trends. Molecular and genetic principles and processes used to manipulate living organisms and their products are discussed. (Lec. 3) Pre: BIO 101 or 110, and 103 or concurrent enrollment.

(1 cr.) This course focuses on foundation knowledge and lab competencies that are critical to success in the biotechnology industry. (Lab. 1) Pre: Biotechnology majors with credit or concurrent enrollment in BTC 110, or by permission of instructor.

(5 crs.) Introduction to biotechnology manufacturing methods including cell culture separation, purification. (Lec. 3, Lab. 4) Pre: Open to Biotechnology majors only. BTC 110.

(1-12 crs.) Professional field experience in biotechnology manufacturing. The experience will be defined by a job description and learning contract arranged by the internship coordinator, student intern and relevant agency. (Practicum) Pre: enrollment in the biotechnology manufacturing option. May be repeated for a maximum of 12 credits.

(3 crs.) This course describes the processes underlying therapeutic drug development for the safe and efficacious treatment of human diseases such as cancer, AIDS, thrombosis and others. (Lec. 3) Pre: BTC (CMB) 110, CMB 211 and 311.

(3 crs.) Cross-listed as (CMB) BTC, MLS 510. This course is designed to teach the principles of laboratory management. The focus is to present underlying managerial concepts and then assist the learner in the successful application of this information to real-life situations. (Online) Pre: Graduate standing or department chair approval.

(3 crs.) This course is designed to provide the student with an overview of the biopharmaceutical manufacturing process. The course will study the process of manufacturing proteins and other large molecules on a large-scale according to current good manufacturing practices (cGMP). Lectures will cover the conceptual aspects of upstream and downstream production issues. (Online) Pre: Graduate standing, or by permission of instructor.

(3 crs.) This course is designed to provide participants with an understanding of the critical role business development and licensing functions play in the commercialization of a discovery product and to the development of a successful biotech company. (Online) Pre: Graduate standing or by permission of instructor.

(3 crs.) Crosslisted as (CMB) BTC/MLS. The course provides advanced applications and laboratory skills needed for molecular diagnostic procedures conducted in biotechnology, clinical and research environments. (Online) Pre: Graduate standing or department chair approval.

(3 crs.) Cross-listed as (AFS), CMB, NRS, PLS 190. Introduction to modern biotechnology in medical, pharmaceutical, forensic, agricultural, marine, and environmental applications. Consideration of ethical, environmental, health, and social issues. (Lec. 3/Online) (A1)

(4 crs.) Required of all students in nursing, dental hygiene, and pharmacy. Lecture and laboratory designed to illustrate microbiological principles and techniques. For students in allied health professions. (Lec. 3, Lab. 3) Pre: one semester of biology and one year of chemistry. Not open to students with credit in CMB 211.

(4 crs.) Introduces the basic concepts and techniques of microbiology. Examines human-microbe relationships and the role that microbes play in health and disease. (Lec. 3, Lab. 3) Suitable for allied health majors.

(3 crs.) Chemistry of biological transformations in the cell. Chemistry of carbohydrates, fats, proteins, enzymes, vitamins and hormones integrated into a general discussion of energy-yielding and biosynthetic reactions in the cell. (Online) Pre: one year college biology and one year of chemistry including CHM 124.

(4 crs.) Introduction to microorganisms. Integrating their morphology, structure, metabolism, genetics, growth, populations in natural habitat, and their effect on the environment. Restricted to certain majors. (Lec. 3, Lab. 1) Pre: One semester of biology, one year of chemistry. Restricted to CELS, nutrition and chemical engineering majors.Not open to students with credit in CMB 201.(D1)

(4 crs.) Introduction to microorganisms. Integrating their morphology, structure, metabolism, genetics, growth, populations in natural habitat, and their effect on the environment. Restricted to certain majors. (Lec. 3, Lab. 1) Pre: One semester of biology, one year of chemistry. Restricted to CELS, neuroscience, and chemical engineering majors. Not open to students with credit in CMB 201.(D1)

(3 crs.) Cross-listed as (CMB) BPS 240. Provide a comprehensive introduction to biomedical research, and will emphasize best practices in experimental design, data management and analysis, biomedical career preparation, and computational skills development. (Lec., Online, Workshop) Pre: BIO 101 or BIO 110 or permission of instructor.

(3 crs.) Basic principles of genetics including patterns of inheritance, mitosis and meiosis, sex determination and sex linkage. Genetic diseases, their cause and cures. Recombinant DNA and genetic engineering. Human diversity and evolution. (Lec. 3)

(3 crs.) Cross-listed as (NFS), CMB 245. This course covers the scientific principles that underpin food safety, including biological and chemical contamination, and addresses the safety of the food supply, regulatory agencies and current food safety issues. (Lec. 3)

(3 crs.) Course to educate students across disciples about modern genomic approaches that have revolutionized many aspects of human lives. (Lec. 3) (A1) (B4) (GC)

(3 crs.) Course designed to introduce students to a variety of current subjects that are hotly debated between the scientific community and the public. (Lec. 3) (A1) (B4) (GC)

(3 crs.) Chemistry of biological transformations in the cell. Chemistry of carbohydrates, fats, proteins, nucleic acids, enzymes, vitamins, and hormones integrated into a general discussion of the energy-yielding and biosynthetic reactions in the cell. (Online) Pre: CHM 124 or equivalent.

(3 crs.) Honors Section of CMB 311: Introductory Biochemistry. (Lec. 3) Pre: CHM 124 or equivalent, and 3.40 overall GPA.

(2 crs.) Laboratory exercises illustrate chemical and physical properties of biomolecules, separation techniques, enzyme catalysis, symptoms of nutritional deficiency, quantification of metabolic end-products, and drug detoxification. (Lab. 4) Pre: credit or concurrent enrollment in 311.

(2 crs.) Introduction to basic biochemistry laboratory techniques and basic methods of DNA/protein purification, quantification and analysis. (Lab. 2) Pre: credit or concurrent enrollment in CMB 311, 311H, or 210, or an equivalent course, or by permission of instructor.

(3 crs.) Cross-listed as (CMB), BIO 320. Introduction to the current topics of computational biology. Students will obtain hands-on experiences in navigating biological databases and analyzing biological data. (Lec. 3) Pre: CMB 201 or CMB 211.

(2 crs.) Investigates microbes that pose a threat to human health at the individual and population levels by implementing common laboratory-based tests aimed at identification and characterization. (Lab. 2) Pre: CMB 201 or 211.

(3 crs.) Introduction to the immune response; host resistance to infection; immunopathology; antibodies, antigens, and use of serological techniques. (Lec. 3) Pre: CMB 201 or 211.

(3 crs.) An introduction to the basic aspects of virus structure, classification, and replication as these relate to viruses as agents of infectious disease. (Lec. 3) Pre: CMB 201 or 211.

(3 crs.) Cross-list as (BIO), CMB 341. An introduction to the structure and organization of eukaryotic cells. Topics include membranes and organelles, gene expression, protein synthesis and secretion, energy utilization, the cytoskeleton, and signal transduction. (Lec. 3) Pre: one semester of biological sciences and one semester of organic chemistry.

(4 crs.) Cross-listed as (BIO), CMB 352. Introduction to basic genetic principles and concepts leading to an understanding of genes, heredity, and the nature of inherited variation. Applications and implications for animals, plants, fungi and bacteria. (Lec. 3, Rec. 1) Pre: BIO 101 and BIO 102.

(1 cr.) Cross-listed as (CMB), BIO 353. Basic principles and concepts of genetics demonstrated with microorganisms, plants, and animals. (Lab. 2) Pre: credit or concurrent enrollment in CMB/BIO 352.

(3 crs.) An introduction to laboratory biochemical techniques and methods for the purification and analysis of biological macromolecules, in particular, DNA and protein. (Lab. 6) Pre: CMB 311 and CMB 312 or 211, or by permission of instructor.

(3 crs.) The physiology, genetics, developmental, and molecular biology of microorganisms. (Lec. 3) Pre: CMB 211, credit or concurrent enrollment in CMB 311 and BIO 352, or permission of instructor.

(3 crs.) The structural, developmental, and physiological diversity of microorganisms; symbiotic relationships, molecular basis of ecology, and the role of microorganisms in the soil and water environment. (Lec. 3) Pre: CMB 211, credit or concurrent enrollment in CMB 311, or permission of instructor.

(2 crs.) Introduction to techniques and methods for advanced study of microbial genetics, physiology, molecular, and developmental biology of microorganisms. (Lab. 6) Pre: concurrent enrollment in CMB 413 or permission of instructor.

(2 crs.) Techniques and methods for the advanced study of microorganisms with emphasis on the study of representative groups of microorganisms and the application of these techniques to soil and aquatic environments. (Lab. 6) Pre: concurrent enrollment in CMB 414 or permission of instructor.

(3 crs.) Focuses on life science application of physical chemistry covering: Bioenergetics, Thermodynamics, Equilibrium, Kinetics, Quantum Theory, and Photochemistry (Lec. 3). Pre: CHM 124 or 227, MTH 103 or 111, PHY 111 or 203, or graduate standing. Not for undergraduate chemistry program credit.

(3 crs.) Introduction to the theoretical foundations underlying protein and nucleic acid structure and experimental methods for three-dimensional structure determination. (Lec. 3) Pre: CMB 311 or permission of instructor.

(3 crs.) Principles of bacterial pathogenesis with an emphasis on cellular and molecular mechanisms of diseases caused by clinically relevant bacteria. Laboratory focus on diagnostic methods (Lec. 2, Lab. 1) Pre: CMB 201 or CMB 211.

(3 crs.) Principles of bacterial pathogenesis with an emphasis on cellular and molecular mechanisms of diseases caused by clinically relevant bacteria. (Lec. 3) Pre: CMB 201 or CMB 211.

(3 crs.) Comprehensive instruction in the biology, genetics and biochemistry of cellular transformation and cancer. (Lec. 3) Pre: CMB 311 or CMB 352, or permission of instructor.

(3 crs.) Cross-listed as (BIO), CMB 437. Biochemical basis of heredity as seen through the structure and function of nucleic acids. Includes DNA replication, transcription, translation, gene regulation, and gene organization in prokaryotes and eukaryotes. Current methods emphasized. (Lec. 3) Pre: CMB 211, BIO 352, and CMB 311, or permission of instructor.

(3 crs.) Cross-listed as (CMB), BPS 450. Introduction to practical ways to analyze DNA, protein and genome datasets. Students will be introduced to computing environments and publicly available software tools for analysis. (Lec. 2, Lab. 2) Pre: CMB 311 or BIO 352 (or CMB 352) or BIO 341 or permission of instructor. Not for graduate credit.

(1 cr.) Analysis of subcellular processes, structures, and molecules using techniques including gel electrophoresis, spectrophotometry ultracentrifugation, and protein purification. Topics range from analysis of gene expression to subcellular localization of enzymatic activity. (Lab. 2) Pre: concurrent enrollment in CMB 453 or permission of instructor.

(3 crs.) Cross-listed as (CMB), BIO 452. More detailed treatment of topics introduced in the general genetics course (352) including aspects of transmission genetics, molecular genetics, cytogenetics, biotechnology, developmental genetics, and the impact of genetics on society. (Lec. 3) Pre: BIO 352.

(3 crs.) Structure, replication, and function of eukaryotic cells at subcellular level. Topics considered include cell membranes, cytoplasmic organelles and nuclei, cell division, cellular differentiation, and methods. Emphasis on recent publications. (Lec. 3) Pre: two semesters of biological sciences, CMB 311, junior standing, or permission of instructor.

(3 crs.) Addresses modern approaches to studying problems in advanced biochemistry, molecular and cell biology, including experimental design, genetics-based tools, fluorescence-based methodology, functional interactions, high-resolution microscopy and single molecule studies. (Lec. 3) Pre: CMB 311 or permission of instructor or graduate standing.

(3 crs.) A study of the primary and secondary molecular changes in human metabolic diseases. Topics include aging, alcoholism, arteriolosclerosis, diabetes, depression, and genetic diseases. (Lec. 3) Pre: CMB 311 or 581.

(3 crs.) Advanced discussions of selected topics in protein structure and function, enzyme catalysis and regulation, and case studies of proteins and enzymes in biological processes and diseases. (Lec. 3) Pre: CMB 311 or equivalent.

(3 crs.) Cross-listed as (CMB), MLS 483. Diagnosis of infectious diseases by use of microbiology, immunology, and hematologic and clinical chemical methods; organisms covered include viruses, bacteria, fungi, and parasites. (Lec. 3) Pre: CMB 201 or 211. Open only to medical laboratory science, microbiology, and cell and molecular biology majors or permission of instructor. (D1)

(1-6 crs.) Special problems in cell and molecular biology. Student required to outline a problem, carry on experimental work, and present conclusions in a report. (Independent Study) Pre: Permission of instructor. Open to majors in Cell and Molecular Biology. A maximum of 6 credits can be taken for major credit.

(1 cr.) Preparation and presentation of papers on selected subjects in cell and molecular biology. (Seminar) S/U credit.

(1-3 crs.) Teaching experience for undergraduates through participation in preparing and/or assisting in the teaching of microbiology laboratory courses.(Practicum) Pre: B+ or higher in CMB201 or CMB211, and permission of instructor. May be repeated for a maximum of 6 credits. S/U only.

(3-12 crs.) Professional field experience in biotechnology. The experience will be defined by a job description and learning contract arranged by the CMB internship coordinator, student intern, and relevant agency. (Practicum) Pre: junior or senior standing and approval by the CMB internship coordinator and department chairperson. A maximum of 12 credits can be taken as major credit. Not for graduate credit.

(3 crs.) Cross-listed as (CMB), MLS 501. Current methodology employed in the processing of clinical microbiology specimens, isolation and identification of pathogenic microorganisms, and determination of antimicrobial susceptibility. (Lec. 3) Pre: MLS 409 or CMB 432 or equivalent.

(1 cr.) Cross-listed as (BIO), CMB, AFS, AVS, PLS, NRS, LIB 508. Survey of biological literature including traditional methods of bibliographic control, contemporary information retrieval services, and the development of a personalized information system. (Sem. 1) Pre: graduate standing or permission of the instructor.

(3 crs.) Cross-listed as (CMB) BTC, MLS 510. This course is designed to teach the principles of laboratory management. The focus is to present underlying managerial concepts and then assist the learner in the successful application of this information to real-life situations. (Online) Pre: Graduate standing or department chair approval.

(3 crs.) Cross-listed as (MLS), CMB 513. Theory, application, and techniques used in clinical immunology: immunochemistry, serology, immunohematology, immunopathology. (Lec. 3) Pre: MLS 406 or CMB 533 or equivalent.

(3 crs.) Use of Chromatography, UV-vis-fluorescence-luminescence, and circular dichroism spectroscopy, calorimetry, electrophoresis, electron microscopy, mass spectrometry, and nuclear magnetic resonance to characterize biologically important macromolecules, such as proteins, DNA/RNA, carbohydrates, and lipids. (Lec. 3) Pre: credit or concurrent enrollment in CMB 581 and graduate status, or permission of instructor.

(3-4 crs.) Cross-listed as (CSC), STA, CMB 522, BPS 542. Integrates computing, statistical, and biological sciences, algorithms, and data analysis/management. Multidisciplinary student research teams. Modeling dynamic biological processes. Extra project work for 4 credits. (Lec. 3, Project 3) Pre: major in a computing, statistical, or biological science or permission of instructor.

(1-3 crs.) Advanced work arranged to suit the individual needs of the student. Lecture and/or laboratory according to the nature of the problem. (Independent Study) Pre: permission of chairperson. May be repeated for a maximum of 12 credits.

(3 crs.) Cross-listed (CMB) BES 526. This course introduces students to the principles of protein and nucleic acid structure and the experimental approaches used in structure determination. (Lec. 3) Pre: Permission of instructor.

(3 crs.) Introduction to the cellular, molecular, and genetic basis of the immune system, and the role of the immune system in immunity to infection, tumor and transplantation immunobiology, and immunopathology. (Lec. 3) Pre: CMB 201 or 211.

(3 crs.) Cross-listed as (AFS), CMB 534. Basic properties, classification, and evolution of animal viruses. Individual agents are studied in detail. (Lec. 3) Pre: CMB 432, 533, or permission of chairperson.

(3 crs.) The purpose of the course is to understand basic methods used to study DNA and proteins as it pertains to experimental approaches used in the laboratory. (Lec. 3) Pre: By permission of instructor.

(3 crs.) Cross-listed as (CMB), AVS 538. Principles of epidemiology, interrelationships of host, environment, and agent in infectious diseases. (Lec. 3)

(3 crs.) Cross-listed as (CMB), BPS 550. Students will be introduced to practical ways to analyze DNA, protein and genome datasets. Students will be introduced to computing environments and publicly available software tools for analysis. Pre: CMB 311 or BIO/CMB 352 or BIO 341 or permission of instructor.

(3 crs.) Cross-listed as (CMB), MLS 551. Description of the major components of biochemistry as it relates to the medical sciences. Major concepts include molecular genetics, regulatory biochemistry, and medically related applied biochemistry. (Lec. 3) Offered every third year.

(3 crs.) Recent research on the mechanism of mutation, genetic recombination, the genetic code, transposons, regulations, genetic engineering and regulation of DNA, RNA, and protein synthesis in microbial systems. (Lec. 3) Pre: CMB 201, BIO 352, and CMB 311.

(3 crs.) Addresses modern approaches to studying problems in advanced biochemistry, molecular and cell biology, including experimental design, genetics-based tools, fluorescence-based methodology, functional interactions, high-resolution microscopy and single molecule studies. (Lec. 3) Pre: Graduate standing or by permission of instructor.

(1 cr.) Reports of readings concerning the latest developments in techniques of molecular cloning and their applications in the study of various biological systems. (Lec. 1) Pre: CMB 552 or permission of instructor. May be repeated.

(3 crs.) Cross-listed as (ENT), CMB 571. A two-part investigation of insect-microbe associations, concentrating on the comparative pathobiology of microbial agents in the insect host and the transmission of disease organisms by the insect vectors. (Lec. 3) Pre: ENT 385 and CMB 211, or permission of instructor. In alternate years.

(4 crs.) Cross-listed as (OCG), CMB 576. Examines role of microbes in the oceans and their impact on oceanographic processes and biogeochemical cycles. Emphasis is on bacteria and their interactions with other marine organisms and the marine environment. Laboratory exercises make use of modern techniques to study metabolic rates and community structure. (Lec. 3, Lab. 3) Pre: permission of instructor.

(1 cr.) Cross-listed as (CMB), BIO 579. Current topics in genetics, including cytological, ecological, molecular, physiological, population, quantitative, and radiation genetics. (Seminar) Pre: CMB 352 and permission of instructor.

(3 crs.) First semester of a two-semester course on the principles of biochemistry. Topics include: bioenergetics, protein structure, enzymology, glycolysis, the tricarboxylic acid cycle, and oxidative phosphorylation. (Lec. 3) Pre: CHM 228 and 229.

(3 crs.) Second semester of a two-semester course on the principles of biochemistry. Topics include: photosynthesis, membranes, hormones, metabolism, the biosynthesis of DNA, RNA, and proteins. (Lec. 3) Pre: CMB 581 or permission of instructor.

(1-6 crs.) Cross-listed as (MLS), CMB 591. Intensive tutorial work, research, and readings in clinical microbiology. (Independent Study) Pre: graduate standing and permission of chairperson.

(1 cr.) Thorough study of original literature of some aspect of cell and molecular biology. Written abstracts or papers on assigned topics are discussed in weekly conferences with instructor. (Independent Study)

(3 crs.) Crosslisted as (CMB) BTC, MLS. The course provides advanced applications and laboratory skills needed for molecular diagnostic procedures conducted in biotechnology, clinical and research environments. (Online) Pre: Graduate standing or department chair approval.

(3 crs.) Cross-listed as (BPS), CMB 642. Biochemical and molecular aspects of chemically induced cell injury and chemical carcinogenesis. (Lec. 3) Pre: permission of instructor. Offered every third year.

(3 crs.) Students are required to outline a research problem, conduct necessary literature survey and experimental work, and present the observations and conclusions in a substantial written report. (Independent Study) Pre: graduate standing.

(2 crs.) Reports on assigned readings concerning latest developments in the field of cellular and humoral immunity presented and discussed by students. Research paper and critical review of a scientific paper required. (Lec. 2) Pre: CMB 533, CMB 311, or permission of instructor. May be repeated for a maximum of 4 credits. In alternate years.

(3 crs.) Study of recent research on the molecular mechanisms of pathogenesis. Students expected to participate in roundtable discussions of recent pertinent literature. (Lec. 3) Pre: CMB 432, 552, and CMB 311. In alternate years.

(3 crs.) Assigned research on an advanced level. Student required to outline problem, conduct the necessary literature and experimental work, and present observations and conclusions in a report. (Independent Study) Pre: graduate standing.

(1 cr.) Reports of research in progress or completed. (Seminar) Required of all graduate students in microbiology. S/U credit.

(1 cr.) An introduction to the health care and medical laboratory fields including specialty areas of medical laboratory science, professional organizations, credentialing, and the health care team approach. (Lec. 1)

(3 crs.) Introduction to the basic concepts and methodologies of medical laboratory science, including clinical aspects of its specialty areas: chemistry, hematology, immunology, immunohematology and microbiology. (Lec. 3) Pre: Credit or concurrent enrollment in CMB 201 or CMB 211.

(2 crs.) An introduction to pathology. The correlation among pathological processes and clinical symptoms and the course of disease is studied. (Practicum)

(2 crs.) Formation, structure, and action of antigens and antibodies. Methods of immunization. The laboratory emphasizes serological procedures in the diagnosis of disease. (Practicum)

(4 crs.) The relationship of bacteria and bacterial diseases of humans, with emphasis on the application of procedures to medical diagnosis. Fungi, viruses, the rickettsias, and human parasites are also studied. (Practicum)

(4 crs.) Continuation of MLS 409. (Practicum)

(4 crs.) The chemistry of body constituents and their relationship to diagnosis of human disease. Principles and methods of analysis are emphasized. (Practicum)

(4 crs.) Continuation of MLS 411. (Practicum)

(2 crs.) Instruction in drawing and processing blood and in ascertaining compatibility. Donor-recipient blood and tissue reactions are studied in detail. (Practicum)

(2 crs.) Continuation of MLS 413. (Practicum)

(3 crs.) Morphology of the blood and blood-forming organs and the study of abnormalities associated with disease. The dynamics and diagnostic tests of hemostasis are also discussed. (Practicum)

(3 crs.) Continuation of MLS 415. (Practicum)

(2 crs.) Professional topics in the medical laboratory sciences, including research methods, education, management, occupational health, public health, regulatory affairs, professionalism and ethics. (Practicum)

(3 crs.) Cross-listed as (CMB), MLS 483. Diagnosis of infectious diseases by use of microbiology, immunology, and hematologic and clinical chemical methods; organisms covered include viruses, bacteria, fungi, and parasites. (Lec. 3) Pre: CMB 201 or 211. Open only to medical laboratory science, microbiology, and cell and molecular biology majors or permission of instructor. (D1)

(3 crs.) Cross-listed as (CMB), MLS 501. Current methodology employed in the processing of clinical microbiology specimens, isolation and identification of pathogenic microorganisms, and determination of antimicrobial susceptibility. (Lec. 3) Pre: MLS 409 or CMB 432 or equivalent.

(3 crs.) Examines topics in clinical bacteriology, including pathogenicity and antimicrobial susceptibility, processing of clinical microbiology specimens, and the methodologies used to identify and characterize pathogenic bacteria. (Online) Pre: Graduate standing or by permission of instructor.

(3 crs.) The pathophysiologic mechanisms as they correlate to clinical chemistry data. Topics include mechanisms of pathology and analytical techniques. (Lec. 3) Pre: MLS 411 or equivalent.

(3 crs.) Supervisory management principles applicable to the clinical laboratory. Includes the processes of supervision, decision making, job performance and evaluation, communications, organizational behavior, and labor relations in the modern laboratory. (Lec. 3) Pre: MLS 400-level medical laboratory science internship or equivalent.

(3 crs.) Cross-listed as (CMB) MLS, BTC 510. This course is designed to teach the principles of laboratory management. The focus is to present underlying managerial concepts and then assist the learner in the successful application of this information to real-life situations. (Online) Pre: Graduate standing or department chair approval.

(3 crs.) Assigned research on an advanced level. Students required to outline problem, conduct the necessary research or experimental work, and present observations and conclusions in a written and oral report. (Independent Study) Pre: MLS 400-level medical laboratory science internship or equivalent.

(3 crs.) Cross-listed as (MLS), CMB 513. Theory, application, and techniques used in clinical immunology: immunochemistry, serology, immunohematology, immunopathology. (Lec. 3) Pre: MLS 406 or CMB 533 or equivalent.

(3 crs.) Special problems, advanced techniques, and methodology in hematology; laboratory approach emphasized. (Lec. 3) Pre: MLS 415 or equivalent.

(3 crs.) Immunohematology, blood banking, and transfusion medicine with emphasis on recent advances. Techniques used for tissue typing and organ transplantation. (Lec. 3) Pre: MLS 413 or equivalent.

(3 crs.) Current research and clinical methodology in clinical mycology, parasitology, mycobacteriology, epidemiology, and infectious disease serology. (Lec. 3) Pre: MLS 409 or CMB 432 or equivalent.

(3 crs.) Examines topics in clinical microbiology as a continuation of MLS 501. Explores concepts and laboratory methodologies of clinical disciplines: bacteriology, virology, parasitology, mycology, mycobacteriology, and epidemiology. (Online) Pre: MLS 501

(3 crs.) Applies laboratory methodologies to identify, characterize, and classify microbes from clinical microbiology specimens to assist in the diagnosis of infectious disease. (Practicum) Pre: MLS 501 and MLS 541

(3 crs.) A comprehensive study of pathophysiologic mechanisms as they relate to clinical chemistry. Topics include immunochemistry, automation, enzymology, pharmacology, and endocrinology. (Lec. 3) Pre: MLS 411 or equivalent.

(3 crs.) Cross-listed as (CMB), MLS 551. Description of the major components of biochemistry as it relates to the medical sciences. Major concepts include molecular genetics, regulatory biochemistry, and medically related applied biochemistry. (Lec. 3) Offered every third year.

(3 crs.) A review of cell and tissue structure, principles of microscopy, and cytological staining methods; overview of organization and management of cytology labs. (Practicum)

(3 crs.) Special projects in cytology, cytopathology, or cytotechnology. Students will investigate or review a topic and present a written and oral report. (Practicum)

(3 crs.) Cytopathology and clinical aspects of cervical dysplasia, carcinoma in situ, and invasive squamous cell carcinoma. Endometrial and endocervical carcinoma and other genital tract cancers will be considered. (Practicum)

(3 crs.) Benign and malignant cytology of the gastrointestinal, respiratory, and urinary tracts; study of exfoliative cells in urine, serious effusions, cerebrospinal fluid, and breast secretions. (Practicum)

(6 crs.) Microscopic evaluation and screening of benign cytological smears from cervical dysplasia, carcinoma in situ, and invasive malignant tumors of the female genital tract. (Practicum)

(6 crs.) Microscopic evaluation and screening of cytological smears from the gastrointestinal, urinary, respiratory, and central nervous systems and from other body fluids. (Practicum)

(3 crs.) The process through which candidate products produced using recombinant DNA technology are evaluated for safety and efficacy, including conductance of clinical trials, economic issues, and regulatory affairs. (Lec. 3/Online) Pre: graduate standing and permission of chairperson.

(3 crs.) The process through which candidate products produced using recombinant DNA technology are evaluated for safety and efficacy, including conductance of clinical trials, economic issues, and regulatory affairs. (Lec. 3/Online) Pre: graduate standing and permission of chairperson.

(1-6 crs.) Intensive tutorial work, research, and readings in clinical chemistry. (Independent Study) Pre: graduate standing and permission of chairperson.

(1-6 crs.) Cross-listed as (MLS), CMB 591. Intensive tutorial work, research, and readings in clinical microbiology. (Independent Study) Pre: graduate standing and permission of chairperson.

(1-6 crs.) Intensive tutorial work, research, and readings in immunohematology. (Independent Study) Pre: graduate standing and permission of chairperson.

(1-3 crs.) Intensive tutorial work, research, and readings in biotechnology. (Independent Study) Pre: graduate standing and permission of chairperson.

(3 crs.) Crosslisted as (CMB) BTC, MLS. The course provides advanced applications and laboratory skills needed for molecular diagnostic procedures conducted in biotechnology, clinical and research environments. (Online) Pre: Graduate standing or department chair approval.