Neil Greene

  • Clinical Associate Professor; Director, Medical Laboratory Science Program
  • Phone: 401.874.2315
  • Email: neil_greene@uri.edu
  • Office Location: CBLS, Rm 369

Research

Bacterial pathogenesis, antibiotic resistance, molecular genetics, clinical microbiology, science education

Education

  • Postdoctoral Research Fellow, Harvard Medical School, 2015-2017
  • Ph.D., Molecular Microbiology, Tufts University Graduate School of Biomedical Sciences, 2015
  • B.S., Microbiology, University of Rhode Island, 2010

Selected Publications

Sardis MF, Bohrhunter JL, Greene NG, Bernhardt TG. (2021) The LpoA activator is required to stimulate the peptidoglycan polymerase activity of its cognate cell wall synthase PBP1a. Proc Natl Acad Sci U S A. 118(35): e2108894118.

Greene NG, Fumeaux CF, Bernhardt TG. (2018) Conserved mechanism of cell-wall synthase regulation revealed by the identification of a new PBP activator in Pseudomonas aeruginosa. Proc Natl Acad Sci U S A. 115(12): 3150-3155.

Greene NG, Narciso AR, Filipe SR, Camilli A. (2015) Peptidoglycan branched stem peptides contribute to Streptococcus pneumoniae virulence by controlling pneumolysin release. PLoS Pathog. 11(6): e1004996.

Karmakar M, Katsnelson M, Malak HA, Greene NG, Howell SJ, Hise AG, Camilli A, Kadioglu A, Dubyak GR, Pearlman E. (2015) Neutrophil IL-1β processing induced by pneumolysin is mediated by the NLRP3/ASC inflammasome and caspase-1 activation and is dependent on K+ efflux. J Immunol. 194(4): 1763-1775.

Price KE, Greene NG, Camilli A. (2012) Export requirements of pneumolysin in Streptococcus pneumoniae. J Bacteriol. 194(14): 3651-60.

Silverman JL, Greene NG, King DS, Heldwein EE. (2012) Membrane requirement for folding of the Herpes simplex virus 1 gB cytodomain suggests a unique mechanism of fusion regulation. J Virol. 86(15): 8171-84.