Dr. Albert P. Kausch

Biographical Sketch

Dr.Albert Kauschis currently a Professor at theUniversityofRhode Islandin the Department of Cell and, Molecular Biology with a research focus on molecular improvement and gene discovery in grasses and cereal crops.  His major educational interests have concentrated on the development of curricula for teaching biotechnology. He conducted his undergraduate work at the State University of New York, College atOswegowith a Bachelors Degree in Biological Science with a focus on botany, plant science and chemistry. After completing a Master’s and Ph.D. in Molecular, Cellular and Developmental Biology atIowaStateUniversity, Dr. Kausch accepted an NIH Postdoctoral Fellowship at The Rockefeller University inNew Yorkworking in the laboratory of  Dr. Tony Cashmore on early gene transfer methods to plants.  He also did postdoctoral work in collaboration with Dr. Marc Van Montague’s laboratory inGhent,Belgium, where they conducted seminal research on chloroplast protein targeting in transgenic plants that resulted in several landmark publications and four international patents.  This technology is now utilized in all commercial varieties of Round-up Ready plants, which includes transgenic maize and over eighty percent of last year’s US soybean crop.

He then joined the plant molecular biology group with DeKalb Genetics Corp., at that time in association with Pfizer Inc., to work on gene transfer technologies for genetic engineering of corn.  During that time, Dr. Kausch worked with a team that developed the first genetically modified corn plants.  He has directed diverse research areas in agricultural biotechnology of corn, rice, alfalfa and other crop plants including: herbicide and insect resistance, drought tolerance and yield stability, nutritional improvement, gene regulation, transformation technology development, site specific recombination using FLP/FRT and Cre/lox systems (and a range of other projects). Albert Kauschhas over eighteen years experience in commercial agricultural biotechnology. His broad industry experience includes: management, research, intellectual property rights and patents, licensing, regulatory affairs, marketing and public perception. He has been involved with three biotechnology start-up companies, and maintains several active research collaborations world-wide on genetic modification of crop plants.

Dr. Kausch has extensive academic experience and has taught at Mount Holyoke College, The University of New Hampshire, The University of Connecticut, Connecticut College, and the University of Rhode Island, where he currently teaches a new general undergraduate course titled “The Way We Work With Life: Issues in Biotechnology” and a two semester project-based training program titled “Modern Techniques in Plant Biotechnology”.  The course titled “The Way We Work With Life: Issues in Biotechnology (BCH 190) is now a General Education course at URI which has been funded by grants from Pfizer and Amgen Foundations to be filmed and is now shown on public access television throughout Rhode Island.” This course is also now being developed as the first on-line and distance learning course through URI. The second experimental course, “Modern Techniques in Plant Biotechnology” is unique in theUnited States and provides each student with experimental genetic constructs to introduce and evaluate in transgenic grasses and rice.

Dr. Kausch has been involved with the development of several agricultural biotechnology start-up companies and an educational nonprofit organization that are related to his work. For example, during the past several years Dr. Kausch has developed a new variety of garlic as a new vegetable called ‘Baby Green Garlic’ which has launched a new company called Ophios and has been successful in the marketplace. This variety was selected from wild germplasm and is now being developed as a new vegetable. This project has initiated research into the genetics of the biochemical pathways of thiosulfinates, which are the flavor and medicinal compounds in garlic. He was also involved with a agricultural biotechnology start-up company called HybriGene Inc. that developed genetically modified turfgrasses for trait improvement. One of the major research areas of focus in HybriGene was to develop gene confinement methods for perennial plants and they have successfully completed development of pollen sterility technology and have filed patents on additional technologies. This technology has been extended to other grasses, including switchgrass.

Dr. Kausch’s current research is on the genetic improvement of switchgrass for biomass used for biofuels. Dr. Kausch recently (FY08) received a $1.4 million award from the Department of Energy to fund basic research on genetics and trait improvement in swithgrass for biofuels.  This award was renewed, FY09 and FY10 each for an additional $1.5 million, and in FY11- FY13 for $1.7 million each year. He is a co-founder of a new company, called Plant Advancements which will help commercialize the results of basic research into practicality.  Plant Advancements, LLC, in association with Ernst Conservation Seeds Inc., is a renewable bioenergy company with a focus on the development and primary production of biomass for the growing bioenergy industries and hybrid plant systems for grain crops. Recognizing the need for dedicated energy crop development, Plant Advancements research in collaboration with theUniversityofRhode IslandandYaleUniversity, is developing new technologies as well as new elite and improved varieties of switchgrass and other dedicated energy crops and products used for bioenergy.  The broad mission of the company is use conventional breeding, genomics, advanced breeding, and biotechnology to produce new varieties that will provide sustainable solutions for bioenergy industries. Plant Advancements has designed proprietary gene confinement hybrid systems as operating platforms that will be required for regulatory and environmental stewards for the deployment of genetic modification for enhancing biofuel production and encourages collaborations.

Dr. Kausch has helped to form The Bioenergy Consortium to accomplish these goals. This organization includesYaleUniversity, theUniversityofRhode Island, theUniversityofConnecticut, and Ernst Conservation Seeds, Inc.  Ernst Conservation Seeds Inc., who specializes in the production of native and naturalized seeds and plant material of Eastern North American ecotypes, is currently the largest producer of commercial seed for switchgrass and related bioenergy grasses in the world and brings a special expertise to this project. Plant Advancements, with Ernst, is the commercializing arm of the Bioenergy Consortium, and is situated to be the largest supplier of switchgrass as raw materials for the bioenergy industry.

Engineering Environmental Stewardship and Bioenergy Traits One obstacle that arises regarding transgenic improvement of perennials, such as switchgrass, is the propensity of these plants to be open pollinated with the undesirable capacity of outcrossing to wild relatives species. Therefore, a stringent transgene confinement technology is a requisite platform for the future commercialization of perennial transgenic plants to be used for bioenergy. In addition, when plants flower, valuable carbon resources are reallocated to the inflorescences at the expense of vegetative biomass. Engineered total plant sterility will eliminate the possibility of transgene escape with the desirable result of increased biomass yield. The overarching goal of this project is the development of commercial switchgrass hybrid varieties engineered for enhanced, low-cost conversion of cellulosic biomass to fuel with total transgene confinement. These enhanced hybrids will express a suite of trait genes necessary for incorporation into existing and planned cellulosic biofuel-producing commercial programs.

As Director of the Plant Biotechnology Laboratory at the Universityof Rhode Islandsince 2004 Dr. Kausch has formed many collaborations with molecular biologists in industry, academics and government. The Plant Biotechnology Laboratory is fully equipped for plant transgenic technology applications and molecular biology, and is available to provide the necessary laboratory facilities required for the program. The PBL comprises more than 5700 sq ft of research and teaching laboratory space that is equipped for plant transgenics and molecular biology. This space includes a media prep lab, eight tissue culture labs, a DNAprep lab, a molecular biology lab, a walk-in plant growth chamber, and a plant growth facility with incubators. Standard equipment in the plant transgenics lab infrastructure includes: 18 laminar flow hoods that provide sterile bench top space for tissue culture manipulations, media preparation equipment, autoclaves, water purification systems, gene transfers capabilities, including a gene gun for biolistics delivery (PDS1000/He Particle Delivery System, Bio-Rad), Si whisker technology, electroporation devices, incubators, growth chambers, and standard equipment required for Agrobacterium-mediated gene transfer in plants.

Dr. Kausch teaches a general undergraduate course for majors and non-majors titled Issues in Biotechnology.  This has been a wildly popular course at the Universityof Rhode Islandover the past ten years. In order to develop an effort to increase awareness and outreach concerning controversies about biotechnology, Dr. Kausch has founded a new non-profit organization, called lifeedu.org to create and produce educational materials, workshops, and programs on all of the various fields in biotechnology.  lifeedu has developed DVDs and YouTube lecture series and a massive open on-line course (MOOC) as educational teaching tools onDNA, Genetics and Biotechnology for General Undergraduate, K-12 teachers and the General Public.  He has authored or co-authored numerous research papers, book chapters and review articles, is the editor on 42DVDs on biotechnology education, and is an inventor or co-inventor on over 38U. S. and world-wide patents in various stages of issuance in fields of molecular and agricultural biotechnology.

Dr. Albert Kausch currently resides inStonington,Connecticut.

Personal History and Professional Experience

Educational Background

  • Bachelor’s degree in Biological Sciences, 1978.State UniversityNew York,Oswego
  • M.S. in the Molecular, Cellular, and Developmental Biology Program and The Department of Botany, 1980. IowaStateUniversity,Ames,IA
  • Ph.D. in the Molecular, Cellular, and Developmental Biology Program and The Department of Botany,
  • 1983.IowaStateUniversity,Ames,IA.
  • Postdoctoral 1984-87.  The Rockefeller University,New York City,NY,

List of Academic and Industry Positions since Final Degree

  • National Institute of Health Postdoctoral Fellow: Department of Cell Biology, TheRockefellerUniversity,New York City,NY, 1984‑1987. In collaboration with Dr. Marc Van Montague’s laboratory; University ofGhent,Ghent,Belgiumand theUniversityofNew Hampshire.
  • Visiting Professor: One yr teaching appointment. Department of Biological Sciences,MountHolyokeCollege,South Hadley,MA, 1987‑1988.
  • Research Scientist: Pfizer, Inc/ DeKalb Genetics Corp. Plant Molecular Biology, 1988‑1990.
  • Senior Research Scientist: DeKalb Plant Genetics, Maize Transformation Discovery Research, 1991-1993.
  • Senior Project Leader: DeKalb Plant Genetics, Transgenics Technology Development 1993-1998
  • Associate Professor Dept. of Plant ScienceUniversityofConnecticut(1997-1998)
  • Vice President/Director of Research, HybriGene, Inc. West Kingston, RI & Visiting Professor, Dept. Plant Science, & Dept. Cellular and Molecular Biology, University of Rhode Island, South Kingston, RI. President and Founder of life edu.org  (1999-2004)
  • Professor: Dept. Cell and Molecular Biology, Universityof Rhode Island, South Kingston, RI. (2004-present)

 

Concurrent  Academic Appointments*

* Throughout full-time employment in various industry positions, Dr. Kausch maintained several active academic commitments. He has served as a Visiting Professor at theUniversityofNew Hampshire, and also atConnecticutCollege, teaching various courses, and serving as an Undergraduate Research Independent Studies Advisor. He developed an undergraduate internship program at DeKalb Genetics Corporation.  He has also taught and served on several graduate thesis committees at The University of Rhode Island. Dr.Albert Kauschis currently a Professor at theUniversityofRhode Islandin the Department of Cell and Molecular Biology.

  •  Visiting Professor:University ofNew Hampshire, Department of Botany,Durham,NH, 1987
  • Visiting Professor:ConnecticutCollege, Department of Botany,New London,CT, 1992. (taught Plant Structure and Function Bot. 226) Adjunct Professor/Student Internship Advisor:ConnecticutCollege,  Department of Botany , New London, CT, 1990-present (advisor for 12 Independent studies students)
  • Visiting Professor:ConnecticutCollege, Department of Botany,New London,CT, 1995, 1997 (taught Botany 491: Plant Biotechnology)
  • Adjunct Professor/Ph.D. Advisor:UniversityofRhode Island, Department of Botany, South Kingston R.I., 1991-93 (Graduate Advisor and Thesis Committees)
  • Adjunct Professor:UniversityofRhode Island, Department of Biochemistry, Microbiology, and Molecular Genetics, South Kingston R.I., 1991-2004 (Graduate Thesis Committees)
  • Professor: Universityof Rhode Island, Department of Plant Sciences & Department of Cell and Molecular Biology, South KingstonR.I., Present
  •   NIH Post‑doctoral Fellowship Research

NIH Postdoctoral Fellow: Laboratory of Dr. Anthony R. Cashmore, 1983-86.  Dept. of Cell Biology,RockefellerUniversity,1230 York Avenue,New York City,NY. In collaboration with Dr. Marc Van Montague’s laboratory;University ofGent,Gent,Belgium.

Early work on Agrobacterium‑mediated plant cell transformation and transgenic plant regeneration; Promoter dissection and analysis, Light regulated gene expression of nuclear encoded chloroplast proteins Nature318:579‑582.; Organelle isolation and physiology, protein targeting; Post‑translational import of polypeptides into chloroplasts; Targeting of foreign proteins to organelles by chimeric genes encoding transit peptides (Nature 313:358‑363). This work resulted in four majorUS patents on using the transit peptide for directing foreign proteins to chloroplasts in genetically engineered plants (US PTO Number 5,728,925,  Number 5,717,084, Number 6,063,601 and Number 6,130366)

Teaching Experience

Iowa State University: Graduate Teaching Assistant (1978-1983): Courses: General Biology Laboratory. General Botany. Morphology of Vascular Plants. Laboratory of Plant Cell and Tissue Culture. Plant Anatomy. Electron Microscopy I and II. Scanning Electron Microscopy and X‑ray Microanalysis.  Transmission Electron Microscopy. Plant Cell and Tissue Culture.

Mount Holyoke College: Assistant Professor  (1987-1988).

  • Courses: Molecular Biology of the Cell; 1987, Laboratory for Molecular/Cell Biology; 1987.
  • Plant Physiology. 1987.  Electron Microscopy for Biology; 1988.
  • Undergraduate Thesis Research Advisor: Senior Honors Thesis student: Cynthia J. Grondin; 1988. Tissue specific localization of bromelin in Ananus comosus. Research supported by a grant from Del Monte Corp.

Connecticut College: Visiting and Adjunct Professor (1992-present)

  • Courses: Plant Structure and Growth, 1992. Laboratory for Plant Structure and Growth, 1992 Developmental Plant Biology, 1994 Special Topics in Botany: Plant Biotechnology, 1995 Current Topics in Botany: Plant Biotechnology, 1997 Issues in Biotechnology, 2002 Pfizer Corporation Sponsorship
  • Undergraduate Research Independent Studies Advisor,ConnecticutCollege(1992-1997)
  • Dr. Kausch has served as an undergraduate research advisor for nineteen students fromConnecticutCollege.  Four have been co-authors on reviewed journal publications, and seven are currently working in life sciences or in graduate school.

University of Connecticut: Associate Professor (1997-1998)

  • Courses: Modern Techniques in Plant Biotechnology, Laboratory and Lecture. 1998.

University of Rhode Island: Professor (present)

  • URI Courses:
    • BMMG  Plant Transgenics (funded by DeKalb Genetics Corporation).  Spring 1997
    • Special Topics in Plant Science: Plant Biotechnology and Agriculture. Spring 1999
    • PLS 491/591 Gene Transfer to Plants. Fall 1999.
    • PLS 492/592  Molecular analysis of transgenic plants. Spring 2000.
    • AFS190, NRS 190, PLS 190, MIC 190 and BCH 190 Issues in Biotechnology. Fall 2001-present
    • BCH 491/492 Research in Plant Molecular Genetics
    • AFS190, NRS 190, PLS 190, MIC 190 and BCH 190 OnLine Issues in Biotechnology. 2011-present.

Curriculum Improvement: New Courses:

  • AFS 190, PLS 190, MIC 190 and BCH 190 Issues in Biotechnology. Fall 1999/ Fall 2000/Spring 2001/ Spring 2003, Fall 2004, Spring 2005, Summer Session 2005, Fall 2005 Development of on-line classes and  distance learning. This is now a General Education course at URI
  • Modern Techniques in Genetic Engineering  PLS 481/482 Fall 2002/Spring 2003, Fall 2004/2005
  • URI Internship program PLS 491/492, F/S 2001, F/S 2002,  F/S 2003, F/S 2004, F/S 2005-present

URI Graduate Ph.D. Thesis committees

Dr. Kausch has served on seven Ph. D committees, and three MS committees for the University of Rhode Island and played an active role in graduate and undergraduate student research ( names, dates and thesis titles available on request) Current-John Longo University of Rhode Island, Department of cell and Molecular Biology, South Kingston RI, 2003-2006 Transposon Mutagenesis in rice  Joel Hague University of Rhode Island, Department of cell and Molecular Biology, South Kingston RI, 2003-2004 developmental analysis of the maize pollen specific promoter. Adam Deresienski: Methods for producing wide crosses in Panicum species; John Ventura: Analysis of ts1 mutations in rice

Recent Grants; Recent, Current and Pending Support (1999-2013 only)*

Pending

  • USDA/DOE Grants Program. Genetic Improvement of Switchgrass for Bioenergy Traits  Albert Kausch        and Stephen Dellaporta  $1,463,784  09/01/13-08/31/16
  • NSF Plant Genome Program. Transforming Cereal Genomics: Tooling Up For Empowered Cereal Crop Albert Kausch and Stephen Dellaporta  $1,500,000 9/1/2013-8/31/2017
  • USDA/SBIR Grants Program. Grant titled Development of Green Garlic as A New Vegetable Crop for the US Consumer Albert Kausch  $100,000  8/31/13
  • USDA/SBIR Grants Program Grant titled Commercial Production of Green Garlic as A New Specialty Crop Albert Kausch  $100,000  8/31/13
  •  USDA/SBIR Grants Program Grant titled Hybrid Systems for Gene Confinement and Breeding of Perennial Plants Used for Biofuels.  Albert Kausch  $100,000  8/31/13

 Current 

  • USDA/SBIR Grants Program Grant titled Hybrid Systems for Gene Confinement and Breeding of Perennial Plants Used for Biofuels.  Thomas Hodges and Albert Kausch  $100,000  5/1/12-8/31/13 
  • Department of Energy Grant titled-“Genetic Improvement of Switchgrass, Gene Confinement Strategic Development. (Award # DE-FG-36-08GO88070)  Albert Kausch and Richard Rhodes III $2,903,250 start 12/30/11 – 11/30/13Universityof Rhode Island
  • NSF BREAD Grant Program with HarvestPlus Grant titled- Transgenic Products to Increase Carotenoid and Iron Levels in African Maize Stephen Dellaporta, Albert Kausch, Joseph Tome, and Cesar Martinez  11/01/09 – 06/30/12 No Cost Extension 03/01/14Yale University, University of Rhode Island, CIAT
  • HarvestPlus Grant titled- Transgenic Products to Increase Carotenoid Levels in African Maize Stephen Dellaporta, John Mottinger, Albert Kausch, Joseph Tome, and Cesar Martinez  HarvestPlus $ 161,939 11/01/09 – 06/30/12 Yale University, University of Rhode Island, CIAT

Recent Funded Grants

Department of Energy Grant titled-“Genetic Improvement of Switchgrass, Gene Confinement Strategic Development. (Award # DE-FG-36-08GO88070)  Albert Kausch and Richard Rhodes III $ 1,500,822 start12/30/10-12/01/11Current University of Rhode Island

Department of Energy Grant Titled-“Genetic Improvement of Switchgrass, Gene Confinement Strategic Development. (Award # DE-FG-36-08GO88070)  Albert Kausch and Richard Rhodes III $ 1,500,243 start12/30/09-12/01/10Universityof Rhode Island

Department of Energy Grant Titled-“Genetic Improvement of Switchgrass, Gene Confinement Strategic Development. (Award # DE-FG-36-08GO88070)  Albert Kausch and Richard Rhodes III $ 1,500,243 start 12/30/08 – 12/01/09Universityof Rhode Island 

USDA-Biotechnology Risk Assessment Grant Titled- “Development of controlled total vegetative growth for prevention of transgene escape from genetically modified turfgrass.” 2006  H. Luo, A.Kausch, J. Chandlee, M. Oliver. $399,982.00 start01/01/06- end01/01/09

USDA-CSREES Titled-“Educating the Educators: With Further Advances in Agricultural Biotechnology Education Enrichment for the K-12 School Teachers” 2005 Jeff Adelberg; Richard Wallace; Carol M. Stiff;Albert Kausch,  Bruce W Wood. $256,427.00 start10/01/05- end05/01/07

NRICGP-USDA- Equipment Grant Program. Titled- “Infrastructure for Plant Biotechnology at URI.” 2005 Albert Kausch,. and Hong Luo$33,868 start 09/01/05- end 09/01/06

USDA Special Programs Grant. Titled- “Environmental Biotechnology at URI.” J. Seemann,Paul Cohen, T. Bradley, M. Gomez-Chiarri, A. Kausch, T. Mather, and D. Nelson. 2005 $572,604 start09/01/05- end09/14/05

Corporate Sponsorships from Scotts Co., Delta Pine and Land Co. John Deere Co., Monsanto Co., EPIC Wisconsin Inc., HybriGene Inc., Bayer Crop Science, and Tee-Green Corp.  Titled-“Gene Confinement for Genetically Modified Grasses.” A Symposium co-sponsored byYaleUniversity’s Interdisciplinary Bioethics Projects, Yale University New Haven, CT and lifeedu.org  $40,000. start02/01/05- end05/14/05

Pfizer Foundation. Titled-“Production of a Distance Learning Course and Educational Materials on DNA, Genomics, and Current Topics in Biotechnology.”Albert Kauschand lifeedu $ 15,000.00 (active) start06/01/05- end05/01/06

NRICGP-USDA-Seed Grant  Program. Titled- “Infrastructure for Plant Biotechnology at URI.” 2004 Joel Chandlee,  Hong Luoand Albert Kausch,. $49,612.00  start 09/01/04- end 05/01/05

Rhode Island School-to-Career Strategic Focus & Core Elements of INVESTMENT 2004 Region IISouthern Rhode IslandCollaborative. Gerard BertrandandAlbert Kausch  $25,000.00 start06/01/04- end08/28/04

SlaterCenterfor Marine and Environmental Biotechnology Program Phase I. Titled-“Ophios: An agricultural biotechnology company that specializes in production and development of hardneck garlic varieties.” 2004. Albert KauschandPeter Sellew$80,000.00 start02/01/04- end05/01/06

AMGEN FoundationRhode Island. Titled-“Production of a Distance Learning Course and Auto-tutorial Educational Materials on DNA, Genetics, and Current Topics in Biotechnology.”Albert Kauschand lifeedu $ 98,000.00 start08/30/04- end05/14/05

Pfizer Foundation. Titled-“Production of a Distance Learning Course and Auto-tutorial Educational Materials on DNA, Genetics, and Current Topics in Biotechnology.”Albert Kauschand lifeedu $ 50,000.00

USDA-SBIR Program. Phase I Titled ’ Use of site specific recombination  for hybrid rice production.” 2003

Albert Kausch, andHong Luo. $75,000.00 

NRICGP-USDA-Seed Grant  Program. Titled- “Stable expression of yeast FLP site specific recombinase in rice.” 2001 Albert Kausch, Joel Chandlee, and Hong Luo. $74,945.00

Pfizer Foundation. Titled-“Initiation of a new nonprofit organization for the production and creation of educational materials on DNA, Genetics and Biotechnology: Lifeedu.orgAlbert Kauschand lifeedu $ 50,000.00 

Rose Environmental Biotechnology Undergraduate Student Internship Program. Titled- “ Undergraduate biotechnology laboratory experience.” 2003.Albert KauschandBill Rose.  $41,000.00

SlaterCenterfor Marine and Environmental Biotechnology Program Phase II. Titled-“Genetic modification for Turfgrass Improvement.” 2003. Albert KauschandBill Rose  $100,000.00

Rose Environmental Biotechnology Undergraduate Student Internship Program. Titled- “ Undergraduate biotechnology laboratory experience.” 2002.Albert KauschandBill Rose.  $43,000.00

Rose Environmental Biotechnology Undergraduate Student Internship Program. Titled- “ Undergraduate biotechnology laboratory experience.” 2001.Albert KauschandBill Rose.  $13,000.00

SlaterCenterfor Environmental Biotechnology Program. Phase I Titled-“Genetic modification for Turfgrass Improvement.” 2000. Albert Kausch  $87,000.00

AgriBiotech Inc. Corporate Graduate Student Fellowship Award. Titled-“Genetic Modification of Turfgrass.” 2000Albert Kausch, $13,700.00 Funding awarded to Chhandak Basu as a Ph.D. Grant.

USDA-Higher Education Challenge Grants Program. Titled-“Providing Undergraduate Experiential Learning Opportunities in Plant Biotechnology.”  Joel Chandlee, Albert Kausch and W. M. Sullivan  1999 $88,000.00

NRICGP-USDA-Equipment Grant .UniversityofRhode Island. Titled-“Equipment request to strengthen infrastructure for plant biology research at URI”Joel Chandleeand Albert Kausch 1999. $24,610.00

The Champlin Foundations.UniversityofRhode Island. Titled- “The Environmental Biotechnology Initiative: Establishment of a Multi-User Facility for Transgenics Training and Research.”Terry BradleyandAlbert Kausch. 1999. $149,409.00

Total funding for the 1999-2013 period -$18,580,157

* First author listed is the Principle Investigator

Agricultural Biotechnology Experience in Private Industry

                Brief Descriptions of Activities and Accomplishments

  Pfizer, Inc. Research Scientist (1988-1992) Head of Plant Cell Culture/Corn Transformation 

Research team developed first genetically modified corn plants.  Directed project to develop appropriate cell  culture, gene transfer and selection system for transformation of corn. (see US patent Numbers 5,489,520 and 5,550,318). Managed a team of nine research and technical assistants.  Developed a project on magnetic separation of bio-macromolecules, cells and organelles (seeUSpatent No. 5,508,164). 

DeKalb Genetics Corporation Senior Research Scientist (1992-1993) Head of Yield Stability

Managed team of nine full time employees. Yield Stability; Drought Tolerance; and Transformation Technology Development in Corn, Developed project on drought tolerant maize by genetic engineering approaches with a research group of five research assistants (see US patent 5,780,709;1998).

 DeKalb Genetics Corporation Senior Project Scientist (1993-1994) Head of Transformation Technology Development 

Directed Transformation Technology Development in maize at DeKalb Genetics.  Focus: Transformation  development research in maize (see US patents, 6,281,411; 2001, 5,874,265; 1999 and 5,489,520; 1996)

Established a program for Undergraduate Independent studies students and student internships betweenDeKalb Genetics,ConnecticutCollege and theUniversityofRhode Island

DeKalb Genetics Corporation Senior Project Leader (1994-1997)   Transformation Technology Development

Gene targeting by site directed integration via Cre/Lox system ; promoter and gene expression studies; gene silencing Development of a promoter evaluation research project to study product gene expression in transgenic maize.  Evaluation of CaMV 35S, aldolase, rice actin 1, and maize adh1.

Developed educational materials and tours of the facility regarding biotechnology and gene transfer to corn.

Biotechnology Start-up company employment/involvement 

Ig. Tech, Inc. Co-Founder & Consultant 1997 Co-Founding member, as plant molecular biologist, of an effort to produce antibodies in plants for animal health care products. Raised over $2.8 million in financing.  Sold company to multi-nationals.

HybriGene Inc.  1998-2004 Vice President/Director of Research Gene Discovery and Genetic Improvement in Grasses and Cereal Crops HybriGene Inc. is an agricultural biotechnology company focusing on genetic improvement in turfgrasses and cereal crops. Responsibilities included direction and management of the laboratory in West Kingston RI, licensing arrangements, patent preparation and intellectual property; grant (SBIR) and business plan writing, etc. HybriGene has raised over $ 6.2 million in financing.  Designed transgenic laboratory for transformation of turf crops and exotic grasses and maintain  direction of the Rose student internship program or undergraduates at URI.  Responsible for hiring scientific all staff  for molecular biology and plant transformation laboratory in West Kingston RI.  Trait development and trait gene acquisition for crop improvement in alfalfa, forage, and cool-season turf species.  Management of fifteen full time employees.  Development of university and industry collaborations in the United States and Eastern Europe. Licensing of genes and technology. Development of University/Industry interactions and a collaborative internship.

Ophios LLC 2004-present Co-Founder, Chief Scientific Officer and Director of Research:  An Agri-Food Production Company specializing in Fresh Green Garlic. Established and invented a new vegetable called Fresh Green Garlic, patents issued and pending.

Plant Advancements LLC 2009-present Co-Founder, in association with Ernst Conservation Seeds Inc., Plant Advancements, LLC is a renewable bioenergy company with a focus on the development and primary production of biomass for the growing bioenergy industries. The broad mission of the company is use conventional breeding, genomics, advanced breeding, and biotechnology to produce new varieties that will provide sustainable solutions for bioenergy industries. Plant Advancements has designed proprietary gene confinement hybrid systems as operating platforms that will be required for regulatory and environmental stewards for the deployment of genetic modification for enhancing biofuel production and encourages collaborations. In addition, Plant Advancements has formed The Bioenergy Consortium to accomplish these goals. This organization includesYaleUniversity, theUniversity ofRhode Island, theUniversity ofConnecticut, and Ernst Conservation Seeds, Inc.

H.  Selected Major Scientific Achievements and Contributions in Biotechnology 

Demonstrated targeting of foreign proteins in transgenic plants. (Postdoctoral ) Four  major worldwide patents. This technology has been used in all Round-up Ready crops. Co-inventor on four major world wide patents for the use of the transit peptide for targeting any foreign protein to chloroplasts in transgenic plants USA patent numbers 5,717,084;  5,728,925, 6,063,601 , and 6130366).  This technology is currently applied in all Round-up Ready and many Bt driven insect resistant plants ( a total of over 140 million acres in the US, including cotton, wheat, rice, corn, and soybeans)These patents derive from work conducted during Dr. Kausch’s postdoctoral at the Rockefeller University in collaboration with Plant Genetic Systems, Inc. and Marc Van Montague’s laboratory in Gent Belgium. 

Co-inventor on several major patents for corn transformation (for example, see USpatent numbers 5,489,520 and 5,550,318): these patents attracted world-wide attention and had a significant affect on DeKalb stock. This work focused on development of corn transformation by microprojectile bombardment and the production of herbicide resistant plants.  Additional patents in transformation related areas resulted in a related family of IP. 

Designed, organized, and coordinated an effort focused on several molecular approaches to Yield Stability (for example, see USpatent number 5,780,709) for traits including drought tolerance, chilling and freeze tolerance, salt tolerance and others in corn. Contributions as a co-inventor resulted in filed patent applications. Collaborated on projects related to enhanced Grain Quality. 

Conceived, and to developed early technology for biological magnetic separation technology.  This work resulted in two issued patents. Procedures for large scale DNA insert isolation by triple helix magnetic affinity capture (Nucleic Acids Res. 1995, 19:26) resulted in a commercially produced kit marketed by Boerhinger Mannhiem. Inventor of technology and methods for immuno-isolation of biological materials including chromosomes and organelles (see references and attached patent, US patent No. 5,508,164)

Designed five (5) Plant Transgenics Laboratory Facilities Genetic transformation technology development in many species (maize, rice, tobacco, Arabidopsis, pea, rhododendron, alfalfa, and many turfgrass species) by many techniques (Agrobacterium-mediated gene transfer, biolistics, protoplast electroporation, silicon carbide-mediated directDNA uptake, and many others). Development of novel transformation methods for plants.

Developed Green Garlic as a new vegetable.  Kausch, A.P., and P. Sellew 2011 Green Garlic and Methods of Production. US Patent Number 7,937,889, Issued May 10 2011.

Established a new breeding technology called in-situ embryo rescue for recovery of wide genetic crosses in switchgrass and other biofuels crops.

Developed a Research Group addressing the development of a commercializeable approach to artificial photosynthesis  for hydrogen production.

Biotechnology industry start-up companies and non-profit interests

Ig.Tech, Inc. (SOLD-2001)

Development of antibodies in transgenic plants for veterinary markets

“The New Generation of Products for Animal Health”

Co-Founders:  Manuel Campos, Osvaldo Lopez , Serge Martinod, andAlbert Kausch

Ig.Tech is a biotechnology start-up company specializing in the development of new therapies for disease prevention and treatment in animal health applications.  The primary focus of the company is to identify and develop antibodies with specificities and functions that will be introduced as innovative veterinary products in national and international markets.  The founders are experienced immunologists, veterinarians and scientists in the areas of animal health biologicals and plant molecular biology.  Their academic and industrial background combined with their individual networks, project management, and business development experience is specially suited to create and develop a portfolio of innovative antibody-based products.

Ig.Tech established a large 3-year $2.9 million collaboration with a major Life Sciences company in the development of plant-derived antibody products for animal health markets worldwide.  The collaboration provided funding for Ig.Tech’s research related to this project. Together, the companies  demonstrated that antibodies are a feasible and profitable alternative to conventional and traditional animal health products. This collaboration was bought out by the investors in 2002

 

 HybriGene, Inc.

Genetic Modification for Turfgrass and Cereal Improvement

Dr.Albert Kausch, former Vice President and Director of Research 

HybriGene is a stage II agricultural biotechnology company whose primary focus is the development of new products for the turfgrass seed industry and hybrid cereal crop plants through genetic modification. The company was initially established in 1999 by Dr. Thomas K. Hodges, Distinguished Professor in the Department of Botany and Plant Pathology, Purdue University, and Mr. Bill L. Rose, President of Turf Seed, Inc.  Dr. Hodges led a research team that developed several patentable technologies that are currently quite valuable to the agricultural biotechnology industry. HybriGene is headquartered in Oregonnear Hubbard.  The main company laboratory, currently located in West Kingston, Rhode Island, is a fully functional plant transgenics and plant molecular biology facility capable of performing all of the technical aspects necessary to commercialize new turf varieties with improved traits. The primary focus of the HybriGene laboratory is to produce new varieties of grasses and cereals with commercial potential.  Hybrigene has received over $ 4.5 million in private and federal (SBIR) financing.  With HybriGene, Inc. in collaboration with the Universityof Rhode Island, Dr. Kausch has developed a paid, or for-credit, student internship program in plant biotechnology, and a two semester project-based training program titled “ Modern Techniques in Biotechnology”.  HybriGene has a commitment to responsible environmental biotechnology and education.

 Ophios LLC

An Agri-Food Production Company (SOLD-2012)

Peter Sellew,AmolDeshpande, andAlbert Kausch

Ophios, LLC is a vegetable produce company that has developed a new garlic vegetable called Baby Green Garlic. This new product grows and is similar in appearance to a scallion, and is meant to be consumed fresh as a green vegetable. The popularity of garlic is on the rise in the U.S.  Consumption of garlic in the US has risen from ½ pound per person in 1985 to 3.1 pounds per person in 1999. Of the total garlic harvested in the US, 60% is dehydrated, 30% is sold fresh, and 10% is processed for oil. Garlic is an excellent crop to promote as a local specialty. It can be sold in a number of forms for a number of uses. The major business objectives of Ophios are as follows: I). Develop cost effective technologies to produce large scale amounts of baby green garlic year round as a new commercial market for grocery stores, nurseries and farmers II). Identify gourmet hardneck garlic varieties as a specialty crop from and file Plant Variety Protection (PVP) patents to secure licensing rights; III). Develop capabilities to create new garlic varieties using advanced plant breeding, transgenic and other biotechnology approaches

Ophios has introduced Baby Green Garlic as a new vegetable commodity, comparable to green onions or scallions, except with a mild garlic flavor.  The plants appear similar to their onion relatives, also having a whitish bulb at the base of the plant instead of the familiar garlic cloves of a mature plant.  Ophios has developed and patented a system to produce large scale amounts of green garlic that will be packaged and sold as fresh produce in grocery stores.  We intend to produce young shoots that will be packaged as garlic sprouts, as well as scallion, and leek-sized green garlic that will be packaged and sold as fresh produce in grocery stores. Baby Green Garlic is currently sold on a very small scale and only as a seasonally because the limited production capability of current growers. Our production approach allows reliable year round supplies.  We think this new vegetable will be well received.

The company has been funded through both invested capital and in-kind contributions from founders as well as seed venture capital from the Slater Fund inRhode Island.  The company has also received non-dilutive business development funds from a large corporate partner.  The total capital and in-kind contributions to the company have been in excess of $1M over the past 3 years.  Ophios products are protected through both filedUnited Statespatents as well as trade secrets. Baby Green Garlic was identified through varietal selection coupled with optimization for large scale greenhouse and outdoor growth conditions.  The intellectual property is based upon the novel approach of using bulbils as a starting point for commercial green garlic production and the methods and compositions for large scale production.  Baby Green Garlic is a new vegetable ready for commercial production. Ophios continues to develop new ideas and trade secrets.  The company has filed a series of provisional patents to further protect novel new product developments that could be pursued with additional funding.   The company intends to continue to vigorously protect its ideas and markets through use of patents and trade secrets.

The series of pictures below give an idea of differences between the outdoor and greenhouse product.  Additional pictures of some initial marketing concepts are also included.  The company has developed and marketed these products differently.  The company also believes this allows for a tremendous advantage in being able to introduce a series of highly profitable products from one technology platform.

Baby Green Garlic as a New Vegetable Crop. (far left) Outdoor production (A&B) Greenhouse grown  plants (C) Label that is now used to sell the product in retail grocery chains.

Baby Green Garlic is distinct from the rest of the members of the Onion Family as a separate new crop produced as young plants from the bulbils of specific hardneck garlic varieties. While the plants appear more slender than their scallion relatives, they also have a whitish bulb at the base of the green plant instead of the familiar garlic cloves of a mature plant, and they taste like garlic. Ophios has used a varietal selection procedure and a commercial production approach that has allowed large reliable year round supplies of a scallion-like Baby Green Garlic as a new vegetable green.

What has Ophios done to enable cultivation of green garlic as a new vegetable?

  • Understand green garlic production methods relative to existing products (such as green onions).
  • Identified significant and consistent supply of rare bulbils for large scale production.
  • Solved the problems of how to logistically and scientifically product green garlic commercially.
  • Develop methods and competency in bulbil-based propagation and production.
  • Document and learn the first fresh green garlic production methods.
  • Developed expertise with varietal screening to potentially develop new garlic vegetable products in the future.
  • Developed ideas and methods for smaller scale localized production, both in-greenhouse and outdoors.
  • Demonstrate market interest from both food service and grocery markets
  • Demonstrate high price points and compelling profit margins relative to the vegetable industry at large.

The ability to produce Baby Green Garlic as a new vegetable crop is an exciting opportunity that can be expanded with additional varieties with improved characteristics.  The popularity of garlic is on the rise in the U.S. where per capita consumption has increased more than 10-fold from a meager 0.3 pounds per person per year in 1971 to 3.3 lbs per capita/yr in 1999 (USDA).  Baby Green Garlic as a new vegetable has already been well received in our debut in the marketplace, including a 3 month stint in Price Chopper stores in theNortheast United States.  The versatility of the product allows it to take market share from Onions, Garlic and Scallions while also creating a new market unto itself.  The aggregate market opportunity for Baby Green Garlic between substitution and new market creation is in excess of $1.3 B.

What is the Fresh Green Garlic market concept?

  • Use of fresh green onions is well established, this is a better alternative
  • This is a superior product to traditional garlic, with a more subtle flavor and even more uses
  • Use of fresh green garlic is comparable to both green onions and garlic, but provides a new product concept with completely new uses
  • Green garlic provides a fresh presentation of allicin and can be marketed for potential health benefits with realistic expectations
  • There are multiple opportunities for differentiated fresh produce items and can be marketed in different ways

Ophios is currently in discussion with large major vegetable production companies to commercialize this product.

 

Plant Advancements, Inc.

Biomass Products andSuperiorGermplasm for the Bioenergy Industry

Plant Advancements, LLC, in association with Ernst Conservation Seeds Inc., is a renewable bioenergy company with a focus on the development and primary production of biomass for the growing bioenergy industries. Recognizing the need for dedicated energy crop development, Plant Advancements research is developing new elite and improved varieties of switchgrass and other dedicated energy crops and products used for bioenergy.  The broad mission of the company is use conventional breeding, genomics, advanced breeding, and biotechnology to produce new varieties that will provide sustainable solutions for bioenergy industries. Plant Advancements has designed proprietary gene confinement hybrid systems as operating platforms that will be required for regulatory and environmental stewards for the deployment of genetic modification for enhancing biofuel production and encourages collaborations. 

Energy from biomass, particularly cellulosic biomass from dedicated energy crops, will have tremendous economic, environmental and national security benefits.  Biofuels will help alleviate our national dependency on fossil fuels, with a cost savings of an estimated $20 billion per year based on 2050 estimated fuel costs. By 2025, producing biofuel crops will generate over $5 billion per year in farm profits while reducing greenhouse gas emissions by more than 80% in the transportation related sector. The nation currently uses almost 7 billion gallons of ethanol a year – produced primarily from corn kernels – this represents less than 2% of our current total fuel use in the transportation sector. Large increases in corn ethanol production will tax productive farmlands, place additional pressure on scare water resources, and compete with our nation’s food supply. Clearly cellulosic energy technologies will continue to emerge as the key technology in reducing our nation’s oil dependency. In August 2005, Section 942 of the U.S. Energy Policy Act mandated an annual production of 250 million gallons of cellulosic ethanol by 2013, and a goal of 1 billion gallons annually by 2015. For this realization, however, substantial improvements of biomass yields of perennial grasses will be essential for efficient large-scale cellulosic biofuel production.

 

Plant Advancements has formed The Bioenergy Consortium to accomplish these goals. This organization includesYaleUniversity, theUniversityofRhode Island, theUniversityofConnecticut, and Ernst Conservation Seeds, Inc.  Plant Advancements has a collaborative agreement with Ernst Conservation Seeds Inc., who specializes in the production of native and naturalized seeds and plant material of Eastern North American ecotypes, and is currently the largest producer of commercial seed for switchgrass and related bioenergy grasses in the world. Plant Advancements, with Ernst, is the commercializing arm of the Bioenergy Consortium, and is situated to be the largest supplier of switchgrass as raw materials for the bioenergy industry.

 

Plant Advancements currently has an immediate product line and a revenue stream, through its association with Ernst Conservation Seed Inc., for contract production of biomass for biorefineries.  Sales of switchgrass seed are increasing and expected to dramatically increase as the need for raw biomass increases as cellulosic biorefineries come on line. Seed sales are increasing to farmers for biomass production directly. Plant Advancements purchases seed for contract biomass production through Ernst Conservation Seed Inc. and products such as bulk, pulverized, pelletized, and densified switchgrass are be produced by Plant advancements and marketed to biorefineries.  In addition, biorefineries can contract Plant Advancements and Ernst for the production of biomass products.

 

The near-term product goals (1-3 yrs) for Plant Advancements include the development of improved and regionally selected varieties through conventional breeding. Ernst Conservation Seeds and Plant Advancements will co-develop new varieties for production and PVP protection for licensing and release as foundation material. Ernst Conservation Seeds and Plant Advancements will identify production and quality traits of regional cultivars. All lines that are developed by this collaboration are the property of Plant Advancements, with exclusive rights to license these lines for the third party commercial production. Ernst will have exclusive access to these varieties for the production of genetically modified transgenic plants both within the company and through its collaborators.

In collaboration withYaleUniversity, Plant Advancements will establish a robust marker-assisted breeding (MAB) program to accelerate new variety development and identify bioenergy traits. Most of the traits of interest to bioenergy crop improvement are multi-geneic; therefore, the use of marker-assisted breeding will significantly shorten the time to commercialize and characterize the plants for PVP protection. Plant Advancements has also established an exclusive arrangement with theUniversityofRhode Islandto innovate new developments in the area of bioenergy crop improvement. As part of that agreement, Plant Advancements has access to the Plant Biotechnology Laboratory (PBL) inWest Kingston,RI.  This facility also serves as an off-campus incubator space for Plant Advancements. The collaboration is currently seeking to fill positions at various levels.  All agreements with outside companies, including collaborations, partnerships, and contracts, will be with Plant Advancements.

Plant Advancements is seeking to develop a network of collaborators from industry, academics, and government to achieve these goals. We recognize the commercial constraints (Freedom to Operate and licensing issues) and, ideally, we propose to work together to resolve those needs for the development of commercially viable systems and products with improved traits for the bioenergy industry. Plant Advancements can provide industrial collaborators with:

1. Immediate biomass production

2. Access to newly developed varieties that have been regionally selected for optimal growth throughout North America for introgression of transgenic traits.

3. Availability of commercial development, marketing, and distribution of genetically improved varieties through the collaboration between Plant Advancements and Ernst Conservation Seeds.

4. Access to the hybrid switchgrass platform for total sterility that is currently being developed by Plant Advancements.

5. Access to the genomics platform and marker-assisted breeding for rapid introgression of trait genes into commercial switchgrass varieties.

6. Access to transgenic capabilities and facilities through the Plant Advancements/University of Rhode Island collaboration.

 

Collaboration between Plant Advancements and other companies will allow the deployment of trait genes important to improved bioenergy crops and commercialization and marketing of new varieties. In addition, Plant Advancements is seeking corporate collaborators who have Freedom to Operate with various technologies to co-develop and commercialize products. Plant Advancements aggressive business strategy is a three-year commercialization window to profitability based on the existing sales, switchgrass germplasm, and the future sale of new varieties with improved bioenergy traits. The high probability of commercial success of Plant Advancements is rooted in our exclusive commercial joint venture with Ernst Conservation Seeds Inc. and the Bioenergy Consortium. Plant Advancements is currently seeking investment partners to develop the business in response to a rising demand for renewable biomass that will serve the bioenergy industry for the foreseeable future.

 

lifeedu.us

A Non-Profit Organization Dedicated to Production of Educational Materials on Biotechnology

     lifeedu (pronounced, life e-d-u) is a nonprofit organization established for the creation, production, and distribution of educational materials onDNA, genetics, and modern biotechnology for middle school, high school, general undergraduate and the general public. The organization was founded to meet a growing educational need that is fundamental to the life sciences and the general education of our society.

        Currently, there is a wide disparity between the knowledge of the general public about DNA and biotechnology and the actual science and its’ applications. This gap is growing wider every day and has created a current educational crisis about DNA, how life works and biotechnology.  This lack of fundamental knowledge has resulted in much uninformed debate and even protests about biotechnology.

The goal of lifeedu is to bridge this gap in understanding and fundamentally change the way people think about life.  The biological, health, and environmental sciences have been rapidly transformed by the introduction of DNA-based technologies that allow for the precise manipulation and examination of the genetic material of plants, animals, humans, and microbes.  The advancements have been so rapid and extensive and have far exceeded the public knowledge base that crucial decisions are being made by default.  Embryonic stem cell research, cloning, genetically modified organisms (GMOs) in food, genomic research and informed consent, are current controversies.  The tools of biotechnology are currently being applied across the biological sciences to address problems in medicine, pharmacy, agricultural crop improvement, marine sciences and aquaculture, forensics, bioterrorism and public health.  The introduction of this field has been extremely rapid and has created a tremendous educational need to keep pace. A working knowledge of DNA, genetics, and biotechnology has become as fundamental to a basic education as an understanding of the solar system.  The more our society understands the fundamentals the better equipped they will be to participate, affecting career opportunities, economic development, policy and decision making, as well as general consumer education in a life long learning process.  lifeedu is dedicated to the production and development of the most reliable, comprehensive and accessible educational materials about biotechnology.  Educational kits and materials are developed in a modular approach that is auto-tutorial for both teachers and students and is fully up-datable.

lifeedu has established a broad base of industry, academic, and government support and expertise. Our highly respected Founding Board of Directors has enabled us to attract a diverse group of talented experts.

This Founding Board of Directors initiated the program and aims to be integral in biotechnology education in the State of Connecticut and nationwide and includes the following individuals:  Directors: Albert Kausch, Ph.D. University of Rhode Island, Stephen Dellaporta, Ph. D. Yale University Elora Weringer, Ph.D. Pfizer, Inc. President, Albert Kausch, Ph.D. Co- Vice Presidents, Bioethics; Lynn Pasquerella, Ph.D. Lawrence Rothstein, Ph.D. University of Rhode Island, Vice President, Middle School and High School Curriculum Reform David Moss, Ph.D. University of Connecticut, Vice President, General and Undergraduate Education Development  T. Page Owen. Jr., Ph.D. Connecticut College Vice President, Training Program Development  Gregory Paquette, Ph.D., CLS, University of Rhode Island, Vice President, Marine Biotechnology Education Marta Gomez-Chiarri, Ph.D. University of Rhode Island, Vice President, Vocational Agricultural Education, Govind Sharma, Ph.D. Alabama A&M University, Vice President, E-Learning and Biopharmaceutical Corporate Liaisons, Paul A. Armond, Ph.D. Pfizer, Inc. Vice President, Multimedia Productions, Chip Longo

                        lifeedu makes educational materials on biotechnology, such as CD-ROMs, DVDs, videos, textbooks, written lesson plans, demonstrations, kits, and other materials to facilitate teaching and information transfer about DNA, genetics and biotechnology.  We believe it is now necessary to involve these materials and approaches throughout the life long learning educational sectors with an emphasis on introducing these materials early and throughout the education process.  Help us change the future.

 

lifeedu.us

President and Founder

                                                Albert P. Kausch

 

 

 

AWARDS

 

2013 Society for In Vitro Biology Distinguished Service Award

2013 University of Rhode Island Inventor of  The Year Award

2011 Massachusetts Horticultural Society  Distinguished Scientist Award

2009 University of Rhode Island Innovator of the Year Award

1983 Iowa State University Summa cum Laude

1980 Iowa State University Summa cum Laude

1978 State University of New York  Magnum cum Laude

1978 State University of New York  Martin V. Torok Outstanding Biology Student of the Year Award


II. Publications and creative works

 

A.      Thesis titles

 

Ph.D., 1983.  Development, physiology, and function of selected plant raphide crystal idioblasts.

 

M.S., 1980. A light and electron microscope study of the development and  function of raphide crystal idioblasts in young leaves of Typha angustifolia L.

 

B.     Published  micrographs

 

Dolphin, W.D. 1983. Biology. Wm. C. Brown Publ.,Dubuque,IA.

 

Dolphin, W.D. 1983. Biology  Laboratory  Manual. Wm. C. Brown Publ. ,Dubuque,IA.

 

C.   Published abstracts and meeting presentations:

 

Dr. Kausch has published over a hundred and twenty abstracts for meetings and poster presentations at state, national, and international conferences since 1980 (titles available on request).

 

D.     Research Publications

 

1. Kausch, A.P., J.L. Seago, and L.C. Marsh.  1981.  Changes in starch distribution in the over wintering organs of Typha latifolia (Typhaceae).  Amer. J. Bot. 68:877‑880.

 

2. Kausch, A.P. and H.T. Horner, Jr.  1981.  The relationship of air space formation and calcium oxalate crystal development in young leaves of Typha angustifolia L. (Typhaceae). Scanning Electron Microscopy III: 263‑272.

 

3. Horner, H.T., A.P. Kausch, and  B.L. Wagner.  1981.  Growth and change in shape of raphide and druse calcium oxalate crystals as a function of intracellular development  in  Typha angustifolia L. (Typhaceae) and Capsicum annum  L. (Solananceae).  Scanning Electron Microscopy III:251‑262.

 

4. Kausch, A.P. and H.T. Horner.  1982.  A comparison of calcium oxalate crystals from callus cultures and their explant sources.  Scanning Electron Microscopy I: 199‑211.

 

5. Kausch, A.P. and  H.T. Horner.  1983.  The development of mucilaginous raphide crystal idioblasts in young leaves of Typha angustifolia L. (Typhaceae). Amer. J. Bot. 70:691‑705.

 

6. Kausch, A.P. and H.T. Horner.  1983.  The development of synctial raphide crystal idioblasts in aerial roots of Vanilla planifolia L. Scanning Electron Microscopy II:893‑903.

 

7. Kausch, A.P., B.L. Wagner and H.T. Horner.  1983.  Use of the cerium chloride technique and energy dispersive x‑ray microanalysis to allow plant peroxisome identification. Protoplasma 118:1‑9.

 

8. Kausch, A.P. and H.T. Horner.  1984.  Increased nuclear DNA content during raphide crystal idioblast development in Vanilla planifolia L. European J. Cell Biology 33:7‑12.

 

9. Kausch, A.P. and H.T. Horner.  1984.  Differentiation of raphide crystal idioblasts in isolated root cultures of Yucca torreyi L. (Agavaceae). Can. J. Bot. 62 (7):1474‑1488.

 

10. Kausch, A.P.  1984.  The biogenesis and cytochemistry of unspecialized peroxisomes in root cortical cells of Yucca torreyi.  European J. Cell Biology 34:239‑247.

 

11. Kausch, A.P. and  H.T. Horner.  1985.  Absence of CeCl3 detectable glycolate oxidase activity in developing calcium oxalate raphide crystal idioblasts of Psychotria punctata and Yucca torreyi.  Planta 164:35‑40.

 

12. Kausch, A.P.  1985.  Peroxisomal enzyme cytochemistry by cerium precipitation.  In Handbook for Plant Histochemistry. K.C. Vaughn, Ed. CRC Press, Inc.

 

 

13. Timko, M., A.P. Kausch, L. Herrera‑Estrella, G. Van den Broeck, M. Van Montagu, and  A.R. Cashmore.  1985.  The structure and expression of nuclear genes encoding polypeptides of the photosynthetic apparatus.  In: The Molecular Biology of the Photosynthetic Apparatus.  C.  Arntzen,  L. Bogorad, S. Bonitz, and K.SteinbackEds.ColdSpringHarborPress.

 

14. Herrera‑Estrella, L.G. Van den Broeck, M. Timko, A. Kausch, A. Cashmore, J. Schell, and M. Van Montagu.  1985.  The use of chimeric genes to study the light‑inducible gene expression of chloroplast import of the small‑subunit of ribulose‑1,5‑biphosphate carboxylase.  In The Molecular Biology of the Photosynthetic Apparatus.  C. Arntzen, L. Bogorad, S. Bonitz, and K. Steinback,Eds.ColdSpringHarbor.

 

15. Van den Broeck, G., M.P. Timko, A.P. Kausch, A.R. Cashmore, M. Van Montagu, and L. Herrera‑Estrella.  1985.  Targeting of a foreign protein to chloroplasts by fusion to the transit peptide from the small subunit of ribulose‑1,4‑biphosphate carboxylase.  Nature 313:358‑363.

 

16. Timko, M.P., A.P. Kausch, C. Castresana, J. Fassler, L. Herrera‑Estrella, G. Van den Broeck, M. Van Montagu, and A.R. Cashmore.  1985.  Expression of RuBP carboxylase small subunit genes involves sequences with enhancer‑like properties.  In Plant Genetics,  UCLA Symposia on Molecular and Cellular Biology, New Series, Volume  35,  (ed., M.  Freeling),  Alan R. Liss, Inc.,New York.

 

17. Cashmore, A., L. Szabo, M. Timko, A. Kausch, G. Van den Broeck, P. Schreier, H. Bohnert, L. Herrera‑Estrella, M. Van Montagu, and J. Schell.  1985.  Import of polypeptides into chloroplasts.  Bio/Technology 3:803‑808.

 

18. Pichersky, E., R. Bernatsky, S. Tanksley, R.W. Breidenbach, A.P. Kausch and A.R. Cashmore.  1985. Molecular characterization and genetic mapping of two clusters of genes encoding chlorophyll a/b binding proteins in Lycopersicon esculentum (tomato).  Gene 40:247-258.

 

19. Timko, M.P., A.P. Kausch, C. Castresana, J. Fassler, L. Herrera‑Estrella, G. Van den Broeck, M. Van Montagu, and A.R. Cashmore, 1985.  An enhancer‑like element mediates  light‑inducible ribulose‑1,5‑biphosphate carboxylase small subunit gene expression. Nature (Lond.) 318:579‑582.

 

20. Smereka, K.J., W.E. MacHardy, and A.P. Kausch.  1987.  Cellular differentiation  of  Venturia inaequalis ascospores during germination and penetration of apple leaves.Can.J. Bot. 65:2549‑2561.

 

21. Smereka, K.J., A.P. Kausch and W. E. MacHardy.  1988. Intracellular junctional structures in the fungus Venturia inaequalis.  Protoplasma 142:1‑4.

 

22. Gordon‑Kamm, W.J., T.M. Spencer, M.L. Mangano, T.R. Adams, R.J. Daines, W.G. Start, J.V. O’Brien, S.A. Chambers, W.R. Adams, Jr., N.G. Willetts, T.B. Rice, C.J. Mackey, R.W. Krueger, A.P. Kausch, and 23. 23. P.G. Lemaux.  1990.  Transformation of maize cells and regeneration of fertile transgenic plants.   The Plant Cell 2:603‑618.

 

24. Gordon‑Kamm, W.J., T.M. Spencer, M.L. Mangano, T.R. Adams, R.J. Daines, W.G. Start, J.V. O’Brien, S.A. Chambers, W.R. Adams, Jr., N.G. Willetts, T.B. Rice, C.J. Mackey, R.W. Krueger, A.P. Kausch, and P.G. Lemaux. 1991. Transformation of Maize Using Microprojectile  Bombardment:  An Update  and Perspective. In Vitro Cell. Dev. Biol. 27:21‑27.

 

25. Mackey, C. J., T. M. Spencer, T. R. Adams, A. P Kausch, W. J. Gordon-Kamm, P. G. Lemaux, and R. W. Kreuger.  1992. Transgenic Maize.  in Transgenic Plants, Vol. 2. H. C. Kung and K C. Wu Eds. Academic Press, Inc.San Diego,CA

 

26. Kausch, A.P. and B.D. Bruce.  1994.  Isolation and immobilization of various plastid subtypes by magnetic immunoabsorption. The Plant Journal  6 (5) 767-779.

 

27. Kausch, A.P., T. R. Adams, M.L. Mangano, S. Zachwieja, N. G. Willetts, S. A. Chambers, W. Adams, Jr., Amy Anderson, Geoff Williams, G. Haines. 1995.  Effects of microprojectile bombardment on embryogenic suspension cell cultures of maize (Zea mays L.) used for genetic transformation. Planta 196: 501-509.

 

28. Sonti, Srinivas, Matthew Griffor, Takeshi Sano, Sandya Narayanswami, Arijit Bose, Charles Cantor, and Albert P. Kausch. 1995. Large Scale Isolation of plant expression cassette by magnetic triple helix affinity capture. Nucleic Acids Research 23:19.

 

29. Kausch, A.P., T.P. Owen, and B.D. Bruce. 1999. Organelle Isolation By Magnetic Immuno-absorption. Biotechniques Vol. 26:336-343.

 

30. Knapp, J., Kausch, A.P., and J. Chandlee. 2000. Stable Transformation of three genera of Orchids. Plant Cell Reports 19: 893-898.

 

31. Horner, H.T., A.P. Kausch, and B.L. Wagner. 2000. Ascorbic acid serves as precursor for oxalate synthesis in calcium oxalate idioblasts of Yucca torreyi in liquid root cultures. International Journal of Plant Sciences 161 (6):861-868.

 

32. Kausch, A.P., T. Page Owen, S. Zachweija, Adam R. Flynn, and J. Sheen 2001. Mesophyll specific, light and metabolic regulation of the C4 PPCZm1 promoter in transgenic maize. Plant Molecular Biology 45 (1) 1-16.

 

33. Knapp, J., Kausch, A.P., Auer, C. and M. Brand. 2001. Transformation of Rhododendron through Microprojectile Bombardment. Plant Cell Reports 20:749-754.

 

34. Luo, Hong  and Albert P. Kausch  (2002) Application of FLP/FRT site-specific DNA recombination system in plants. In Genetic Engineering, Principles and Methods, Vol. 24, Setlow JK (ed.), Kluwer Academic/Pleum Publishers, New York, NY, pp.1-16.

 

35. Wang, Y. B. Ruemmele, J. Chandlee, M. Sullivan, J. Knapp. andAlbert Kausch. 2002 Embryogenic callus induction and plant regeneration media for bentgrasses and annual bluegrass. In Vitro Biol. 38:460-467

 

36. Wang, Y., M. Browning, B. Ruemmele, J. Chandlee,Albert Kausch, and NoelJackson. 2003 Glufonsinate reduces fungal diseases in transgenic glufosinate-resistant bentgrasses.  Weed Science 51:130-137.

 

37. Basu, C., Kausch, A.P. Luo, H., and  J. Chandlee 2003. Promoter analysis in transient assays using a GUS Reporter gene construct in creeping bentgrass (Agrostis palustris, L.) Journal of Plant Physiology 160:1233-1239.

 

38. Basu, C., Kausch, A.P. Luo, H., and  J. Chandlee 2003 Transient reporter (GUS) expression in creeping bentgrass (Agrostis palustris) is affected by in vivo nucleolytic activity. Biotechnology Letter 25:939-944.

 

39. Wang, Yuexia Albert P. Kausch, Hong Luo, Joel M. Chandlee, B.A. Ruemmele, M. Browning, N. Jackson and M. R. Goldsmith (2003) Co-transfer and expression of chitinase, glucanase, and bar genes in creeping bentgrass for conferring fungal disease resistance. Plant Science 165:497-506.

 

40. Luo, Hong Qian Hu, Kimberly Nelson, Chip Longoand Albert P. Kausch (2003) Controlling transgene escape in genetically modified grasses. In: Molecular Breeding of Forage and Turf,Hopkins A, Wang ZY, Mian R, Sledge M and Barker R (eds.), Kluwer Academic Publishers.

 

41.  Hong Luo, Qian Hu, Kimberly Nelson, Chip Longo, Albert P. Kausch, Joel M. Chandlee, Joseph K. Wipff and Crystal Rose Fricker (2004) Agrobacterium tumefaciens-mediated creeping bentgrass (Agrostis stolonifera L.) transformation using phosphinothricin selection results in a high frequency of single-copy transgene integration. Plant Cell Reports 22:645-652.

 

42. Hong Luo, Qian Hu, Kimberly Nelson, Chip Longo and Albert P. Kausch (2004) Controlling transgene escape in genetically modified grasses. In: Molecular Breeding of Forage and Turf, Hopkins A, Wang ZY, Mian R, Sledge M and Barker R (eds.), Kluwer Academic Publishers, Dordrecht/Boston/London, pp. 245-254.

 

43. Melvin J. Oliver, Hong Luo, Albert Kausch, Harry Collins(2004) Seed-based strategies for transgene containment. In: Proceedings of 8th International Symposium on the Biosafety of Genetically Modified Organisms, International Society for Biosafety Research (ISBR), September 26-30, 2004, Montpellier, France, pp. 154-161.

 

44. Hong Luo, Qian Hu, Kimberly Nelson, Chip Longo, Joel M. Chandlee and Albert P. Kausch, (2005) Agrobacterium tumefaciens-mediated turfgrass transformation. In: Methods in Molecular Biology – Agrobacterium Protocols (2nd edition), Wang K (ed.) The Humana Press Inc.,Totowa,NJ

 

45. Hong Luo, Albert P. Kausch, Qian Hu, Kimberly Nelson, Joseph K. Wipff, Crystal C. R. Fricker, T. Page Owen, Maria A. Moreno, Jang-Yong Lee and Thomas K. Hodges (2005) Controlling transgene escape in GM creeping bentgrass. Molecular Breeding 16:185-188.

 

46. Hong Luo, Jang-Yong Lee, Qian, Hu, Kimberly Nelson, Albert P. Kausch, Joel M. Chandlee, Tim K. Eitas, Collin Lickwar, Thomas K. Hodges (2006) RTS, an anther-specific gene isolated from rice is required for male fertility and its promoter sequence directs tissue-specific transcription in dicotyledonous species. Plant Molecular Biology 62:397-408.

47. Chip Longo, Colin Lickwar, Qian Hu, Kimberly Nelson, David Viola, Joel Hague, Joel M. Chandlee, Hong Luoand Albert P. Kausch, (2006) Turfgrasses. In: Methods in Molecular Biology – Agrobacterium Protocols, Vol. 344:Agrobacterium Protocol, 2/e, Vol. 2, Wang K (ed.) Humana Press Inc., Totowa, NJ, pp. 83-95

48.Kausch, AP.,  K. Nelson-Vasilchik, J.M. Chandlee, and H. Luo. 2006. Methods and Compositions for increasing biomass in genetically modified perennials used for biofuels. This application claims priority to USPTO  Provisional Application No. 60/808,074 filed on May 24, 2006, Assignee: The University of Rhode Island

 

49.Qian Hu, Halina Kononowicz-Hodges, Kimberly Nelson-Vasilchik, David Viola, Peiyu Zeng, Haibo Liu, Albert P. Kausch, Joel M. Chandlee, Thomas K. Hodges, Hong Luo(2007) FLP-mediated site-specific recombination in rice.  Plant Biotechnology Journal 6:2:176-188

 

50.  Albert P. Kausch*, Joel Hague, Melvin Oliver, Yi Li, Henry Daniell, Peter Mascia, and C. Neal Stewart Jr.  Genetic Modification in Dedicated Bioenergy Crops and Strategies for Gene Confinement in P.N. Mascia et al. (eds.), Plant Biotechnology for Sustainable Production of Energy and Co-products, Biotechnology in Agriculture and Forestry 66, DOI 10.1007/978-3-642-13440-1_10 Springer-Verlag Berlin Heidelberg 2010

51. Albert P. Kausch* Joel Hague, Melvin Oliver, Lidia S. Watrud, Carol Mallory-Smith, Virgil Meier, and C. Neal Stewart Jr. 2010. Gene Flow in Genetically Engineered Perennial Grasses: Lessons for Modification of Dedicated Bioenergy Crops in P.N. Mascia et al. (eds.), Plant Biotechnology for Sustainable Production of Energy and Co-products, Biotechnology in Agriculture and Forestry 66, DOI 10.1007/978-3-642-13440-1-10 Springer-Verlag Berlin Heidelberg  2010

52. Kausch, A. P*., J. Hague, M. Oliver, Y. Li, H. Daniell, P. Mascia, Watrud L. S., and C.  Neal Stewart Jr. 2010. Transgenic perennial biofuel feedstocks and strategies for bioconfinement. Biofuels 1(1):163-176.

53. Moon, H., J. Abercrombie, A. Kausch, and C. Stewart. 2010. Sustainable Use of Biotechnology for Bioenergy Feedstocks, pp. 1-8 Environmental Management. SpringerNew York.

 

54. Male Sterility and Hybrid Plant Systems for Gene Confinement Albert P. Kausch*, Joel Hague, Adam Deresienski, Michael Tilelli, Chip Longo Jr. and Kimberly Nelson. 2012 Plant Gene Confinement EDS Melvin Oliver and Yi Li. Wiley-Blackwell John Wiley & Sons MA .

 

55. Joel P. Hague, Steven L. Dellaporta, Maria Moreno, Chip Longo, Kimberly Nelson, Albert P. Kausch (2012).  Pollen Sterility – A Promising Approach to Gene Confinement and Breeding for Genetically Modified Bioenergy Crops. Agriculture 2:295-315

 

56. Kausch, AP, Hague, J, Deresienski A, Tilelli M,  Longo C, and Nelson, K (2013) Issues in Biotechnology: A Massive Open Online Course (MOOC) Covering in Simple Terms Basic Knowledge About DNA and Biotechnology INTED Proceedings.

 

57. Kausch, AP, Deresienski A, Hague, J, Tilelli M, Dellaporta SD, Nelson, K  and Li,Yi. (2013) Hybrid Plant Systems for Breeding and Gene Confinement in Bioenergy Crops. In: New and Future Developments in Catalysis – Catalytic Biomass Conversion. Steven Suib,  Ed.  Elsevier Press (in press)

 

58. Nelson, K., A. Deresienski, M. Tilelli, J. Hague, C. Longo and A.P. Kausch.  (2013) In situ embryo rescue in Switchgrass (Panicum virgatum L.) and ‘Atlantic’ Coastal Panicgrass (Panicum virgatum Ell. var. amarulum) Plant Science (submitted)

 

59.  Howard, TP, Tordillos, A, Fragoso, C., Moreno, MA, Mottinger, JP, Kausch, AP, Tohme, J, and Dellaporta, SL (2013) Identification of the maize gravitropism gene lazy plant1 by a transposon-tagging genome resequencing strategy.  Genetics, submitted.

 

 

60 . Deresienski, A., K. Nelson, J. Hague, M. Tilelli, C. Longo, and A.P. Kausch. Male sterility in switchgrass (Panicum virgatum L.) BioEnergy Research  (In preparation)

 

61.  C. Heffelfinger,   Dellaporta,  S. , Moreno, M.  Deresienski, A., K. Nelson, J. Hague, and A.P. Kausch. Production and Genomic Analysis of Interspecific Hybrids in Switchgrass (Panicum virgatum, L.).  Nature Biotechnology (In preparation).

 

62. Deresienski, A., K. Nelson, J. Hague, and A.P. Kausch. Production of intraspecific and interspecific hybrids in switchgrass (Panicum virgatum).  Crop Science (In preparation)

 

 

  1. E.      Biotechnology Related Patents

 

1. 1985. Targeting of foreign proteins to chloroplasts by chimeric gene constructions encoding transit peptides.  Plant Genetic Systems (Issued: applicant).  European Patent Office.  Co‑inventors L. Herrera‑Estrella, G. Van den Broeck, P. Schreier, H.J. Bohnert, A.R. Cashmore, M. Timko, A.P. Kausch, J. Schell. (Plant Genetic Sciences (PGS),GhentBelgium: assignee)

 

2. 1988 A method for molecular transformation of Pisum sativum. Albert P. Kausch; Del Monte Corp. (applicant). 1988USAPatent Office.

 

3. 1996 Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof. Thomas R Adams, Sheryl A. Chambers, Richard J. Daines, William J. Gordon-Kamm, Albert P. Kausch, Peggy G. Lemaux, Catherine J. Mackey, Mary L. Mangano, James V. O’Brien, Thomas B. Rice, T. Michael Spencer, William G. Start, Nancy G. Willetts. Assignee: DEKALB Plant Genetics (Issued: August 27, 1996).USAPatent Office. Patent Number 5,550,318.

 

4. 1996 Isolation of biological materials using magnetic particles. Albert P. Kausch, Sandya Narayanswami, Jerry E.  Manning,  Barbara  Hamkalo; Assignee: DEKALB Plant Genetics (Issued: April 16, 1996) applicant). USAPatent Office. Patent Number 5,508,164.

 

5. 1996 Process of producing fertile transgenic Zea Mays plants and progeny comprising a gene encoding phosphinothricin acetyl transferase. Thomas R Adams, Sheryl A. Chambers, Richard J. Daines, William J. Gordon-Kamm, Albert P. Kausch, Peggy G. Lemaux, Catherine J. Mackey, Mary L. Mangano, James V. O’Brien, Thomas B. Rice, T. Michael Spencer, William G. Start, Nancy G. Willetts. Assignee: DEKALB Plant Genetics (Issued: February 6, 1996).USAPatent Office. Patent Number 5,489,520.

 

6. 1997 Isolation of biological materials. Albert P. Kausch and Sandya Narayanswami Assignee: DEKALB Plant Genetics (Issued: September 9, 1997)USAPatent Office. Number 5,665,582

 

7. 1998 Chimaeric gene coding for a transit peptide and a heterologous peptide. L. Herrera‑Estrella, G. Van den Broeck, M. Van Montague, P. Schreier, J. Schell, H.J. Bohnert, A.R. Cashmore, M. Timko, A.P. Kausch,. Assignees : Plant Genetic Sciences (PGS),GhentBelgium; and, Bayer A.G.Leverkusen.  (Issued February 10, 1998)USAPatent Office. Number 5,717,084

 

8. 1998 Transgenic maize with increased mannitol content. T. R. Adams, P. C. Anderson, R. J. Daines, W. Gordon-Kamm, A. P. Kausch, M. T. Mann, P. M. Orr, D. C. Warner. Assignee: DEKALB Genetics Corporation (Issued: July 14, 1998).USAPatent Office. Number 5,780,709

 

9. 1998 Chimaeric gene coding for a transit peptide and a heterologous polypeptide. L. Herrera‑Estrella, G. Van den Broeck, M. Van Montague,  P. Schreier, J. Schell, H.J. Bohnert, A.R. Cashmore, M. Timko, A.P. Kausch. Assignees : Plant Genetic Sciences (PGS),GhentBelgium; and, Bayer A.G.Leverkusen.  (Issued March 17, 1998)USAPatent Office. Number 5,728,925

 

10. 1998 USA Patent application *(Improved method for plant transformation) Albert P. Kausch , Dennis R. Genovesi, Susan Zachweija Thomas R Adams, Sheryl A. Chambers , Mary L. Mangano, T. Michael Spencer. Applicant: DEKALB Plant Genetics.

 

11. 1999 Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof. Thomas R Adams, Sheryl A. Chambers, Richard J. Daines, William J. Gordon-Kamm, Albert P. Kausch, Peggy G. Lemaux, Catherine J. Mackey, Mary L. Mangano, James V. O’Brien, Thomas B. Rice, T. Michael Spencer, William G. Start, Nancy G. Willetts. Assignee: DEKALB Plant Genetics (Issued: February 23, 1999).USAPatent Office. Patent Number  5,874,265

 

12. 1999 Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof. Thomas R Adams, Sheryl A. Chambers, Richard J. Daines, William J. Gordon-Kamm, Albert P. Kausch, Peggy G. Lemaux, Catherine J. Mackey, Mary L. Mangano, James V. O’Brien, Thomas B. Rice, T. Michael Spencer, William G. Start, Nancy G. Willetts. Assignee: DEKALB Plant Genetics (Issued: July 6, 1999).USAPatent Office. Patent Number  5,919,675

 

13. 1999 Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof. Thomas R Adams, Sheryl A. Chambers, Richard J. Daines, William J. Gordon-Kamm, Albert P. Kausch, Peggy G. Lemaux, Catherine J. Mackey, Mary L. Mangano, James V. O’Brien, Thomas B. Rice, T. Michael Spencer, William G. Start, Nancy G. Willetts. Assignee: DEKALB Plant Genetics (Issued: October 19, 1999).USAPatent Office. Patent Number  5,969,213.

 

14. 2000 Chimaeric gene coding for a transit peptide and a heterologous polypeptide. L. Herrera‑Estrella, G. Van den Broeck, M. Van Montague, P. Schreier, J. Schell. H.J. Bohnert, A.R. Cashmore, M. Timko, A.P. Kausch, Assignees : Plant Genetic Sciences (PGS),GhentBelgium; and, Bayer A.G.Leverkusen.  (IssuedMay 16, 2000)USAPatent Office. Number 6,063,601.

 

15. 2000 Methods and compositions for transformation of Rhododendron spp. by microprojectile bombardment. M. Brand. C. Auer. J. Knapp, and Albert Kausch. Assignee:University of ConnecticutUSAPatent Office (Application).

 

16. 2000 Chimaeric gene coding for a transit peptide and a heterologous polypeptide. L. Herrera‑Estrella, G. Van den Broeck, M. Van Montague, P. Schreier, J. Schell. H.J. Bohnert, A.R. Cashmore, M. Timko, A.P. Kausch, Assignees : Plant Genetic Sciences (PGS),GhentBelgium; and, Bayer A.G.Leverkusen.  (IssuedOctober 10, 2000)USAPatent Office. Number 6,130366.

 

17. 2000 A Method for Transformation of Alfalfa. Anthony, J., Vlahova, M., Atanas,  A. and Kausch, Assignee:  HybriGene L.L.C.USAPatent Office (Application).

 

18. 2000  Maize chloroplast aldolase promoter compositions and methods for use thereof.” N. Houmard, L. B. Laccetti, E M. Orozco, and A.P. Kausch Assignee: DEKALB Plant Genetics US Patent Application No, 09/757,089USA

 

19. 2000 Method for reduction of transgene copy number Brenda Lowe, Michael Spencer and Albert P. Kausch. Assignee:  DEKALB Plant Genetics. (IssuedNovember 28, 2000)USAPatent Office. Number 6,153,811

 

20. 2001 Transgenic monocot plants with increased glycine betaine content. . T. R. Adams, P. C. Anderson, R. J. Daines, W. Gordon-Kamm, A. P. Kausch, M. T. Mann, P. M. Orr, D. C. Warner.  Assignee: DEKALB Plant GeneticsUS(IssuedAugust 28, 2001)USAPatent Office. Number 6,281,411

 

21.  2001 Site-specific recombination in turfgrass species .  Luo, H. and A Kausch.

Assignee:  HybriGene L.L.C.USAPatent Office (PCT Application).

 

22. 2002 Process of producing male sterile transgenic grasses and cereals, and their progeny. Luo, H.and Kausch. Assignee:  HybriGene L.L.C.USAPatent Office (PCT Application).

 

23.  2002 Methods and compositions for the production of stably transformed, male sterile monocot plants and cells thereof. Luo, H. and A Kausch. Assignee:  HybriGene L.L.C.USAPatent Office (Application).

 

24. 2002 Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof.  Anderson, Paul C.; Flick, Christopher E.; Gordon-Kamm, William J.; Kausch, Albert P.; Mackey, Catherine J.; Orozco, Emil M.; Orr, Peter; Stephens, Michael A.;; Walters, David A.; Walters, Donald S. Assignee: DEKALB Plant Genetics US (Issued ) USA Patent Office. Number Assignee: DEKALB Plant GeneticsUS(Issued June 4, 2002)USAPatent Office. Number 6,399,861

 

25.  2003 The use of total vegetative growth for prevention of transgene escape in genetically modified perennials. Luo, Hong., Melvin Oliver,Joel Chandleeand Albert  Kausch.USAPatent OfficeFebruary 7 2003(PCT Application).

 

26. 2003 Methods and compositions for the increase of yield in plants. Spencer, T. Michael; Adams, Thomas R.; Daines, Richard J.) ; Gordon-Kamm, William J ; Kausch, Albert P.; Lemaux, Peggy G. MacKey, Catherine J.; Mangano, Mary L.; Rice, Thomas B.  United States Patent Application Number 20030126634

 

27. 2004 Methods and Compositions for the Large Scale Production of Fresh Green Garlic. A Kausch Provisional Application

 

28. 2004. Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof Anderson; Paul C. Flick; Christopher E. Gordon-Kamm; William J. Kausch; Albert P. Mackey; Catherine J., Orozco; Emil M. Orr; Peter Stephens; Michael A. Walters; David A. Walters; Donald S.USA Patent Office 6,803,499

 

29. 2005 Green Garlic and Methods of Production.  A. Kausch andPeter SellewUSA Patent Office May 5 2005 (PCT Application Number 60/568,354, pending).

 

30. 2006 Methods and Compositions for Increasing Biomass in Genetically Modified Perennials Used for Biofuels. A. Kausch and M. Oliver.  January 23, 2007 Provisional Application

 

31. 2006 Maize chloroplast aldolase promoter compositions and methods for use thereof.” N. Houmard, L. B. Laccetti, E M. Orozco, and A.P. Kausch Assignee: DEKALB Plant Genetics US Patent Application No, 09/757,089 Assignee: Monsanto Corporation   Patent No. 7,151,204 USA

 

32. Kausch, A.P., and P. Sellew 2011 Green Garlic and Methods of Production. US Patent Number 7,937,889, Issued May 10 2011

 

33. Kausch, A.P. and P. Simon 2007 Methods and Compositions for the Large scale commercial production of green garlic and methods of production. Albert Kausch and Phillip Simon, Inventors U.S. PCT No. 60/568,354, filed May 5, 2007

 

34. Kausch, A.P.  and P. Simon 2007 Chemoprotective food products from fresh green garlic active against human food-bourne pathogens. Albert Kausch and Phillip Simon, Inventors U.S. PCT No. 60/568,355, filed May 5, 2007

35. 2009. Development of controlled total vegetative growth for prevention of transgene escape from genetically modified plants and for enhancing biomass production. Luo; Hong; Chandlee; Joel M.;Kausch; Albert P.; Oliver; Melvin J. United States Patent Application Number 20100122366

 

36. 2009. Male and female sterility lines used to make hybrids in genetically modified plants. Inventors: Albert Kausch and Stephen Dellaporta.  United States Patent Application. Assignee; University of Rhode Island

 

37.  2010. Prevention of transgene escape in genetically modified perennial plants. Luo; Hong; Hu; Qian; Vasilchik; Kimberly Nelson; Longo, JR.; John P.; Kausch; Albert P.; Zilinskas; Barbara; Lakkaraju; Subha Continuation in Part United States Patent  Application Number 20100031387  Filed February 4, 2010

 

38. 2010. Methods and compositions for the production of stably transformed, fertile monocot plants and cells thereof Adams; Thomas R. Anderson; Paul C. Chambers; Sheryl A. Chomet; Paul S. Daines; Richard J., Flick; Christopher E., Glassman; Kimberly Gordon-Kamm; William J., Kausch; Albert P., Laccetti; Lucille B., Lemaux; Peggy G., Mackey; Catherine J., Mangano; Mary Lou, Mann; Michael T. O’Brien; James V. , Orozco; Emil M. ,Orr; Peter , Rice; Thomas B. Spencer; T. Michael, Start; William G., Stephens; Michael A., Vetsch; Clayton S. Walters; David A. Walters; Donald S. Willetts; Nancy G., Zachwieja; Susan J., Assignee: Dekalb Genetics Corporation (Dekalb, IL) Appl. No.: 08/113,561   Filed August 25, 1993  US patent number 7,705,215

39.  2012  The use of genetically modified plants for recovery of non-genetically modified hybrids from wide crosses  Inventors: Adam Deresienski; Kimberly Nelson; Michael Tilleli; Joel Hague, Stephen Dellaporta  and Albert Kausch. United States Patent Application. Assignee; University of Rhode Island

 

40. 2012.  In situ embryo rescue and recovery of non-genetically modified hybrids from wide crosses Inventors: Kimberly Nelson; Adam Deresienski; Michael Tilleli; Joel Hague and Albert Kausch. United States Patent Application. Assignee; University of Rhode Island

 

‡ the listed patent applications are in various stages of issuance; thirteen (13) are issued US patents, one (1) is an issued European patent,  four (4) are PCT applications, four (4) are provisional applications, and two (2) are responding to review.

 

*Because of signed confidentiality agreements, I am not permitted to provide exact titles, disclose filing dates and other designations to some of these documents.

 

F.  Selected recent invited and guest speaker titles (last 4 years only)

 

  1. A. Kausch, J. Hague, L. Perretta and K. Nelson (2013) Agricultural Biotechnology: A Massive Open Online Course (MOOC) Module Covering    in Simple Terms Basic Knowledge About DNA and Plant Biotechnology.  Plant Biology 2013, Annual Meetings of the American Society of Plant Biologists, July 20-24, Providence, Rhode Island, USA.
  2. J. Hague, M. Tilelli, D. Cunha, K. Nelson and A. Kausch (2013) In Situ Embryo Rescue as a Novel Method for Recovery of Non-GMO Hybrids from Wide Crosses. Plant Biology 2013, Annual Meetings of the American Society of Plant Biologists, July 20-24, Providence, Rhode Island, USA.
  3. Kausch, Albert. Invited Speaker. (2012) The use of synthetic male and female sterility for recovery of Non-Genetically Modified Hybrids from Wide Crosses. Department of Horticultural Science, North Carolina State University, Mountain Horticultural Crops Research and Extension Center, October 19, 2012
  4.  Kausch, Albert (2012) Invited Speaker.  Bioenergy: Genetic Improvement of Bioenergy Crops for Biofuels and Prospects for Artificial Photosynthesis. Department of Chemistry.  Brown University, Providence Rhode Island. September 14, 2012
  5. Kausch, Albert (2012) Invited Speaker.  Bioenergy: Genetic Improvement of Bioenergy Crops for Biofuels Department of Botany connecticut College, new London CT. September 21, 2012
  6. .A. Kausch, A. Deresienski, J. Hague, M.Tilelli, K. Nelson (2012) Issues in Biotechnology: An Online General Education Undergraduate Course Covering Simple Terms Basic Knowledge About DNA and Biotechnology. Plant Biology 2012, Annual Meetings of the American Society of Plant Biologists, July 20-24, Austin, TX, USA.
  7. J. Hague, A. Deresienski, M.Tilelli, K. Nelson, A. Kausch (2012) The Analysis of Expression Characteristics of the Maize Pollen Specific Promoter MPSP Zm13 And A Strategy for Gene Confinement in Transgenic Bioenergy Crops. Plant Biology 2012, Annual Meetings of the American Society of Plant Biologists, July 20-24, Austin, TX, USA.
  8. A. Deresienski, K. Nelson, M.Tilelli, J. Hague, A. Kausch (2012) Use of a Herbicide Resistance Selectable Marker for Recovery of Intraspecific and Interspecific Hybrids in Switchgrass. Plant Biology 2012, Annual Meetings of the American Society of Plant Biologists, July 20-24, Austin, TX, USA.
  9. K. Nelson, A. Deresienski, M.Tilelli, J. Hague, A. Kausch (2012) A Project-based Undergraduate Internship Program in Agricultural Biotechnology. Plant Biology 2012, Annual Meetings of the American Society of Plant Biologists, July 20-24, Austin, TX, USA.
  10. M.Tilelli, K. Nelson, A. Deresienski, J. Hague, A. Kausch (2012) Use of a Selectable Marker for In Situ Embryo Rescue using Transgenic Switchgrass for Recovery of Wide Crosses. Plant Biology 2012, Annual Meetings of the American Society of Plant Biologists, July 20-24, Austin, TX, USA.
  11. A. Deresienski, K. Nelson, J. Hague, A.P. Kausch (2009) Male sterility as a method for constructing wide crosses and for gene confinement in switchgrass and other biofuels grasses.  Plant Biology 2009, Annual Meetings of the American Society of Plant Biologists, July 18-22, Hawaii, USA.
  12.  K. Nelson, J. Hague, A. Deresienski and A.P.Kausch.  (2009) Improved methods for tissue culture and genetic transformation of switchgrass.  Plant Biology 2009, Annual Meetings of the American Society of Plant Biologists, July 18-22, Hawaii, USA.
  13. Transgenic biofuel feedstocks from perennial plants: requirements and strategies for biocontainment

Albert P. KauschPlant Biotechnology seminar seriesUniversityofMassachusetts,AmherstMASept 22, 2009

  1. Improved methods for tissue culture and genetic transformation of switchgrass A.KAUSCH, K. Nelson, J. Hague, and A. Deresienski, Plant Biotechnology Laboratory,  Department of Cell and Molecular Biology, University of Rhode Island, West Kingston RI  02892 Amer. Soc. Plant Biology July 22-26 2009.
  2. Strategies for Gene Confinement in Genetically Modified Perennial Plants Used for Biofuels

A.P. KAUSCH, J. Hague, A. Deresienski, K. Nelson, and Melvin Oliver. Plant Biotechnology Laboratory,  Department of Cell and Molecular Biology,UniversityofRhode Island,West KingstonRI 02892Soc. In Vitro BiologyJune 6-9 2009

 

 

 

G. Educational Materials ( Lectures, YouTube, Online Courses, DVDs, Workshops, etc.)

 

  1. lifeedu.us Issues in Biotechnology: Meeting the Current Educational Crisis on Biotechnology.  A  General OnLine Course.2013. (YouTube Lecture Series and Course Materials) Albert P. Kausch.

 

  1. lifeedu.us Agricultural Biotechnology: Informing the Debate A  General Massive Open OnLine Course (MOOC).2013. (Workshop; YouTube Lecture Series and Course Materials) Albert P. Kausch.

 

  1. lifeedu.us Pharmaceutical Biotechnology: The Future is Now. A  General Massive Open OnLine Course (MOOC). 2013. (Workshop, YouTube Lecture Series and Course Materials) Albert P. Kausch.

 

  1. Kausch, AP, Hague, J, Deresienski A, Tilelli M,  Longo C, and Nelson, K (2012) Issues in Biotechnology: A Massive Open Online Course (MOOC) Covering in Simple Terms Basic Knowledge About DNA and Biotechnology

 

  1. Issues in Biotechnology: A General Course on Biotechnology. (Course Materials) 2011. Albert P. Kausch

 

  1. The Way We Work With Life: Issues in Biotechnology. 2009-2012 A lecture series On the Principles, Applications, & Ethics of Biotechnology   (containing nineteen lectures contributed by several co-authors)  Albert P. Kausch, Editor.

 

  1. An Educational Workshop for Investment Professionals: The Introduction of Concepts and Applications Regarding DNA, Biotechnology, and the Life Sciences Industries. 2002. (A DVD and Workbook package produced and delivered to Connecticut Innovations, Inc. and the Connecticut Department of Economic and Community Development (DECD) May 18 2012) Albert P. Kausch

 

  1. A Workshop for High School Teachers on the General Principles and Applications of Biotechnology. 2009 (A CD & Workbook package produced in collaboration with Pfizer, Inc.) Albert P. Kausch

 

  1. Agricultural Biotechnology: A teaching module for fifth and sixth grade. 2002Albert Kauschand Chip Longo.

 

  1. The Way We Work With Life: Issues in Biotechnology. 2002 A Lecture Series On the Principles, Applications, & Ethics of Biotechnology (CD containing twenty three lectures contributed by over fifteen renowned authors, Presented atConnecticutCollege, Sponsored by Pfizer, Inc,) Albert P. Kausch, Editor.

 

  1. A Workshop for High School Teachers on an Educational Kit for Instructional Use on Agricultural Biotechnology 2003. (A CD & Workbook package including materials for learning oriented activities produced in collaboration with Pfizer, Inc.) Albert P. Kausch andChip Longo.

 

  1. A One Day Survey Workshop for Science and Non-Science Staff in the Biopharmaceutical Industries on the Principles and Applications of Biotechnology. 2003. (A CD and Workbook package designed and produced for the Science and Non-science Staff of AMGEN.) Albert P. Kausch

 

  1. The Way We Work With Life: Issues in Biotechnology. 2003 A Lecture Series On the Principles, Applications, & Ethics of Biotechnology (CD containing twenty three lectures contributed by over fifteen renowned authors, Presented atConnecticutCollege, Sponsored by Pfizer, Inc,) Albert P. Kausch, Editor.

 

  1. A One Week Workshop for High School Teachers On Agricultural Biotechnology Albert P. Kausch andChip Longo. June 2003albertP. Kausch

 

  1. A One Day Survey Workshop for High School Teachers. 2004. All Matters Biotechnology. (A CD and Workbook package designed and produced with the Science and Non-science Staff of AMGEN.) Albert P. Kausch

 

  1. Plant Biotechnology for the Developing World. 2004. Albert P. Kausch

 

  1. The Way We Work With Life: A Thirty DVD set from the Issues in Biotechnology course series. 2005

 

  1. A Workshop on Gene Confinement for Genetically Modified Grasses. (Organizer) May 14, 2005

 

 

H.  List of Expert Witness Testimony at Trial or by Deposition.

 

  1. DeKalb Genetics Corporation v. Pioneer Hi-Bred International, Mycogen Corporation, CIBA-Geigy and Northrup KingNovember 5-10, 1997

 

  1. DeKalb Genetics Corporation v. Pioneer Hi-Bred International, Mycogen Corporation, CIBA-Geigy and Northrup KingJanuary 17, 1998

 

  1. DeKalb Genetics Corporation v. Pioneer Hi-Bred International, Mycogen Corporation, CIBA-Geigy and Northrup KingFebruary 21, 1998

 

  1. DeKalb Genetics Corporation v. Pioneer Hi-Bred International, Mycogen Corporation, CIBA-Geigy and Northrup KingMay 9, 1998

 

  1. DeKalb Genetics Corporation v. Pioneer Hi-Bred InternationalJune 18, 1998

 

  1. ABT Intellectual Property Trial,Las Vegas,Nevada,  July 22, 2003

 

I. Other Creative Works

 

1. The Continuum. Poetry by Albert Kausch 1991 Hozomeen Press NYC New York

 

2. A Thousand Luna Moths. Poetry by Albert Kausch 1992 Hozomeen Press NYC New York

 

3. The Autarkic. Poetry by Albert Kausch 1993 Hozomeen Press NYC New York

 

4. Hozomeen Jam; A Compilation of Spoken Poems with music by David Amram 2001 NYC New York

 

5. The Abandon. A novel by Albert Kausch 2007 (unpublished)

 

6. The Abandon. A Play for Voices adapted by Ruth Rosen from the novel by Albert Kausch 2010

Performed at The Kips Bay Library, NYCFebruary 20, 2010and The LaGruaCenter,Stonington,CTJune 19, 2010.

 

7. The Book of Fighting.  A Children’s Book. Albert Kausch and Nelson Vasilchik. Watch Hill Press CT 2011

 

8. The Book of Ing.  A Children’s Book. Albert Kausch and Nelson Vasilchik. Watch Hill Press CT 2011

 

References

 

Dr. Thomas Hodges                                        Dr. Stephen Dellaporta

J.C. Arthur Distinguished Professor                Professor

PurdueUniversity,                                          YaleUniversity

West Lafayette,IN47907                               New Haven,CT

tkhodges@purdue.edu                                     stephen.dellaporta@yale.edu

Tele 410-745-9505                                          Tele 203-432-3895

 

 

Dr. Joel Chandlee                                          

Professor

CELS CMB

UniversityofRhode Island

joel_chandlee@uri.edu

Tele 401-874- 2529