Methotrexate is a folate inhibitor that targets the dihydrofolate reductase (DHFR) enzyme, resulting in interference with nucleotide synthesis and cellular repair.  For this reason, methotrexate is used as an anti-cancer drug.  The goal of this app is to demonstrate the activity of methotrexate when interacting with DHFR in a virtual environment that requires the user […]

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