Detecting SOD1 Aggregates In A Drosophila Model Of Amyotrophic Lateral Scelerosis

INVESTIGATORS: Geoff Stilwell, Rhode Island College THEME: Neuroscience ABSTRACT: Amyotrophic Lateral Sclerosis (ALS) is characterized by progressive motor neuron (MN) degeneration, muscle weakness and death within 3-5 after diagnosis. Mutations in superoxide dismutase 1 (sod1) cause ALS and approximately 170 different mutations in this gene have been documented in patients to date. Irrespective of which […]

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Neuroscience: Negative Experiences and Late Adolescents Health Outcomes

INVESTIGATOR: Emily Cook, Rhode Island College THEME: Neuroscience ABSTRACT: Past research during adulthood has suggested that how individuals handle stress emotionally and physically has implications for behavioral and physical health during adolescence. Yet we know little about daily stressors (i.e., minor yet frequent stressful experiences such as daily tests, family arguments) among late adolescents (the […]

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Neuroscience: Disrupting Toxic Protein Aggregates in a Yeast Model of Parkinson’s Disease

INVESTIGATOR: Nicanor Austriaco, Providence College THEME: Neuroscience ABSTRACT: Parkinson’s Disease (PD) is a neurodegenerative disorder that leads to progressive deterioration of motor function due to the loss of dopamine-producing cells in the brain. The pathological hallmark of PD is the abnormal aggregation of specific proteins, including, most significantly, α-synuclein, which is an abundant, presynaptic protein of […]

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