RI-INBRE Workforce Development Training (WDT) Summer 2023 Syllabus
Module Title: Patient Simulation and Drug Effects
Instructor: Clinton Chichester, Ph.D., Amanda Chichester, M.S. and John Donahue, B.S.
This WDT Module will train students in the basics of disease state modeling and the programming of drug effects in simulated patients. The module is intended for students with limited clinical backgrounds to experience a simulated clinical experience. Students will participate in several simulated clinical experiences and then will be given the opportunity to develop as part of a group to develop their own simulated patient(s). Students will do a literature review of the critical features of their disease state that they will be modelling. They will then develop their clinical case with all the required elements. This may include drug effects which may or may not have to be programmed. If a drug is to be included in the module to be developed lectures on modelling of drug effects will be provided. This module is intended for students new to clinical research data generation and analysis. It will provide sufficient background for students to gain understanding of the pathophysiology principles involved in their modeled disease state. It will allow those students to pursue further training in these and related research areas. The module will be completed over 2.5 days and participants who complete the module will receive an RI-INBRE Certificate of Completion.
- Gain a sufficient understanding of basic pathophysiology principles and terminology.
- Prepare a clinical scenario that accurately reflects a real disease situation.
- Learn methodology to accurately model drug effects- both pharmacodynamics and pharmacokinetics.
- Process disease state data from the literature search and tabulate the data for future use.
Students will be expected to prepare a detailed case study with associated background material:
- Library analysis protocols.
- Data analysis protocols (e.g., workflows, software used, etc.)
- Quality control metrics.
Resources Used in this Module:
- CVS Health Interdisciplinary Health Delivery Simulation Laboratory
- Standard Operating Procedures – Notes prepared for teaching simulations in the College of Pharmacy
- Slide Decks for Lecture
|Day 1||Day 2||Day 3|
|9:00 AM-10:00 AM||Introduction to Human Patient Simulation||Participation in a simulated case study (#2)||Preparing the final description of the case|
|10:00 AM-11:00 AM||Participation in a simulated case study (#1)||Discussion and continued development the simulated disease state||Programming the case in the simulator
|11:00 AM-12:00 PM||Discussion about clinical disease states that are of interest and the critical elements needed to develop a clinical scenario||Demonstration of simulated drug effects in the lab- both primary effects and reflexes||Class demonstration of the case developed and discussion|
|12:00 - 1:00 PM||Break||Break||Closing Group Lunch|
|1:00 PM-2:00 PM||Research of clinical disease state||Preliminary outline of case elements|
|2:00 PM-3:00 PM||Modelling of drug effects- Pharmacodynamics and Pharmacokinetics (lecture)||Continued research on case|
|3:00 PM-4:00 PM||Continued refinement of topic||Continue research|