Impacts of maternal PFOS exposure on neuronal development

Investigator: Belinda Barbagallo, Salve Regina University Theme: Neuroscience Title: Impacts of maternal PFOS exposure on neuronal development  Award: SURF PUI Training Award (2022-2024) Abstract: Neurodevelopmental disorders, including autism, attention-deficit/hyperactivity disorder (ADHD) and learning disabilities, affect approximately 15% of children in the United States, with the prevalence of multiple disorders rising over the last four decades. Most […]

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Exploring the Relationship between Structure and Function in KmtR

Investigator: Khadine Higgins, Salve Regina University Theme: Environmental Health Sciences Title: Exploring the Relationship between Structure and Function in KmtR Award: SURF PUI Training Award (2022-2024) Abstract: The long-term goal of this work is aimed at understanding why Mycobaterium tuberculosis (M. tuberculosis) requires two Ni(II)- and Co(II)-responsive metalloregulators associated with the export of Ni(II) and […]

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Analyzing the mechanisms of unique adherence phenotypes of super shedder E. coli

Investigator: Matthew Moreau, Salve Regina University Theme: Environmental Health Sciences Title: Analyzing the mechanisms of unique adherence phenotypes of super shedder E. coli  Award: SURF PUI Training Award (2022-2024) Abstract: Super shedding (SS) of Shiga-toxin producing Escherichia coli (STEC) from its cattle reservoir is responsible for producing most of the environmental burden of this bacterium. […]

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Method and device for electrochemical detection of Thiocyanate ions in saliva

Investigator: Clifford Murphy, Roger Williams University Theme: Cancer Title: Method and device for electrochemical detection of Thiocyanate ions in saliva  Award: SURF PUI Training Award (2022-2024) Abstract: This project with adapt an existing invention for the detection of thiocyanate ions in seawater to the analysis of thiocyanate concentrations in human saliva for application as a […]

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Genetic analysis of Kita signaling during melanocyte migration

Investigator: Larissa Patterson, Rhode Island College Theme: Cancer Title: Genetic analysis of Kita signaling during melanocyte migration Award: SURF PUI Training Award (2022-2024) Abstract: The KIT receptor tyrosine kinase is required for many aspects of melanocyte behavior including melanogenesis, proliferation, migration, and survival. Mutations resulting in constitutive activation of KIT promote the formation and progression […]

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Impact of flagellin methylation on plant immune responses against human pathogens

Investigator: Anne Reid, Salve Regina University Theme: Environmental Health Sciences Title: Impact of flagellin methylation on plant immune responses against human pathogens Award: SURF PUI Training Award (2022-2024) Abstract: Over 1 million cases of salmonellosis occur annually in the US, with outbreaks increasingly linked to fresh fruits and vegetables. Bacterial flagella mediate swimming motility as well […]

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Characterizing differences in tissue specific mitochondrial function for neurodegenerative disease

Investigator: Geoff Stilwell, Rhode Island College Theme: Neuroscience Title: Characterizing differences in tissue-specific mitochondrial function for neurodegenerative disease Award: SURF PUI Training Award (2022-2024) Abstract: Mitochondrial function is disrupted at early stages in neurodegenerative disease and this dysregulation contributes to fundamental changes that are part of the disease state in metabolism, innate immune responses, energy […]

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Top-down and bottom-up processing in the posterior parietal cortex

Investigator: Victoria Templer, Providence College Theme: Neuroscience Title: Top-down and bottom-up processing in the posterior parietal cortex Award: SURF PUI Training Award (2022-2024) Abstract: The purpose of this project is to determine the functional contribution of the rat posterior parietal cortex (PPC) to specific forms of information processing. The PPC has been generally shown to […]

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Metabolic dysregulation in Frontotemporal Dementia

Investigator: Marla Tipping, Providence College Theme: Neuroscience Title: Metabolic dysregulation in Frontotemporal Dementia Award: SURF PUI Training Award (2022-2024) Abstract: A common attribute of neurodegenerative disease is a change in the way cells break down and utilize nutrients, as well as their ability to build new macromolecules. Collectively, this is referred to as metabolic reprogramming, […]

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