Investigator Focus Jyothi U, Menon, PhD – Cancer Moonshot Scholar Dr. Jyothi U. Menon has the prestigious honor of being one of eleven researchers selected to the inaugural cohort of the Biden Cancer Moonshot Scholars program! The National Institutes of Health 5-year (2023-2028) R01/R37 award, from the National Cancer Institute is entitled “Multifunctional Nanoparticle Platform to […]
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A computational approach to the study of malate dehydrogenase
Co-Investigator: Kathleen Cornely, Providence College Co-Investigator: Tyler Stack, Providence College Scientific Theme: Cancer Abstract: There are several benefits to replacing traditional labs with Course-based Undergraduate Research Experiences (CUREs). Providing research experience to all students improves motivation, engagement with their classmates and professors, and persistence in STEM. Like any CURE, our current CHM 310 class aims […]
Continue reading "A computational approach to the study of malate dehydrogenase"Methotrexate VR
Methotrexate is a folate inhibitor that targets the dihydrofolate reductase (DHFR) enzyme, resulting in interference with nucleotide synthesis and cellular repair. For this reason, methotrexate is used as an anti-cancer drug. The goal of this app is to demonstrate the activity of methotrexate when interacting with DHFR in a virtual environment that requires the user […]
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INVESTIGATOR: Jamie Towle-Weicksel, Rhode Island College COLLABORATIVE MENTOR: Sarah Delaney, Brown University THEME: Cancer ABSTRACT: Skin exposed to UV light is one of the major contributing factors for developing melanoma. It is hypothesized that cancer begins at the DNA level through genomic instability as UV light distorts the DNA bases and disrupts DNA replication and transcription. This […]
Continue reading "A Link to Melanoma: Discovering the Role of Pol Theta in UV Damage Repair"Use of Targeted Nanometer-Size Materials to Increase the Effectiveness of Radiation on Cancer
Investigator: Michael Antosh, University of Rhode Island Scientific Theme: Cancer Abstract: The broad objective of this project is to improve the treatment of cancer by enhancing the effect of radiation on cancer. If radiation can be made to have a greater impact on cancer, less radiation can be used, which would reduce side effects to patients. Alternatively, more […]
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