We have been developing and applying modeling methods to simulate the growth of microorganisms under different environmental conditions. Using a method called Thermodynamics-Based Metabolic Flux Analysis, we are able to incorporate temperature, thermodynamic feasibility of reactions, and metabolite concentrations into simulations of bacterial growth. Our goal is to further develop these methods so that they can be more broadly applied to key organisms in the Narragansett Bay ecosystem.
RI NSF EPSCoR is supported in part by the U.S. National Science Foundation under EPSCoR Cooperative Agreements #OIA-2433276 and in part by the RI Commerce Corporation via the Science and Technology Advisory Committee [STAC]. Any opinions, findings, conclusions, or recommendations expressed in this material are those of the author(s) and do not necessarily reflect the views of the U.S. National Science Foundation, the RI Commerce Corporation, STAC, our partners or our collaborators.