Hu, Xindi C., Clifton Dassuncao,Xianming Zhang, Philippe Grandjean, Pál Weihe, Glenys M. Webster, Flemming Nielsen, and Elsie M. Sunderland. “Can profiles of poly-and Perfluoroalkyl substances (PFAS) in human serum provide information on major exposure sources? ” Environmental Health 17, no. 1 (2018): 11.
PFAS are a prevalent toxic chemical in the environment, which results in frequent human exposure through a multitude of sources. Analytical advancements have allowed for improved detection of PFAS in humans, which in turn allows for improved PFAS exposure profiling. However, PFAS composition varies among sources, which can have associated adverse health effects. This study assessed PFAS concentrations in several demographic groups’ serum samples to identify possible similarities in exposure sources. The study’s findings show that PFAS profiles in human serum provide important information, like a chemical fingerprint, on major exposure sources of the chemicals. This knowledge can then be used to attribute adverse health effects to certain mixtures or individual types of PFAS. View article