The 2022 STEEP Annual Report highlights persistent concerns regarding poly- and perfluoroalkyl substances (PFAS), emphasizing their adverse effects on the immune system and sensitive tissues, especially during early-life exposures. To address these concerns, a comprehensive birth cohort study was conducted in the Faroe Islands with support from the National Institute of Environmental Health Sciences (NIEHS). Leveraging the Faroese population’s homogeneity and diverse exposure range, the study followed nearly 3,000 PFAS-exposed children from birth, conducting clinical examinations including specialized assessments.
Simultaneously, efforts were made to enhance PFAS analytical methods using more sensitive systems. Data from clinical examinations, blood tests, and PFAS analyses were meticulously documented in a comprehensive database. Advanced statistical analyses aim to elucidate associations between PFAS exposure and vaccine antibodies, as well as metabolic biomarkers.
This multifaceted approach underscores STEEP’s dedication to advancing knowledge and addressing public health challenges posed by PFAS contamination. By combining clinical assessments with advanced analytical techniques, the initiative represents a significant stride in understanding PFAS health effects, particularly during crucial developmental stages.
