- Presented at ASHP Midyear 2013
- Danielle M. Ouellette, Pharm.D., Candidate, Alev H. Gulum, Pharm.D., Candidate,
Research
- Studies have shown that magnesium exerts beneficial effects on the cardiovascular system by enhancing endothelium-dependent vasodilation, improving lipid and glucose metabolism, reducing inflammation and inhibiting platelet aggregation
- Low serum and dietary magnesium intake are established risk factors for cardiac arrest, fatal coronary heart disease, stroke, insulin resistance, type 2 diabetes mellitus, hypertension, and sudden cardiac death
- African Americans have a high prevalence of heart failure and age-adjusted incidence of developing heart failure as compared to Hispanic, Caucasian and Chinese Americans
- African Americans in general have worse indices of diastolic dysfunction as compared to Caucasians
- A direct relationship between dietary magnesium intake and systolic or diastolic function parameters as measured by echocardiography has not been established