Relationship Between Dietary Magnesium Intake and Incident Heart Failure in African American Adults

  • Presented at ASHP Midyear 2013
  • Alev H. Gulum, Pharm.D., Candidate, Danielle M. Ouellette, Pharm.D. Candidate

Research

  • In 2013,  over five million individuals in the United States (US) over the age of 20 have been diagnosed with heart failure (HF)
  • The prevalence of HF is projected to increase 25% by 2030 and the cost of hospitalizations due to HF will increase 120% to nearly 70 billion dollars. Survival has improved over time with advancements in medical care; however the 5-year survival rate of patients after diagnosis is only 50%.
  • African Americans have the highest HF prevalence and age-adjusted incidence of developing HF compared with Hispanic, Caucasian, and Chinese Americans.
  • Low serum and dietary magnesium intake are established risk factors for cardiac arrest, fatal coronary heart disease, stroke, insulin resistance, type 2 diabetes mellitus, hypertension, and sudden cardiac death.
  • An inverse association has been established with magnesium intake and these risk factors for HF such as hypertension, diabetes, and dyslipidemia; however, little is known regarding the relationship