Clinton Chichester III, Ph.D.

Clinton Chichester III, Ph.D. Professor
  • Professor
  • Office: 395B Lab: 470
  • Phone: 401.874.5034
  • Email: chichester@uri.edu
  • Office Location: Avedisian Hall, 7 Greenhouse Road, Kingston, RI 02881

Biography

Dr. Chichester’s teaching and research interests are in pharmacology and in connective tissue metabolism. In addition Dr. Chichester is the Co-Director of the Patient Simulation Laboratory and Director of the cGMP Facility.

Research

Connective tissue pharmacology; Collagen degradation in osteoarthritis; Alterations in drug metabolism in septic shock

Education

Ph.D. in Pharmaceutical Sciences, University of Rhode Island, 1980
M.S. in Pharmacology and Toxicology, University of Rhode Island, 1977
B.S. in Biochemistry, University of California, 1973

Selected Publications

Mackay, A.M., Beck, S.C., Murphy, J.M., Barray, F.P., Chichester, C.O. and Pittenger, M.R. Chondrogenic Differentiation of Cultured Human Mesenchmal Stem Cell from Marrow. Tissue Engineering 4: 415-428, 1998

Felice, B.R., Chichester, C.O. and Barrach, H.-J. Type II Collagen Peptide Release from Rabbit Articular Cartilage. Ann. N.Y. Acad. Sci. 878: 590-593, 1999

McKindley, D.S., Chichester, C.O., Raymond, R. Effect of Endotoxin Shock on the Clearance of Lidocaine and Indocyanine Green in the Perfused Rat Liver. Shock. 12:468-472, 1999

Rogart, J.N., Barrach, H.-J., and Chichester, C.O. Articular Cartilage Degradation in the Hulty-Telhag Model of Osteoarthristis. Osteoarthritis and Cartilage. 7:539-547, 1999

McKindley, D.S., Boulet, J., Sachdeva, K., Wang, P., Chichester, C.O. Endotoxic shock alters the pharmacokinetics of lidocaine and monethylglycinexylidide. Shock. 17:199-204, 2002.

Jay GD, Elsaid KA, Zack J, Robinson K, Trespalacois F, Cha CJ, Chichester CO. Lack of chondroprotection occurs among emergency department patients with knee joint synovitis. J Rheum 31:557-564, 2004.

Chichester C. O, Felice B. R. Simulations in Pharmacology, in Practical Health Care Simulations, p. 143- 158, Loyd G. E., Lake C. L., Greenberg R. B. eds. Elsevier Mosby 2004.

Ma Y, Sachdeva K, Liu J, Ford M, Yang D, Khan IA, Chichester CO, and Yan B. Desmethoxyyangonin and dihydromethysticin are two major pharmacological kavalactones with potent activity on the induction of cytochrome P4503A23. Drug Metabolism and Disposition 32:1317-1324,2004.