- Research Assistant Professor & RI-INBRE Research Core Facility Director
- Office: 405 Lab: 405
- Phone: 401.874.5731
- Email: angcai@uri.edu
- Office Location: Avedisian Hall, 7 Greenhouse Road, Kingston, RI 02881
Research
Drug-protein interactions, DNA modification and protein glycation
Education
Postdoctoral Fellow, The University of Rhode Island, USA
Ph.D., Pharmaceutical Science, The University of Rhode Island, USA
M.S., Pharmaceutical Engineering, New Jersey Institute of Technology, USA
B.S., Pharmacognosy, Beijing University of Chinese Medicine, China
Selected Publications
Li, H.; Xu, F.; Liu, C.; Cai, A.; Dain, J. A.; Li, D.; Seeram, N. P.; Cho, B. P.; Ma, H., Inhibitory Effects and Surface Plasmon Resonance-Based Binding Affinities of Dietary Hydrolyzable Tannins and Their Gut Microbial Metabolites on SARS-CoV-2 Main Protease. J Agric Food Chem 2021, 69 (41), 12197-12208.
Cai, A.; Bian, K.; Chen, F.; Tang, Q.; Carley, R.; Li, D.; Cho, B. P., Probing the Effect of Bulky Lesion-Induced Replication Fork Conformational Heterogeneity Using 4-Aminobiphenyl-Modified DNA. Molecules 2019, 24 (8).
Liu, W.; Cai, A.; Carley, R.; Rocchio, R.; Petrovas, Z.; Chartier, C.; Meng, X.; Su, J.; Cho, B.; Dain, J.; Ma, H.; Seeram, N., Bioactive anthraquinones found in plant foods interact with human serum albumin and inhibit the formation of advanced glycation endproducts. Journal of Food Bioactives 2018, 4.
Cai, A.; Wilson, K. A.; Patnaik, S.; Wetmore, S. D.; Cho, B. P., DNA base sequence effects on bulky lesion-induced conformational heterogeneity during DNA replication. Nucleic Acids Res 2018, 46 (12), 6356-6370.
Tang, Q.; Cai, A.; Bian, K.; Chen, F.; Delaney, J. C.; Adusumalli, S.; Bach, A. C., 2nd; Akhlaghi, F.; Cho, B. P.; Li, D., Characterization of Byproducts from Chemical Syntheses of Oligonucleotides Containing 1-Methyladenine and 3-Methylcytosine. ACS Omega 2017, 2 (11), 8205-8212.
Liu, W.; Wei, Z.; Ma, H.; Cai, A.; Liu, Y.; Sun, J.; DaSilva, N. A.; Johnson, S. L.; Kirschenbaum, L. J.; Cho, B. P.; Dain, J. A.; Rowley, D. C.; Shaikh, Z. A.; Seeram, N. P., Anti-glycation and anti-oxidative effects of a phenolic-enriched maple syrup extract and its protective effects on normal human colon cells. Food Funct 2017, 8 (2), 757-766.
Giulietti, J. M.; Tate, P. M.; Cai, A.; Cho, B.; Mulcahy, S. P., DNA-binding studies of the natural beta-carboline eudistomin U. Bioorg Med Chem Lett 2016, 26 (19), 4705-4708.
Ma, H.; Wang, L.; Niesen, D. B.; Cai, A.; Cho, B. P.; Tan, W.; Gu, Q.; Xu, J.; Seeram, N. P., Structure Activity Related, Mechanistic, and Modeling Studies of Gallotannins containing a Glucitol-Core and alpha-Glucosidase. RSC Adv 2015, 5 (130), 107904-107915.