URI Pharmacy professor, students to battle Meningitis B

Pharmacy Professor Virginia Lemay, seen here administering a flu shot last year, will head up a meningitis B vaccination clinic and information campaign.

Grant to fund vaccination clinic, education campaign on potentially deadly illness The ­University of Rhode Island College of Pharmacy will address a serious health concern on college campuses while preparing future pharmacists to help contain a bacterial outbreak, thanks to a grant to expand its “Operation Immunization” program to tackle Meningitis B. The program recently […]

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Arylamine DNA adduct recognition in eukaryotic nucleotide excision repair (NIH/NIEHS 5R21 ES028384) in collaboration with Dr. Jung Hyun Min at Baylor University

Aromatic amines are among the most notorious environmental chemicals. At pathologically relevant concentrations, their reactive metabolites can react with cellular DNA to produce bulky lesions. If not efficiently repaired, these lesions can result in mutations that lead to various sporadic cancers. Understanding the mechanisms by which these lesions are recognized by the XPC nucleotide excision […]

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Mutational spectra of bulky DNA lesions (NIEHS 5R01ES028865) in collaboration with Dr. Deyu Li (PI) at The University of Rhode Island

Many aromatic amines are environmental toxins and human carcinogens. They damage genome and form different bulky DNA lesions, which give rise to different mutation patterns. This application will study the mutational spectra of bulky DNA lesions generated from aromatic amine exposure and provide insights into the development of tumors. Project Summary Many environmental toxins damage […]

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Protein binding of per- and polyfluoroalkyl substances (PFASs) as part of URI/Harvard Superfund STEEP (NIH/NIEHS 3P42ES027706)

Per- and polyfluoroalkyl substances (PFASs) are used to make surfaces water and oil resistant and can be found in cookware and fabric, as well as firefighting foam. They are ubiquitous and are contaminating water supplies near manufacturing plants and fire training sites.  PFASs are present in blood serum of 99% of human population worldwide. To […]

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