Comparative Effectiveness Research (CER): Where to Begin? A Literature Review of CER Methods Guides

  • Robert O McConeghy, BA(1), Nicolle M Gatto, PhD, MPH(2,3) and Aisling R Caffrey, PhD, MS(1,4)

Research

Background: Given the obstacles facing healthcare systems worldwide, an increased interest in CER has emerged as we seek to determine which treatments work best under real-world conditions. Currently, there is a lack of consensus regarding standardized approaches to the planning and conduct of CER. Formal methodological guidance can assist researchers in applying accepted and appropriate CER methods. However, it is unknown how many CER methods guides exist and the extent of agreement or differences between recommendations in these documents.
Related People: Aisling R. Caffrey
(1)College of Pharmacy, University of Rhode Island, Kingston, RI, United States
(2)Pfizer Inc, New York, NY, United States
(3)Department of Epidemiology, Columbia University, New York, NY, United States
(4)Infectious Diseases Research Program, Providence Veterans Affairs Medical Center, Providence, RI, United States