- Presented at American Pain Society Annual Meeting 2013
- Paige Houlihan,(1) Jayne Pawasauskas, PharmD, BCPS,(1,2) Rouba Youssef, MA,(3) and Michelle Kelley, PharmD,(2)
Research
- Intravenous acetaminophen was approved by the FDA in November 2010.
- Clinical trials have demonstrated many benefits of IV acetaminophen in the post operative orthopedic setting, and have compared the use of IV acetaminophen with both placebo and morphine for post-operative pain management.
• These studies found that the use of IV acetaminophen was associated with greater pain relief, less opioid use, increased patient satisfaction, and fewer drug related adverse events.(1,2)
• Significant reductions in opioid related adverse events of nausea, vomiting, and dizziness, have been seen in patients treated with IV acetaminophen.(2)
- The use of IV acetaminophen could reducstaye costs by reducing opioid needs, adverse events, time in the post-anesthesia care unit (PACU), and length of hospital.
Related People: Jayne Pawasauskas
(1) University of Rhode Island College of Pharmacy, Kingston, RI
(2) Kent Hospital Department of Pharmacy, Warwick, RI
(3) University of Rhode Island Department of Psychology , Kingston, RI
(3) University of Rhode Island Department of Psychology , Kingston, RI