Most commonly people take oral doses of a drug over an extended period. This model demonstrates the unique plasma concentration profile associated with this type of drug administration. The model assumes first-order drug absorption with no lag time. Simulations can be carried out to observe how the rate and extent of absorption (bioavailability) affect the profile.

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See Chapter 14: Multiple Oral Doses
Topics relevant to this model are covered in the following sections:

– 14.4 Simulation Exercise

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  Basic Pharmacokinetics and Pharmacodynamics: An Integrated Textbook and Computer Simulations 2nd Edition

  By: Sara E. Rosenbaum, Ph.D.
  An Integrated Textbook with Computer Simulations, which provides a comprehensive account of essential pharmacokinetic and pharmacodynamic concepts. The textbook also incorporates interactive pharmacokinetic and pharmacodynamic simulation models to allow students to visualize important principles and experiment with the design of drug dosing regimens.     

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