Course Descriptions

Biomedical and Pharmaceutical Science

BPS 101

Criminal Investigation I

Specialized techniques of crime scene investigation including firearms, arson, sexual assault and homicide. Examination of physical evidence such as firearms, bloodstains, glass and other trace evidence. Use of digital photography, computer software, alternate light sources, fluorescent powders and other chemical fingerprint techniques. Fingerprint comparisons. Court presentation.

BPS 102

Criminal Investigation II

Specialized techniques of crime scene investigation including firearms, arson, sexual assault and homicide. Examination of physical evidence such as firearms, bloodstains, glass and other trace evidence. Use of digital photography, computer software, alternate light sources, fluorescent powders and other chemical fingerprint techniques. Fingerprint comparisons. Court presentation.

BPS 136

The Oceans and Human Health

(3 crs.) Integrates chemistry, biology, toxicology and biogeochemistry to understand the relationship between the oceans and their effect on human health. (Lec. 3) (A1) (B2)

BPS 201

How Drugs Work

(3 crs.) Drug actions, uses, and adverse effects of prescription and non-prescription medications, recreational drugs, and nutritional supplements. General audience. (Lec. 3/Online) For all majors except Pharmacy_PMD, PharmaceuticalScience_BS, and Neuropharmacology_BS. (A1)

BPS 203

Herbal Medicines and Functional Food

(3 crs.) Study of traditional herbal medicines, commonly used medicinal plants, and modern plant-derived drugs. Medicinal foods, herbal supplements, and plant extracts (nutraceuticals) for health benefits beyond basic nutrition. (Lec. 3) Intended for freshmen and sophomores. (A1) (B4)

BPS 204G

Nanotechnology: It's a Small World

(3 crs.) Cross-listed as (BPS), CHE 204G. Introduction to fundamental concepts of nanotechnology and its applications, while also providing a basic understanding of the social and ethical implications of implementing nanotechnology in everyday life. (Lec. 3) (A1) (B4) (GC)

BPS 205G

The Challenged Brain

(3 crs.) Cross-listed as (BPS), PSY 205G. Equips students with knowledge about ways that central nervous system functioning can be challenged either by disease, injury, or alternate ways of functioning. (Lec. 3) (A1) (B4) (GC)

BPS 206

Foundations of Cannabis Studies

(3 crs.) The history, regulation, and ethics related to cannabis use are explored. The endocannabinoid system and cannabinoid pharmacology are introduced. (Lec. 3) Pre: Open to students in the cannabis studies minor or by permission of program director.

BPS 208G

Building New Organs with Tissue Engineering

(3 crs.) Introduces students to the fundamental concepts of tissue engineering and regenerative medicine, and provides them with theoretical information on growing and testing artificial organs in the lab, while discussing the ethical and societal implications of developing and applying artificially engineered tissues and organs in medicine. (Lec. 3) (A1) (GC)

BPS 240

Introduction to Biomedical Research

(3 crs.) Cross-listed as (CMB) BPS 240. Provide a comprehensive introduction to biomedical research, and will emphasize best practices in experimental design, data management and analysis, biomedical career preparation, and computational skills development. (Lec., Online, Workshop) Pre: BIO 101 or BIO 110 or permission of instructor.

BPS 250

Professional Development and Careers in Pharmaceutical Science

(1 cr.) Seminar discussions for the purpose of developing understanding of the fields of study, potential careers within the broad area of Pharmaceutical Sciences and fostering career and employment readiness skills. (Seminar) Pre: Sophomore standing in BSPS program or permission of instructor.

BPS 301

Pharmaceutics I: Biopharmaceutics

(2 crs.) Application of kinetics to stability, dissolution, absorption, and other biopharmaceutical processes. Bioavailability and generic equivalence. (Lec. 2) Pre: BSPS majors with junior standing and above. CHE students by permission number only.

BPS 306

Essential Pharmacokinetic Concepts

(2 crs.) Designed for students who are interested in careers in the pharmaceutical industry but who do not wish to become specialists in pharmacokinetics. (Lec. 2) Pre: BPS 301, admitted to BSPS majors, and PHARM degree-granting college designation.

BPS 312

Cannabis Chemistry and Pharmacognosy

(3 crs.) Natural products produced by the cannabis plant will be described along with methods for their extraction/purification. The genetic basis for strain variability and the entourage effect will be explored. (Lec. 3) Pre: BPS 206.

BPS 313

Principles of Medicinal Chemistry

(2 crs.) Physico-chemical properties of drug molecules; and principles needed to understand chemical basis of pharmacology and therapeutics, pharmacophores for drugs used to treat disease, and structure-activity relationships of drug-target interactions. (Lec. 2) Pre: CHM 228 and BSPS majors with junior standing or above.

BPS 314

Cannabis Therapeutics

(3 crs.) Therapeutic effects of cannabis on various medical conditions will be investigated by exploring physiology, pathophysiology, and cannabinoid pharmacodynamics. Adverse effects, drug interactions, and other precautions will be examined. (Lec. 3) Pre: BPS 206.

BPS 315

Pharmaceutics II

(4 crs.) Students will learn the physicochemical properties of drug molecules and excipients as well as formulation, manufacturing, and quality control of sterile and non-sterile solid, semi-solid, liquid and specialty dosage forms. (Lec. 4) Pre: Admitted to Pharmaceutical Science BS and PHARM degree-granting college designation, or by permission of instructor.

BPS 316

Cannabis Product Development

(3 crs.) The process of developing safe, reliable cannabis products will be examined from plant material to finished product. Extraction, separation, and analytical techniques will be discussed followed by formulation and GMPs. (Lec. 3) Pre: BPS 206

BPS 318

Pharmacy Technology Laboratory

(2 cr.) Prescription processing and compounding techniques for pharmaceutical dosage forms. (Lab. 3, Rec. 1) Pre: first-year Doctor of Pharmacy professional student or permission of instructor.

BPS 319

ADME-PK Fundamentals

(3 crs.) Fundamental principles of drug Absorption, Distribution, Metabolism, Excretion, and Pharmacokinetics (ADME-PK) including concepts, processes, mechanisms and calculations which control the concentration of therapeutically active drug in the plasma and at the site of action. Application of kinetics to dissolution, absorption, and other biopharmaceutical processes. Mechanisms of individual variation (pharmacogenetics, inhibitors, inducers, metabolism, transport). (Lec. 3) Pre: First-year standing in the Pharm.D. program. Students of other majors with permission of the instructor.

BPS 320

Dosage Forms

(3 crs.) The course will provide an introduction to the fundamental physicochemical principles governing the preparation and performance of sterile and non-sterile solid, semi-solid, liquid and specialty dosage forms. (Lec. 3) Pre: This course is open to first year Doctor of Pharmacy students. Students from other majors require permission of the instructor.

BPS 321

Introduction to the Principles of Pharmacology

(3 crs.) Fundamental principles of drug action with emphasis on drug-receptor interactions. Introduction to aspects of biochemistry, cell biology, cell signaling and cell and neuronal physiology important in the actions of drugs. (Lec. 3) Pre: BIO 101 or NEU 101 or instructor permission

BPS 325

Human Drug Metabolism

(2 crs.) Chemical, biochemical, genetic, clinical and pre-clinical aspects of drug metabolism. (Lec. 2) Pre: credit of concurrent enrollment in BPS 301 and BPS 313, BSPS majors, and PHARM degree-granting college designation.

BPS 333

Nursing Pharmacology

(3 crs.) Comprehensive course in nursing pharmacology that forms the basis for therapeutics. (Lec. 3) Pre: NUR 213 and 234, or RN student status or permission of instructor.

BPS 337

Foundational Pharmaceutical Sciences I

(4 crs.) Fundamental principles of major targets of drug therapy: Enzymes, G-protein-coupled-receptors, Membrane transport proteins, Steroid receptors.Mechanisms of action and drug design of medications used to treat hypertension and dyslipidemia. (Lec. 4) Pre: First professional year Doctor of Pharmacy student.

BPS 338

Biomedical & Pharmaceutical Sciences II

(3 crs.) A clear understanding of the physiology, pathophysiology, pharmacology. toxicology, medicinal chemistry, pharmaceutics, and pharmacokinetics of medications used to treat the disease indications covered in the CTS I-VI sequence. (Lec. 3) Pre: Doctor of Pharmacy professional student, P1 standing.

BPS 340

Veterinary Pharmacology

(3 crs.) Cross-listed as (BPS), AVS 340. Principles of pharmacology including pharmacokinetics and pharmacodynamics, drug indications, usages and side effects, practical applications of drugs including drug handling, dosing calculation and administration methods. (Lec. 3) Pre: for AVS students: AVS 331 and 333 or permission of instructor; Pre: for BSPS and Pharm.D. students: 2nd or 3rd year standing.

BPS 345

Introduction to Pharmaceutical Research

(3 crs.) Provide students with the basic skills necessary for entering the research laboratory environment and provide education for laboratory safety, compliance, ethical issues, and experimental design/analysis. (Lec. 2, Lab. 1) Pre: BSPS or INP major and at least sophomore standing.

BPS 352

Personal Cosmetics

(3 crs.) Formulation and manufacture of various types of personal cosmetics and toilet preparations. Examples of types studied are prepared in laboratory. (Lec. 2, Lab. 3) Pre: first-year Doctor of Pharmacy professional student in good standing or permission of instructor.

BPS 401

Pharmaceutical Pharmacology I

(3 crs.) Mechanisms underlying both the therapeutic and toxic actions of currently available drugs including Autonomic and Central Nervous system agents and Cardiovascular system agents. First of 2-semester sequence. (Lec. 3) Pre: BSPS majors with junior standing or above, and BIO 222, and CMB 311. Not for graduate credit.

BPS 402

Pharmaceutical Pharmacology II

(3 crs.) Mechanisms underlying both the therapeutic and toxic actions of most currently available drugs including Cholinergic nervous system, Eicosanoids, Bronchodilators, Endocrine hormones, Antibiotics/antifungal/antivirals, Cancer chemotherapy, Anticoagulants, Dyslipidemia. Second of 2-semester sequence. (Lec. 3) Pre: BS Pharmaceutical Sciences major and BPS 401.

BPS 403

Pharmacokinetics I

(3 crs.) Pharmacokinetics of drug distribution, metabolism, and elimination. Compartmental models, pharmacokinetic modeling, development of dosage regimens. (Lec. 3) Pre: second-year Doctor of Pharmacy student in good standing; or permission of the instructor.

BPS 410

Foundations for Human Disease V: GI, Endocrine

(2 crs.) Cross-listed as (PHP), BPS 410. The etiology, pathogenesis, symptomatology, and diagnosis of endocrine, and gastrointestinal diseases. (Lec. 2) Pre: P3 standing in the Doctor of Pharmacy program.

BPS 411

Biostatistics II

(4 crs.) Cross-listed as (STA), PHP, BPS 411. An overview of statistical methods with applications to health-related studies. Chi-square tests, effect measures, analysis of variances, multiple comparison procedures, linear and logistic regression, some nonparametric and survival tests. (Lec. 3, Rec. 1) Pre: STA 307, or 308, or 409, or permission of instructor.

BPS 415

Immunology and Immunotherapeutics

(3 crs.) Cross-listed as (BPS), PHP 415. The pathogenesis, etiology, epidemiology, symptomatology, and diagnosis and treatment of autoimmune diseases. The pharmacology and medicinal chemistry of anti-inflammatory, immunosuppressives, and solid-organ graft rejection medications. (Lec. 3) Pre: Second-year Doctor of Pharmacy student (P2) or permission of the instructor. Open to BSPS students.

BPS 418

Self-Care Therapeutics and Nonprescription Drugs 2

(3 crs.) Cross-listed as (PHP), BPS 418. Continued development of self-care principles, foundational knowledge about use of self-care products, and integration of clinical reasoning skills in development of a self-care plan. (Lec. 3) Pre: second-year Doctor of Pharmacy Student; PHP 315.

BPS 422

Endocrine, Gastrointestinal, and Biotechnologic Drugs

(2 crs.) Mechanisms of action of drugs used to treat endocrine and gastrointestinal disorders. Biological and biotechnologic sources, isolation, design, and medicinal chemistry of biopolymer drugs. (Lec. 2) Pre: second-year Doctor of Pharmacy student in good standing; or permission of the instructor.

BPS 425

GMPs in the Manufacture of Pharmaceutical Products

(3 crs.) Application of current Good Manufacturing Practices to the manufacture and quality control of various pharmaceutical products. (Lec. 3) Pre: BSPS majors with junior standing or above and BPS 315. CHE majors with permission number. Not for graduate credit.

BPS 426

cGMP Environmental Risks, Control and Monitoring

(3 crs.) Principles of clean room design and operations for the pharmaceutical and biotechnology industry. Reviews clean room operations and monitoring fundamentals. Monitoring and sampling will be performed in a cGMP environment. (Lec. 2, Lab 1) Pre: Students enrolled in Pharmaceutical Sciences BS, Pharmacy PMD, Pharmaceutical Manufacturing & Formulation Minor, or Biomedical and Pharmaceutical Sciences Minor, or by permission of instructor. Not for graduate credit.

BPS 432

Neuropharmacology in the CNS

(3 crs.) Pharmacology of therapeutics for conditions involving central nervous system function, specifically addressing pharmaceutic approaches and neurological effects. (Lec. 3) Pre: BIO101 (or BIO110 or NEU101) and BPS321; or instructor permission. Not for graduate credit.

BPS 436

Psychotropic Drugs and Therapy

(3 crs.) Cross-listed as (BPS), PSY 436. Interaction of drug and non-drug therapy and of physiological and psychological origins of psychopathology. Intended for advanced undergraduate and graduate students interested in clinical psychology. (Lec. 3) Pre: any one of the following--BIO 101, 104B, 113, 121, PSY 381, or permission of instructor. Not for graduate credit.

BPS 437

Biomedical & Pharmaceutical Sciences III

(3 crs.) A clear understanding of the physiology, pathophysiology, pharmacology. toxicology, medicinal chemistry, pharmaceutics, and pharmacokinetics of medications used to treat the disease indications covered in the CTS I-VI sequence. (Lec. 3) Pre: Doctor of Pharmacy professional student. P2 standing. Not for graduate credit.

BPS 438

Biomedical & Pharmaceutical Sciences IV

(3 crs.) A clear understanding of the physiology, pathophysiology, pharmacology. toxicology, medicinal chemistry, pharmaceutics, and pharmacokinetics of medications used to treat the disease indications covered in the CTS I-VI sequence. (Lec. 3) Pre: Doctor of Pharmacy professional student. P2 standing. Not for graduate credit.

BPS 442

Pharmacogenetics and Pharmacogenomics

(3 crs.) Principles of how genetic and genomic factors contribute to individual variation in drug response and how these principles can be used to produce effective and safe drugs. (Lec. 3) Pre: CMB 311 and BPS 321.

BPS 443

Formulation and Manufacturing Laboratory

(2 crs.) Provides general principles and hands-on experience in the preformulation, formulation, manufacturing, and quality control fields that are necessary in design, formulation, compounding and manufacturing of drug dosage forms. (Lab. 4) Pre: BSPS majors with junior standing or above and BPS315.

BPS 445

Natural Product Drugs

(3 crs.) Discovery, development, biosynthesis and general fundamental properties of natural product drugs. (Lec. 3) Pre: CHM 228; CMB 201 or equivalent.

BPS 446

Biotechnology, Biologics, and Biosimilars

(3 crs.) Provides basic knowledge on medical biologics. Covers a full spectrum of topics from general concepts, biologics production, manufacture, safety evaluation, regulatory affairs, pharmacodynamics and pharmacokinetics to therapeutic applications. (Lec. 3) Pre: BIO 101 and CMB 311. Not for graduate credit.

BPS 450

Practical Tools for Molecular Sequence Analysis

(3 crs.) Cross-listed as (CMB), BPS 450. Introduction to practical ways to analyze DNA, protein and genome datasets. Students will be introduced to computing environments and publicly available software tools for analysis. (Lec. 2, Lab. 2) Pre: CMB 311 or BIO 352 (or CMB 352) or BIO 341 or permission of instructor. Not for graduate credit.

BPS 451

Techniques in Medicinal Chemistry and Molecular Biology

(4 crs.) Provides students with technical skills of medicinal chemistry, molecular biology, and drug analysis commonly used in pharmaceutical industry. Technical writing in the form of lab reports. (Lab. 4) Pre: BPS 345, BSPS majors with senior standing, and PHARM degree-granting college designation. .

BPS 455

Protein Molecular Modeling for Biomedical Sciences

(3 crs.) Cutting edge computer software to study the 3D-structure of proteins/RNA/DNA of biomedical interest. Application of course topics will be required via case study or research project. (Lec. 3) Pre: CMB 311 and CHM 227. Not for graduate credit.

BPS 460

Pharmaceutical Science Internship/Field Experience

(0, 3, 6, 9, or 12 crs.) Undergraduate BS Pharmaceutical Science majors completing approved Off Campus Experience. Fall, Spring, or Summer Semester. Registration is by permission number only. (Practicum) Pre: Permission number required. May be repeated for a maximum of 12 credits. Not for graduate credit. S/U only.

BPS 497

Special Problems

(1-5 crs.) Methods of carrying out a specific research project. Literature search, planning, laboratory work, writing an acceptable report. (Independent Study) Pre: permission of chairperson. Not for graduate credit.

BPS 498

Special Problems

(1-5 crs.) Methods of carrying out a specific research project. Literature search, planning, laboratory work, writing an acceptable report. (Independent Study) Pre: permission of chairperson. Not for graduate credit.

BPS 502

Drug Development

(3 crs.) Cross-listed as (BPS) PHC 502. Scientific and regulatory aspects of drug development from discovery to market, exemplified by URI research. (Accelerated Online Program) Pre: graduate standing in Pharmacy or permission of instructor.

BPS 503

Pharmacokinetics and Pharmacodynamics for Scientists

(3 crs.) Presents the principles of pharmacokinetics and pharmacodynamics with specific emphasis on their application in pharmaceutical science. Pre: MTH 131.

BPS 504

Pharmacokinetics II

(3 crs.) Applied pharmacokinetics, principles of clinical pharmacology, therapeutic drug monitoring and dose individualization. (Lec. 3) Pre: BPS 403, third-year Doctor of Pharmacy student in good standing; or permission of the instructor. Offered every fall semester.

BPS 506

Chemistry, Manufacturing and Controls for Biopharmaceuticals

(3crs.) This course focuses on the chemistry, manufacturing, and controls (CMC) for the development of biopharmaceutical products. CMC is a major part of the Biologics License Application (BLA) ensuring the drug is safe and effective over its lifecycle.

BPS 510

Biopharmaceutical Regulatory Compliance and Product Quality

(3 crs.) This course focuses on the key concepts associated with regulatory compliance, quality assurance and overall drug product quality for biopharmaceuticals particularly in relation to product development. (Online) Pre: Graduate standing in the College of Pharmacy or by permission of instructor.

BPS 512

Biologics and Biosimilars

(3 crs.) A comprehensive overview of biologics and biosimilars from discovery to FDA approval including target identification, manufacturing, quality control, regulatory approval, and delivery and pharmacoeconomic considerations. (Online) Pre: BPS 502, graduate standing in the College of Pharmacy, or by permission of instructor.

BPS 519

Self-Care II

(3 crs.) Cross-listed as (PHP), BPS 519. Expansion of nonprescription and complementary medicine therapeutics. Explore the implementation of pharmaceutical care programs in community pharmacy practice. (Lec. 3) Pre: PHP 418 (or BPS 418); third-year Doctor of Pharmacy professional student.

BPS 520

Cannabinoid Pharmacology

(3 crs.) Investigates the endocannabinoid system and the use of cannabinoids to modulate biological processes. Explores delivery modes, bioavailability, mechanism of action, and therapeutic potential of the major cannabinoids. (Online)

BPS 521

Cancer Chemotherapy and Toxicology

(3 crs.) Pharmacology and medicinal chemistry of oncology drugs. Principles of toxicology. (Lec. 3) Pre: third-year Doctor of Pharmacy student in good standing, or permission of the instructor.

BPS 522

Cannabis Extraction Processes and Laboratory Testing

(3 crs.) Explores relevant extraction processes of the Cannabis plant to ultimately isolate metabolites (cannabinoids and terpenes). Examines laboratory testing procedures and workflows for composition analysis, contaminant analysis, and quantification. (Online)

BPS 523

Formulation and Manufacturing of Cannabis Products

(3 crs.) Guides students through the process of developing safe and functional cannabis products. Explores formulation development and good manufacturing practices (GMPs) to produce safe and reliable products. (Online)

BPS 524

Analytical and Bioanalytical Techniques in Cannabis Science

(3 crs.) Examine innovative techniques for cannabis product and biological matrix analysis for cannabinoids and their metabolites. Instrument operation and the use of mass spectrometry in pharmacokinetic analysis will be explored. (Online)

BPS 525

Experimental Techniques in Biomedical Sciences

(4 crs.) Provides experience with a variety of techniques used in biomedical science research, including HPLC, NMR, polarimetry, biotransformations, solid-phase synthesis, cell fractionation, and isolation and purification of proteins. (Lab. 4)

BPS 526

Foundations of Human Disease VI: Hematology-Oncology

(2 crs.) Cross-listed as (PHP), BPS 526. The etiology, pathogenesis, symptomatology, and diagnosis of hematology and oncology diseases in people. Introduction to pharmacogenomics, gene-drug interactions, and genetic therapy in human disease. (Lec. 2) Pre: third-year Doctor of Pharmacy professional student standing. Taken concurrently with BPS 521 and PHP 513. Not for graduate credit.

BPS 530

Drug Metabolism

(3 crs.) Mechanisms of Phase 1 (oxidation, reduction, hydrolysis) and Phase 2 (conjugations and synthesis) of drug metabolism. (Lec. 3) Pre: CMB 581 or permission of instructor. Offered every spring.

BPS 533

Medicinal Plants

(3 crs.) Problems in drug plant chemotaxonomy with field work in the drug plant gardens. Emphasis is placed on certain alkaloid, glycoside and oil-yielding plants, weedicides and insecticides as related to measures for control. (Lec. 2, Lab. 3) Pre: third-year Doctor of Pharmacy student in good standing, or permission of the instructor.

BPS 535

Pharmaceutical Biotechnology

(3 crs.) Introduction to pharmaceutical biotechnology, including drug design, DNA sequencing, cloning, recombinant proteins, monoclonal antibodies, and drug-screening techniques. (Lec. 3) Pre: CMB 581 or permission of instructor.

BPS 536

Biotechnology Product Evaluation and Development

(3 crs.) Cross-listed as (MLS 571), BPS 536. The process through which candidate products produced using recombinant DNA technology are evaluated for safety and efficacy, including conductance of clinical trials, economic issues, and regulatory affairs. (Lec. 3/Online) Pre: graduate standing and permission of chairperson.

BPS 537

Biomedical & Pharmaceutical Sciences V

(3 crs.) A clear understanding of the physiology, pathophysiology, pharmacology. toxicology, medicinal chemistry, pharmaceutics, and pharmacokinetics of medications used to treat the disease indications covered in the CTS I-VI sequence.(Lec. 3) Pre: Doctor of Pharmacy professional student. P3 standing. Not for graduate credit.

BPS 538

Biomedical & Pharmaceutical Sciences VI

(2 crs.) A clear understanding of the physiology, pathophysiology, pharmacology. toxicology, medicinal chemistry, pharmaceutics, and pharmacokinetics of medications used to treat the disease indications covered in the CTS I-VI sequence. (Lec. 2) Pre: Doctor of Pharmacy professional student. P3 standing. Not for graduate credit.

BPS 540

Advanced Drug Delivery Systems

(3 crs.) Cross-listed as (BPS), CHE 540. The course will present the design and principles of advanced drug delivery systems, which have specified drug delivery profiles and significant advantages in therapeutics over conventional dosage forms. (Lec. 3) Pre: Graduate standing or BPS 315.

BPS 542

Bioinformatics I

(3-4 crs.) Cross-listed as (CSC), STA, CMB 522, BPS 542. Integrates computing, statistical, and biological sciences, algorithms, and data analysis/management. Multidisciplinary student research teams. Modeling dynamic biological processes. Extra project work for 4 credits. (Lec. 3, Project 3) Pre: major in a computing, statistical, or biological science or permission of instructor.

BPS 546

Advanced Toxicology

(3 crs.) Toxic effects of selected drugs and other xenobiotics on physiological and biochemical processes. (Lec. 3) Pre: permission of instructor. Offered every third year.

BPS 547

Precision Medicine & Applied Pharmacogenomics

(3 crs.) Cross-listed as (BPS), PHP 547. Concepts in precision medicine and pharmacogenomics with application to patient-specific drug therapy regimens are explored. (Lec. 3) Pre: Third professional year PharmD student or permission of instructor. Not for graduate credit.

BPS 550

Practical Tools for Molecular Sequence Analysis

(3 crs.) Cross-listed as (CMB), BPS 550. Students will be introduced to practical ways to analyze DNA, protein and genome datasets. Students will be introduced to computing environments and publicly available software tools for analysis. Pre: CMB 311 or BIO/CMB 352 or BIO 341 or permission of instructor.

BPS 551

Chemistry of Natural Products

(3 crs.) Introduction to chemistry of certain groups of natural products especially in relation to their chemotaxonomic position in plant classification. Topics limited to secondary metabolites; e.g., terpenoids, phenolic compounds, aromatic compounds, phytosterols, alkaloids. (Lec. 3) Pre: CHM 228 and CHM 230. In alternate years.

BPS 552

Advanced Medicinal Chemistry

(3 crs.) Covers didactic topics of medicinal chemistry: Drug Discovery, Design, and Development; Drug-Receptor Interactions; Mechanisms of Enzyme Catalysis and Cofactors; Enzyme Inhibition and Inactivation; DNA Interactive Agents; Drug Metabolism; Prodrugs and Drug Delivery Systems. Pre: Introductory Organic Chemistry and permission of instructor.

BPS 553

(550) Bionanotechnology

(3 crs.) Cross-listed as (CHE), BPS 553. Principles and applications of bionanotechnology. Intermolecular forces, self-assembly, biomolecular structure, biological processes, molecular manufacturing, and surface functionalization for designing biodevices and nanomaterials. Overview of current and emerging technologies, safety and ethics. (Lec. 3) Pre: Graduate standing; or BPS 315 and CHM 112.

BPS 555

Protein Molecular Modeling for Biomedical Sciences

(3 crs.) Cutting edge computer software to study the 3D-structure of proteins/RNA/DNA of biomedical interest. Application of course topics will be required via a research project to create new knowledge. (Lec. 3) Pre: graduate standing.

BPS 557

Modern Spectroscopic Techniques in Drug Discovery

(3 crs.) Introduces spectroscopic techniques needed to understand data from contemporary biomedical science research, especially macromolecular NMR spectroscopy. Focused on developing data interpretation skills, and the ability to critically evaluate current practices. (Lec. 3) CHM 227 or equivalent, or permission of instructor. Open to undergraduates in Chemistry and BSPS program at the junior and senior levels.

BPS 565

Pharmacokinetics

(3 crs.) The principles and application of clinical pharmacokinetics for advanced pharmacy students. Developing, modifying, and evaluating dosage regimens. (Lec. 3)

BPS 587

General Pharmacology

(3 crs.) An introduction to principles of pharmacology and major drug categories, for graduate students and advanced undergraduate students in biological sciences. (Lec. 3) Pre: permission of instructor

BPS 597

Special Problems

(1-3 crs.) Special graduate student project assignments in research under the supervision of faculty. (Independent Study) Pre: graduate standing. May be repeated for a maximum of 6 credits.

BPS 598

Special Problems

(1-3 crs.) Special graduate student project assignments in research under the supervision of faculty. (Independent Study) Pre: graduate standing. May be repeated for a maximum of 6 credits.

BPS 621

Manufacturing Pharmacy I

Theory and practice in the manufacture of pharmaceuticals and the principles of operation of the equipment used for their production. (Lec. 2) In alternate years.

BPS 622

Manufacturing Pharmacy II

(3 crs.) Theories applied to the manufacture of pharmaceuticals with an emphasis on formulation considerations and principles of operation of equipment used for their production. (Lec. 3) Pre: BPS 621. In alternate years.

BPS 623

Manufacturing Pharmacy Laboratory

(2 crs.) Practical application of the principles of all aspects of dose-form manufacture, including an emphasis on good manufacturing practices. (Lab.) Pre: credit or concurrent enrollment in 622.

BPS 625

Advanced Physical Pharmacy

(4 crs.) Theory and application of physical chemical principles to problems in pharmaceutical research, with emphasis on methods by which properties of new medicinal agents are determined. (Lec. 4) Pre: permission of instructor.

BPS 626

Advanced Physical Pharmacy Laboratory

(1 cr.) Laboratory exercises dealing with the physical-chemical principles used in the evaluation of pharmaceutical substances. (Lab. 4) Pre: permission of instructor.

BPS 633

Biosynthesis

(3 crs.) Biogenesis of medicinally active principles of biological origin. Emphasis given to organic acids, polysaccharides, glycosides, steroids, and certain nitrogenous compounds. (Lec. 3) In alternate years.

BPS 635

Pharmacognosy Techniques

(3-4 crs.) Physical and chemical factors influencing growth and development of active principles of drug plants. Certain biological analyses of results are performed. (Lec. 1, Lab. 6-9)

BPS 641

Biochemical Pharmacology

(3 crs.) Theory and application of pharmacological studies at the cellular and subcellular levels and their significance to drug action in the intact organism. (Lec. 2, Lab. 3) Pre: permission of instructor. Offered every third year.

BPS 642

Biochemical Toxicology

(3 crs.) Cross-listed as (BPS), CMB 642. Biochemical and molecular aspects of chemically induced cell injury and chemical carcinogenesis. (Lec. 3) Pre: permission of instructor. Offered every third year.

BPS 644

Cardiovascular Pharmacology

(3 crs.) Cellular mechanisms of drug action as a basis for understanding therapeutic effects. Emphasis on current developments in antihypertensive, antiarrhythmic, antianginal, and cardiotonic drug research. (Lec. 3) Pre: permission of instructor. Offered every third year.

BPS 660

Industrial Project (Pharmaceutics)

(3 crs.) A research project directed by the major professor on a topic in industrial pharmacy. A report must be submitted to the department faculty. The project will normally be conducted off campus. (Lab.) Pre: graduate standing in pharmaceutics.

BPS 670

Advanced Pharmacokinetics

(3 crs.) Application of classical compartmental and noncompartmental analyses to pharmacokinetics and pharmacodynamics emphasizing the use of PKPD analysis employed in the pharmaceutical industry. Pre: BPS 403 or permission of instructor. Graduate standing or in good standing in the P2-P4 years of the Pharm.D. curriculum.

BPS 697

Research in Biomedical and Pharmaceutical Sciences

(1-3 crs.) Literature survey, laboratory work, and a detailed research report on one or more assigned topics. (Independent Study)

BPS 698

Research in Biomedical and Pharmaceutical Sciences

(1-3 crs.) Literature survey, laboratory work, and a detailed research report on one or more assigned topics. (Independent Study)