Trends in the antimicrobial susceptibility of bacteremias over the past decade: a regional antibiogram of the ESKAPE pathogens

Presented at the 49th Annual Drug Information Association Meeting, June 2013
Ajinkya M Pawar, BS(1), Kerry L LaPlante, PharmD(1,2,3) and Aisling R Caffrey, PhD, MS(1,2)

Research

Background: Bacteremias are associated with negative clinical outcomes and high mortality rates. Such infections are extremely difficult to treat, particularly as antibiotic resistance rates change, potentially leading to the administration of inappropriate empiric therapies.
Objectives: To develop and evaluate a 10-year regional antibiogram of ESKAPE pathogens from blood cultures: Enterococcus faecium and faecalis, Staphylococcus aureus, Klebsiella pneumoniae, Acinetobacter species, Pseudomonas aeruginosa, and Enterobacteriaceae (Escherichia coli, Proteus mirabilis).
Related People: Aisling R Caffrey and Kerry L LaPlante
(1)College of Pharmacy, University of Rhode Island, Kingston, RI, USA
(2)Infectious Diseases Research Program, Providence Veterans Affairs Medical Center, Providence, RI, USA;
(3)Warren Alpert School of Medicine, Brown University, Providence, RI, USA.