Located in Lab Module 380 on Level 3 of Avedisian Hall
Based at the University of Rhode Island, our lab is working on gene-environment interactions, with a special emphasis on the epigenetics of Alzheimer’s disease. Under the direction of Principal Investigator, Dr. Nasser H. Zawia, NL has identified novel drugs for the treatment of AD as well as identified biomarkers for the disease.
If Professor Nasser H. Zawia succeeds in his quest for an effective new treatment for Alzheimer’s disease—and the evidence so far suggests he will—it will be more than a medical triumph with the potential to benefit millions. It will be proof that there is still room in this age of profit-driven drug development for a researcher primarily motivated by empathy and a passion for science.
Researchers striving to understand the origins of dementia are building the case against a possible culprit: lead exposure early in life. A study spanning 23 years has now revealed that monkeys who drank a lead-rich formula as infants later developed tangles of a key brain protein, called tau, linked to Alzheimer’s disease. Though neuroscientists say […]
With the largest private donation in its history, The University of Rhode Island will establish a neuroscience research institute named for the parents of Thomas M. Ryan, a 1975 pharmacy graduate of the University and former chairman, president and CEO of CVS Caremark. Tom and his wife Cathy have donated $15 million to establish the George […]
The University of Rhode Island has received a $15-million gift to establish a research institute focused on understanding and treating neurodegenerative diseases such as Alzheimer’s and Parkinson’s. The gift, from former CVS Caremark CEO Thomas M. Ryan and his wife, Cathy, aims to catalyze a statewide collaboration, linking with Brown University and local hospitals to […]
The George & Anne Ryan Institute for Neuroscience is engaging scientists and students in solving some of the most pressing health care challenges we face today, thanks to the generosity of the largest private donation in URI history. Thomas M. Ryan, a 1975 College of Pharmacy graduate and former chairman, president and CEO of CVS […]
Discover New Cures. The world’s got a lot of illness and disease that needs curing, and at URI, leading scientists are breaking new ground toward the discoveries we’ve all been waiting for. Inside our Natural Products Lab, Pharmacognosy Professor David Rowley – one of the only a handful of marine microbial chemists in the world […]
Children exposed to lead in old paint, Victorian water pipes and unsafe toys could be at risk of Alzheimer’s later in life, scientists have said. A study shows that even small amounts of the dangerous metal in the first few years can cause changes in the brain associated with the devastating disease. Although lead has […]
Nasser Zawia, a URI professor of biomedical sciences at the College of Pharmacy led the three-year study, which involved four institutions.“This is the first evidence of promotion of Alzheimer’s disease-like pathology in a primate by an environmental agent,” Zawia said. “It is relevant because monkeys have identical genes to humans.”
URI Pharmacy professor discovers enhanced Alzheimer’s plaques in monkey tissue KINGSTON, R.I. — January 9, 2008 – A University of Rhode Island pharmacy professor has found for the first time evidence of Alzheimer’s-like disease in monkeys that were exposed to lead as infants. Nasser Zawia, a URI professor of biomedical sciences at the College of […]
Lead poisoning in infancy may make Alzheimer’s disease more likely decades later, a new study shows. Lead poisoning is a well-known danger, especially for young children. Months or years of lead poisoning can stunt children’s growth and damage their brain, kidneys, hearing, and mental development. Early lead poisoning may also tinker with genes in a […]