College of Pharmacy

7 Greenhouse Road Kingston, RI 02881

pharmcol@etal.uri.edu – Office: 401.874.2761 Fax: 401.874.2181

URI
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Al Bach, Ph.D.

al_bach_web
  • Research Assistant Professor
  • Office: 323 Lab: 321
  • Phone: 401.874.2527
  • Email: al_bach@mail.uri.edu
  • Mailing Address: 7 Greenhouse Road, Kingston, RI 02881

Research

NMR spectroscopy, structure elucidation and biophysical chemistry

Education

Postdoctoral Fellow, Rutgers University
Ph.D., Chemistry, University of Delaware
B.S., Chemistry, Carnegie-Mellon University

Publications

Yanxuan Cai, Oliver McConnell, Alvin C. Bach, II. Suitability of THF as a dopant and the comparison to other existing dopants in dopant-assisted atmospheric pressure photoionization mass spectrometry. Rapid Communications in Mass Spectrometry 23, 2283-2291, 2009.

Michael Kagan, Michael Chlenov, Sergey Melnikov, Oliver McConnell, Alvin C. Bach, II, Guy Carter, Amedeo Failli, Thomas J. Caggiano, Jay S. Shumsky, Dieter Lubda. Normal-phase automated mass-directed HPLC purification of a pyrrolobenzodiazepine library with vasopressin agonist activity. Journal of Combinatorial Chemistry 11, 704-709, 2009.

Alvin C. Bach, II, Walter Massefski, James F. Mattes. An automated approach to NMR data handling for compound validation and registration. Journal of Laboratory Automation 13, 73-78, 2008.

Vasilios M. Marathias, Gregory Tawa, Igor Goljer, Alvin C. Bach, II. Method for stereochemical identification of small molecules using chiral liquid crystals, NMR and modeling. American Pharmaceutical Review 10, 74-77, 2007.

Vasilios M. Marathias, Gregory Tawa, Igor Goljer, Alvin C. Bach, II. Stereochemical identification of (R)- and (S)- ibuprofen using residual dipolar couplings, NMR, and modeling. Chirality 19, 741-750 2007.

Jianyao Wang, William DeMaio, Appavu Chandrasekaran, Li Shen, Alvin C. Bach, II, Rasmy Talaat, Joanne Scatina. Mechanism study on N-dephenylation mediated through a N-para-hydroxy metabolite. Current Drug Discovery Technology 3, 101-114, 2006.

Yanxuan Cai, David Kingery, Oliver McConnell, Alvin C. Bach, II. Advantages of atmospheric pressure photoionization mass spectrometry in support of drug discovery. Rapid Communications in Mass Spectrometry 19, 1717-1724, 2005.

Purnima Khandelwal, Chad E. Beyer, Qian Lin, Lee E. Schecther, Alvin C. Bach, II. Studying rat brain neurochemistry using nanoprobe NMR spectroscopy: a metabonomics approach. Analytical Chemistry 76, 4123-4127, 2004.

Purnima Khandelwal, Chad E. Beyer, Qian Lin, Paul McGonigle, Lee E. Schechter, Alvin C. Bach, II. Nanoprobe NMR spectroscopy and in vivo microdialysis: new analytical methods to study brain neurochemistry. Journal of Neuroscience Methods 133, 181-189 2004.

Karyn T. O’Neil, Alvin C. Bach, II, William F. DeGrado. Structural Consequences of an amino acid deletion in the B1 domain of Protein G. PROTEINS: Structure, Function, and Genetics 41, 323-333, 2000.

Alvin C. Bach, II, Charles J. Eyermann, John D. Gross, Michael J. Bower, Richard L. Harlow, Patrica C. Weber and William F. DeGrado. Structural studies of a family of high affinity ligands for GPIIb/IIIa. Journal of the American Chemical Society 116, 3207-3219, 1994.

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