Human Integrative Physiology (HIP) Lab

Research

Dr. Adami research focuses on the mechanisms of muscle dysfunction in chronic diseases and the responses of the cardiovascular system to different stimuli like exercise and simulated microgravity. She is particularly interested in skeletal muscle oxygen delivery and utilization, and in understanding the mechanisms limiting them in health and disease. Her research mission is the use of exercise both as a research tool to investigate integrative physiological health, and as an intervention to improve health and quality-of-life of the wider population.

Projects

  • Determinations of 5 years progression of muscle dysfunction and inactivity in COPDGene participants (R01HL151452) National Heart, Lung, and Blood Institute, NHLBI.
  • Changes in physical activity and quality-of-life induced by COVID-19 pandemic restrictions in smokers with and without COPD
  • Muscle Responsiveness in Lung Disease Patients Referred to Pulmonary Rehabilitation
  • Muscle oxygen diffusion by near infrared spectroscopy (NIRS)
  • Evaluation of free-living daily physical activity, and sleep behaviors, in smokers with and without COPD
  • Using non-invasive NIRS technology to measure muscle oxidative capacity in Pulmonary Arterial Hypertension (PAH)
  • Non-invasive evaluation of mitochondrial oxidative capacity in lower limb muscles in children with motor deficits (cerebral palsy)