A Simulated Cell Culture Laboratory for Student Training on Aseptic Techniques

Investigator: Jyothi Menon, University of Rhode Island Scientific Theme: Environmental Health Sciences Abstract: Early biomedical research experiences are critical for generating enthusiasm, especially among students from underrepresented backgrounds, to consider a STEM career. However, opportunities for student training on essential lab skills like aseptic cell culture techniques in traditional in-person settings are limited due to […]

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An Interactive Online Organic Chemistry Textbook With Biomedical Applications

Investigator: Seann Mulcahy, Providence College Scientific Theme: Environmental Health Sciences Abstract: The COVID-19 pandemic has caused a tremendous upheaval in the conventional teaching modalities in higher education. Over the past year, in-person content delivery, hands-on experiments, and face-to-face lectures and office hours have given way to dedensification and social distancing. This was particular difficult for […]

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Translating Research into Public Health Policy

Investigator: Todd Olszewski, Providence College Scientific Theme: Environmental Health Sciences Abstract: This project entails developing a new virtual simulation module for the capstone internship course for Providence College’s Health Policy and Management department. Based on Barnard College’s Reacting to the Past model of historical case studies, the month-long module will expose HPM majors to critical […]

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2D Game-Based Nanotechnology Lab as an Enhanced Education/Training Pedagogy

Investigator: Jie Shen, University of Rhode Island Scientific Theme: Environmental Health Sciences Abstract: The COVID-19 pandemic has significantly impacted education and training programs, and hindered research advancements in the fields of biomedical and health sciences globally. During the pandemic, remote synchronous, asynchronous, or hybrid learning modules have been quickly developed and/or adapted to deliver existing […]

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Identifying and Quantifying Drug Metabolism by the Human Gut Microbiome

INVESTIGATOR: Tyler Stack, Providence College MENTOR: Karen Allen, Boston University SCIENTIFIC THEME: Environmental Health Sciences ABSTRACT: A growing field of research is identifying the myriad of ways that gut bacteria affect human health. Among many known roles, these microbes can aid digestion, prevent infections of virulent bacteria, and impact mood by altering hormones. One growing area […]

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Towards Ultrasensitive Stochastic Sensing of Lead Ions in Blood

INVESTIGATOR: Jiyeon Kim, University of Rhode Island MENTOR: Brett Lucht, University of Rhode Island SCIENTIFIC THEME: Environmental Health Sciences ABSTRACT: This project will develop a novel technology for ultrasensitive and rapid analysis of nanomolar lead ions (Pb2+) in the blood by stochastically detecting individual Pb2+-selective polymeric nanoemulsions (NEs) at a nanopipet electrode. Lead exposure is […]

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Control of gene expression by specialized ribosomes in Francisella tularensis

INVESTIGATOR: Kathryn Ramsey, University of Rhode Island MENTOR: Steven Gregory, University of Rhode Island THEME:  Environmental Health Sciences ABSTRACT: The rising incidence of tickborne diseases is a public health threat in the United States. A particularly infectious tickborne pathogen and potential bioweapon, the Gram-negative intracellular pathogen Francisella tularensis, can be transmitted to humans through arthropod vectors, […]

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Metabolic effect of stress: Sirt 1’s role in brain homeostatic and hedonic nuclei

INVESTIGATOR: Anika Toorie, Rhode Island College THEME: Environmental Health Sciences MENTOR: Elena Oancea, Brown University ABSTRACT:  Adolescence is a critical period of development and stress incurred during this phase can affect immediate and long-term health. Glucocorticoids (GC), produced from activation of the hypothalamus-pituitary-adrenal (HPA) axis is critical in the resolution of stress. GC also regulate […]

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Chromatin organization and dynamics: Mechanisms of cancer

INVESTIGATOR: Steven Weicksel, Bryant University THEME: Cancer ABSTRACT: The 3-D organization of chromatin (chromatin topology) has been shown to play an important role in gene regulation. Some disease states (such as cancer) display changes in chromatin topology and subsequently gene regulation. Using the model organism Danio rerio (zebrafish) I will be defining the chromatin topology […]

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