Sunday, August 19

13:00-19:00: Registration

17:00-19:00: Welcome reception

19:00-19:30: Introductory remarks
Organizers and Academy hosts

19:30-20:30: Plenary Lecture
– Keynote Speaker Bob Reed (Cornell University, USA): On these expanded membranes nature writes: The evolutionary genetics of butterfly wing patterns (introduced by Simon Baxter)

20:45  Dinner

Monday, August 20, 2018

07:00-08:15  Breakfast

08:30-12:30: Morning Session: Genomics, Genetics, Evolution and Phylogeny I: Genome sequencing and mapping; comparative genomics, evolution and phylogeny; genomic and cytogenetic tools for population diagnostics and trait identification
(Session coordinators: Felix Sperling, Simon Baxter, Petr Nguyen, Wee Tek Tay)

08:30-09:00: Introductory lecture
– Featured Speaker Nick Grishin (HHMI and University of Texas Southwestern Medical Center, Dallas, USA): Phylogenomics of butterflies

09:00-10:15: Oral presentations from submissions

09:00-09:20: Shuichiro TOMITA (National Agriculture and Food Research Organization, Japan): Genetic diversity of the wild mulberry silk moth, Bombyx mandarina in Japan
09:20-09:40: Martina DALIKOVA: (Institute of Entomology, Biology Centre CAS, Czech Republic): Differences in repetitive DNA in blue butterflies (Polyommatinae, Lycaenidae)
09:40-10:00: Hamid GHANAVI (Lund University, Sweden): Multiplex PCR for phylogenetics of old genomic DNA extracts – Erebidae moths as an example
10:00-10:20: Victoria TWORT (Lund University, Lund, Sweden): From genomes to museums: Lepidoptera phylogenetics comes of age

10:20-10:50: Coffee break

10:50-12:30: Oral presentations from submissions

10:50-11:10: Maohua CHEN (Northwest A&F University, PR China): Population genetics of an invasive species, the codling moth, Cydia pomonella (L) (Lepidoptera: Tortricidae) in China
11:10-11:30: Michel CUSSON (Laurentian Forestry Centre, Natural Resources Canada): Genomic approaches aimed at preventing accidental introductions of forest invasive lepidopteran pests: the case of the Asian gypsy moth
11:30-11:50: Sandrine PICQ (Laurentian Forestry Centre, Natural Resources Canada): The calm before the storm: a study of the genomic population structure of the eastern spruce budworm, Choristoneura fumiferana, during the rising phase of an outbreak
11:50-12:10: Felix SPERLING (University of Alberta, Canada): Integration of genomic and functional aspects of spruce budworm species delimitation

12:10-12:30: Poster introductions I

Bernhard Gschloessl: Genomic and transcriptomic resources of two Lepidoptera : the Notodontidae Thaumetopoea pityocampa and the Crambidae Ostrinia scapulalis
Camille Meslin-Auclair: Dynamic evolution of the multigene family of gustatory receptors in the moth Spodoptera littoralis

13:00  Lunch

14:30-15:30: Poster viewing I

15:30-17:00: Afternoon special
Afternoon special: Networking and funding initiatives for emerging agricultural and forest pests and systems for pest control (coordinated by Emmanuelle d’Alençon, Astrid Groot, Michel Cusson, Paul Shirk, Tom Walsh)
To be organized and announced on site by coordinators

17:00-17:30: Coffee break

17:30-20:10 Evening Session: Genomics, Genetics, Evolution and Phylogeny II: Mono-, oligo- and polyphagy of herbivores; species adaptation and invasiveness; insecticide resistance and detoxification
(Session coordinators: Wee Tek Tay, Simon Baxter, Michel Cusson, Tom Walsh)

17:30 -18:00: Introductory lecture
– Featured Speaker Tom Walsh (CSIRO Black Mountain Laboratories, Australia): Australian bollworms, Helicoverpa armigera and Helicoverpa punctigera; Bt resistance mechanisms and genomics

18:00-19:00: Oral presentations from submissions

18:00-18:20: Emmanuelle d’ALENÇON (INRA, University of Montpellier, France): Integrative study of adaptation and speciation in the Noctuid moth Spodoptera frugiperda
18:20-18:40: Richard Newcomb (New Zealand Institute for Plant & Food Research and University of Auckland, New Zealand): Genomics and functional genomics of an invasive, polyphagous lepidopteran pest – the light brown apple moth, Epiphyas postvittana
18:40-19:00: Karl GORDON (CSIRO Black Mountain Laboratories, Australia): Beyond the Helicoverpa genomes – gene family expansions, adaptation and selective sweeps 

19:00-19:10: Break

19:10-20:10: Oral presentations from submissions

19:10-19:30: Wee Tek TAY (CSIRO Black Mountain Laboratories, Australia): Lepidopteran genomes on the move: Understanding introductions and founder frequencies
19:30-19:50: Simon BAXTER (University of Adelaide, Australia): Combining deleterious ABC transporter C2 alleles of independent origin causes field resistance to insecticidal Bt toxins
19:50-20:10: Corinna KREMPL (Max Planck Institute for Chemical Ecology, Germany): Detoxification of gossypol, a cotton secondary metabolite, by Heliothine moths

20:30  Dinner

Tuesday, August 21, 2018

07:00-08:15  Breakfast

08:30-12:45: Morning Session: Development and Differentiation I: Sex determination; control of development and metamorphosis; reproduction
(Session coordinators: Frantisek Marec, Toru Shimada, Astrid Groot)

08:30-09:00: Introductory lecture
– Featured Speaker Susumu Katsuma (University of Tokyo, Japan): The feminizer piRNA – masculinizer gene system determines the sex in Bombyx

09:00-10:20: Oral presentations from submissions

09:00-09:20: Petr NGUYEN (Institute of Entomology, Biology Centre CAS and University of South Bohemia, Czech Republic): Sex chromosome evolution in lycaenid butterflies (Lycaenidae)
09:20-09:40: Irena HLADOVA (Institute of Entomology, Biology Centre CAS, Czech Republic): Karyotype and sex chromosome evolution of small ermine moths of the genus Yponomeuta
09:40-10:00: Anna VOLENIKOVA (Institute of Entomology, Biology Centre CAS and University of South Bohemia, Czech Republic): On the origin of sex chromosomes in Lepidoptera: The past, present, and future
10:00-10:20: Atsuo Yoshido (Institute of Entomology, Biology Centre CAS, Ceske Budejovice, Czech Republic): Evolution of complex sex chromosome systems in Leptidea wood white butterflies

10:20-10:50: Coffee break

10:50-11:10: Oral presentations from submissions

11:10-11:30: Frantisek Marec (Institute of Entomology, Biology Centre CAS, Czech Republic):Progress in understanding the role of sex chromosomes in sex determination of moths and butterflies
11:30-11:50: Sander Visser (Institute of Entomology, Biology Centre CAS, Czech Republic): Sex determination in Ephestia kuehniella – variations on a common theme
11:50-12:10: Liuqi (Aloy) GU (University of Kansas, USA): Patterns and mechanism of sex chromosome dosage compensation in the Lepidoptera
12:10-12:30: Keiro UCHINO (National Institute of Agrobiological Sciences, Japan): Cryopreservation banking system of the transgenic silkworms, Bombyx mori

12:30-12:45: Poster introductions II

 Ryota Kasahara: Identification of DMRT genes and their possible roles for doublesex-independent sexual differentiation in the silkworm, Bombyx mori
Tasuku Kitamura: doublesex controls multiple characteristics of pale yellow spots in female-limited Batesian mimic butterfly, Papilio polytes
Junshan Gao: Knock down of BmSPR increases BmDHFR in a tetrahydrobioptein synthesis related silkworm mutant i-lem
Shuyi Tang: Humoral factors involved in cascade reactions inducing nodule formation in Bombyx mori larvae
Jiaping XU: Isolation of ferritin and its interaction with BmNPV in the silkworm, Bombyx mori

13:00 Lunch

14:30-15:30 Poster viewing II

15:30-17:00: Afternoon special
Afternoon special: Basic and applied research on genetically modified Lepidoptera (Bombyx mori and other species) (coordinated by Toru Shimada, Hideki Sezutsu, Jeffrey Marcus)
To be organized and announced on site by coordinators

17:00-17:30: Coffee break

17:30-20:30: Evening Session Development and Differentiation II: Cell differentiation; wing and larval patterning; molecular mimicry and adaptation; receptors and ligands; signal transduction (Session coordinators: Richard ffrench-Constant, Jeffrey Marcus, Toru Shimada, Hideki Sezutsu)

17:30 -18:00 Introductory lecture
– Featured Speaker Jeffrey Marcus (University of Manitoba, Canada): Compartment boundaries and morphogens pattern the A-P axis of Lepidoptera wings

18:00-19:20: Oral presentations from submissions

18:00-18:20: Hongyuan JIN (University of Tokyo, Japan): RNA-seq reveals molecular mechanism of larval color pattern switch in swallowtail butterfly, Papilio xuthus
18:40-19:00: Takashi KIUCHI (University of Tokyo, Japan): CRISPR/Cas9-mediated mutagenesis in the Masculinizer gene of the silkworm, Bombyx mori
19:00-19:20: Masataka SUZUKI (University of Tokyo, Japan):Transgenic expression of the piRNA-resistant Masculinizer gene induces female-specific lethality and partial female-to-male sex reversal in the silkworm, Bombyx mori

19:20-19:30: Break

19:30-20:30: Oral presentations from submissions

19:30-19:50: Toru SHIMADA (University of Tokyo, Japan): Bombyx mori embryonic lethal mutant “kidney” is caused by a defect in prostaglandin synthesis
19:50-20:10: Piotr BEBAS (University of Warsaw, Poland):Cross-talk between circadian oscillators in the nervous system and gut of caterpillars
20:10-20:30: Guoxing QUAN (Great Lakes Forestry Centre, Natural Resources Canada): Expression of small heat shock protein genes during diapause and under thermal stress in the spruce budworm, Choristoneura fumiferana

20:45  Dinner

Wednesday, August 22, 2018

07:00-08:15  Breakfast

08:30-10:15: Morning Session: Physiology and Behaviour I: Immunity; parasite and microbiotic control of insect physiology
(Session coordinators: Astrid Groot, Paul Shirk, Michel Cusson)

08:30-09:00: Introductory lecture
– Featured Speaker Mike Kanost (Kansas State University, USA): Blue Blood Proteomics: Relative and accurate measurement of hemolymph protein abundance in Manduca sexta immune response using in vivo ¹⁵N metabolic labelling and mass spectrometry

09:00-10:15: Oral presentations from submissions

 09:00-09:20: Astrid GROOT (University of Amsterdam, The Netherlands): (How) do infections contribute to the evolution of sexual attraction in moths?
09:20-09:40: Zhengyao Zhang (Dalian University of Technology, PR China): Cloning and expression analysis of genes involved in the TLL2 signaling pathway of Antheraea pernyi
09:40-10:00: Richard ffrench-Constant (Centre for Ecology and Conservation, University of Exeter, UK): A male-killing endosymbiont and a neo-W supergene enslave the African Queen
10:00-10:15: Shuyi Tang (Tokyo University of Agriculture and Technology, Japan): Humoral factors involved in cascade reactions inducing nodule formation in Bombyx mori larvae (15 min Invited talk from poster session)

10:30-11:00: Coffee break and Group Picture 

12:00 EXCURSION (location TBA; dinner at location to be announced)

21:00-22:00: Return to the Academy

Thursday, August 23, 2018

07:00-08:15  Breakfast

08:30-12:45: Morning Session: Physiology and Behaviour II: Neurobiology, hormones, neuropeptides and receptors; chemical ecology, chemosensation and behaviour
(Session coordinators: Emmanuelle Jacquin-Joly, Jürgen Krieger)

08:30-09:00: Introductory lecture
– Featured Speaker Kirk Hillier (Acadia University, Canada): Evolution of moth pheromone diversity

09:00-10:20: Oral presentations from submissions

09:00-09:20: Emmanuelle Jacquin-Joly (INRA, Institute of Ecology & Environmental Sciences of Paris, France): Molecular basis of Lepidoptera chemical communication: genomic identification and functional characterization of the Spodoptera littoralis odorant receptor repertoire
09:20-09:40: Alessandro GRAPPUTO (University of Padova, Italy): Tortricid olfaction – insight from transcriptomic comparative analysis
09:40-10:00: Chen-Zhu WANG (Institute of Zoology, Chinese AS, PR China): Expression and function of pheromone receptors in two closely related species, Helicoverpa armigera and H. assulta
10:00-10:20: Jürgen KRIEGER (Martin Luther University Halle-Wittenberg, Germany): Targeting the molecular basis of pheromone detection in Heliothis virescens

10:20-10:50: Coffee break  

10:50-12:30: Oral presentations from submissions

10:50-11:10: Kana TSUNETO (Tokyo University of Agriculture and Technology, Japan): Ultrasensitive chemosensory neurons in silkworm identify its host plant without biting
11:10-11:30: Haruka Endo (Tokyo University of Agriculture and Technology, Japan): Silkworm gustatory receptors tuned to phagostimulants
11:30-11:50: Pauline SELL (Max Planck Institute for Chemical Ecology, Germany): Effects of the main secondary metabolites of Physalis plants on a specialist and a generalist species of Lepidoptera
11:50-12:10: Takayuki YAMAGISHI (Tokyo University of Agriculture and Technology, Japan): A plant secondary metabolite induces secretion of a feeding regulatory hormone, tachykinin from endocrine cells of the silkworm midgut
12:10-12:30: Ladislav ROLLER (Institute of Zoology, Slovak AS, Slovakia): BomBase: web atlas of the neuroendocrine system in the silkworm Bombyx mori

12:30-12:45: Poster introductions III 

Piotr Bebas: Peripheral oscillators in caterpillars and insecticides metabolism
Zuzana Galikova: Expression analysis of ITP and ITPL receptors and identification of the promoter regulatory region for the ITP in the silkworm Bombyx mori
Shogo Uno: Novel hormone-producing cells in the fat body of Bombyx mori larvae
Marta Polanska: Developmental analysis of A-type allatostatin and serotonin distribution in the central nervous system of the Egyptian cotton leafworm, Spodoptera littoralis
Guozheng Zhang: Indentification and Functional Characterization of the Bombyx Neuropeptide receptor GPCR A9 for Sulfakinin from Silkworm, Bombyx mori
David Wildridge: Possible ETH role in regulation of juvenile hormone production in Bombyx mori
Mayu Kasubuchi: Molecular characterization of Bombyx mori gustatory receptor
Fumika Shii: Gustatory receptors responding to the feeding repellents of Bombyx mori larvae

13:00  Lunch

14:30-16:30: Poster viewing III

17:00-17:30: Coffee break

17:30-20:30: Evening Session: Functional Genomics and Post-genomic Tools and Applications I: Tissue and cell-specific transcriptomics and proteomics; basic regulatory mechanisms; RNA-mediated control of gene expression; RNA delivery tools; recombinant protein expression
(Session coordinators: Simon Baxter, Anjiang Tan)

17:30-18:00: Introductory lecture
– Featured Speaker Anjiang Tan (SIPPE, Shanghai, PR China): Genetic engineering of the silkworm for a better crop

18:00-19:20: Oral presentations from submissions

18:00-18:20 James WALTERS (University of Kansas, USA): Proteomic and population genomic analysis of dimorphic sperm reveals contrasting tempo and mode in the evolution of proteome composition versus molecular adaptation
18:20-18:40: Xiangfeng JING (Northwest A&F University, PR China): Phylogeny and evolution of the cholesterol transporter NPC1 in insects
18:40-19:00: Kevin DUDLEY (Queensland University of Technology, Australia): Impact of intrinsic and environmental factors on DNA methylation dynamics in Helicoverpa armigera

19:00-19:10: Break

19:10-20:10: Oral presentations from submissions

19:10-19:30: Juil KIM (National Institute of Crop Science, South Korea): Genome wide discovery and characterization of lncRNAs involved in insecticide resistance in Helicoverpa armigera
19:30-19:50: Zarel MARTINEZ (Ghent University, Belgium): Increased delivery of dsRNA by guanidine polymer for toxicity in Lepidoptera (Spodoptera exigua)
19:50-20:10: Zhi Xian LIM (The University of Queensland, Australia): Nanoparticle-mediated delivery of RNAi for management of the cotton bollworm (Helicoverpa armigera)
20:10-20:30: Gwylim BLACKBURN (Canadian Forest Service and Laval University): Genetics of flight in female gypsy moths (Lymantria spp.)

20:45  Dinner

Friday, August 24, 2018

07:00-08:15  Breakfast

08:30-12:45: Morning Session: Functional Genomics and Post-genomic Tools and Applications II: Transgenesis, paratransgenesis and genetic manipulations; genome editing (TALEN, CRISPR, others) and somatic mutagenesis, gene drive for pest control
(Session coordinators:  Tom Walsh, Hideki Sezutsu, Toru Shimada, Emmanuelle Jacquin-Joly)

08:30-09:00: Introductory lecture
– Featured Speaker Hideki Sezutsu (NARO, Tsukuba, Japan): Genetically modified silkworms for industrial applications

09:00-10:40: Oral presentations from submissions

09:00-09:40: Paul SHIRK (University of Florida, Gainesville, USA): The ABC transporter/White Gene Locus in the Indian Meal Moth, Plodia interpunctella, and Mutagenesis with CRISPR/Cas9 Gene Editing
09:40-10:00: Jung LEE (Agricultural and Environmental Biology, University of Tokyo, Japan): Forward and reverse genetics of Saturniid silkmoths
10:00-10:20: Carolina CONCHA (Smithsonian Tropical Research Institute, Panama): Comparative knock-out of WntA across 14 mimetic and divergent Heliconius butterflies
10:20-10:40: Sabine Hänniger (Max Planck Institute for Chemical Ecology, Germany): Chelation for survival –  Deciphering an insect-microbe-interaction using CRISPR/Cas9

10:40-11:00: Coffee break

11:00-12:30: Oral presentations

11:00-11:20: Muwang LI (Jiangsu University of Science and Technology, PR China): BmAbl gene plays an important role in cocoon production
11:20-11:40: Natuo KÔMOTO (National Agriculture and Food Research Organization, Japan): Comparison of the wild mulberry silkmoth, Bombyx mandarina, and the domesticated silkmoth, B. mori: a model system to study genetical basis of behavior
11:40-12:00: Mizuki OHNO (Iwate University, Japan): RNA-seq analysis facilitates BAC-FISH mapping
12:00-12:15: (15 min Invited talk from poster session)
12:15-12:30: Poster Introductions IV

Sylvie Gimenez: Characterization and expression profiling of microRNAs associated to host-plant adaptation in Lepidopteran pests of corn
Muwang Li: Analysis of microRNA expression profile in different kinds of naked pupa in silkworm
Isabelle Darboux: Identification of differentially expressed long non-coding RNAs (lncRNAs) in response to viral infection in S. frugiperda hemocytes
James Pearce: Early development and genetic engineering of Galleria mellonella
Pratanporn Banyong: Study grassery transmission under aseptic conditions
Franck Dorkeld: Exploration of viral communities associated with lepidoptera
Juil Kim: Plasticity of Diadegma fenestrale Ichnovirus (DfIV) gene expressions in hymenopteran host, D. fenestrale and lepidopteran host, Plutella xylostella
Michael Sparks: Molecular-level responses of Lymantria dispar dispar to Chromobacterium spp. infections

13:00  Lunch

14:30-15:30: Poster viewing IV

15:30-17:00: Afternoon special
Afternoon special: Genetic manipulation tools for plant eaters: fundamental technical issues and environmental perspectives (coordinated by Tom Walsh, Hideki Sezutsu, Toru Shimada)
To be organized and announced on site by coordinators

17:00-17:30: Coffee break

17:30-19:00 Evening Session: Pathology and Pest control I: Viruses, parasites, other pathogens and pest control
(Session coordinators: Paul Shirk, Michel Cusson)

17:30 -18:00: Introductory lecture
– Featured Speaker Jean-Michel Drezen (University of Tours, France): Impact of parasitic wasps and their symbiotic viruses on lepidopteran genomes

18:00-18:55: Oral presentations from submissions

18:00-18:20: Mario SOBERÓN (The National Autonomous University of Mexico, Mexico): Mechanism of action of Cry toxins produced by Bacillus thuringiensis and understanding the evolution of insect resistance to these toxins
18:20-18:40: Kangayam Muthusamy PONNUVEL (Seribiotech Research Laboratory, Bangalore, India): Molecular characterization of a novel member of iflavirus infecting Antheraea mylitta and A. proylei, the wild silkworms of India
18:40-18:55: (invited talk from poster session)

20:30  Dinner and Cretan night

Saturday , August 25, 2018

07:30-08:45  Breakfast

09:00-10:10: Morning Session: Pathology and Pest Control II: Viruses, parasites, other pathogens and pest control
(Session coordinators: Marian Goldsmith, Kostas Iatrou)

09:00-09:30: Introductory lecture
– Featured Speaker Dawn Gundersen-Rindal (USDA Beltsville, MD, USA): Viral, bacterial, and microsporidial pathogens of the lepidopteran forest pest, Lymantria dispar (gypsy moth): Comparative global gene expression and the search for optimal target genes

09:30-10:10: Oral presentations from submissions

09:30-09:50: Olle TERENIUS (Swedish University of Agricultural Sciences and Uppsala University, Sweden): Virus infections in the Autumnal Moth Epirrita autumnata
09:50-10:10: Tania GUPTA (Seribiotech Research Laboratory, Bangalore, India): Characterization and genome comparison of an Indian isolate of bidensovirus infecting the silkworm Bombyx mori

10:15-10:45: The 2021 Workshop (to include completion of a questionnaire about the 2018 meeting)

10:45: End of 2018 Workshop

12:00  Light lunch and departures