Pathogenesis and Vaccines
Microbial pathogens (viral, bacterial, fungal, etc.) infect and cause disease in all organisms, affecting both our health and economic well-being. Understanding pathogenesis involves the study of the molecular and cellular events in both the host and the pathogen that occur during the development of disease. This knowledge is critical to understanding how to treat and prevent disease. Perhaps the best way to prevent disease is the development of vaccines. In cases where protection from disease by vaccines may not be possible because the organism to be protected lacks an adaptive immune response, alternative protection strategies involving probiotics or antibiotics may be developed. As with vaccines, the key to developing these strategies requires understanding both the pathogen and the host. Faculty members associated with this CMB research focus area have internationally recognized research programs investigating microbial pathogenesis, probiotics, and vaccines for humans and animals of agricultural and aquacultural importance.